Pathogenicity and virulence of Rhodococcus equi in foals following intratracheal challenge

Veterinary Microbiology

Volumn 56, Issue 3-4, 1997, Pages 301-312

  Wada, Ryuichi ^a   Kamada, Masanobu ^a   Anzai, Toni ^a   Nakanishi, Akiko ^a   Kanemaru, Takumi ^a   Takai, Shinji ^b   Tsubaki, Shiro ^b  

^a EQUINE RESEARCH INSTITUTE   (Japan)

^b KITASATO UNIVERSITY   (Japan)

Author keywords

Pathogenesis; Rhodococcus equi; Virulence plasmid

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL PNEUMONIA; BACTERIAL VIRULENCE; CONTROLLED STUDY; HISTOPATHOLOGY; HORSE DISEASE; NONHUMAN; RHODOCOCCUS EQUI; STRAIN DIFFERENCE;

ACTINOMYCETALES INFECTIONS; ANIMALS; BODY TEMPERATURE; GRANULOMA; HORSE DISEASES; HORSES; LUNG; LUNG DISEASES; MACROPHAGES; PNEUMONIA, BACTERIAL; RHODOCOCCUS EQUI; SPECIES SPECIFICITY; TIME FACTORS; TRACHEA; VIRULENCE;

ANIMALIA; BACTERIA (MICROORGANISMS); CORYNEBACTERIUM; EQUUS CABALLUS; RHODOCOCCUS EQUI;

EID: 0030816810     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1135(97)00098-9     Document Type: Article

References (28)

1. Barton, M.D. and Embury, D.H., 1987. Studies of the pathogenesis of Rhodococcus equi infection in foals. Aust. Vet. J., 64: 332-339.
2. Barton, M.D. and Hughes, K.L., 1980. Corynebacterium equi: A review. Vet. Bull., 50: 65-80.
3. Chirino-Trejo, J.M., Prescott, J.F. and Yager, J.A., 1987. Protection of foals against experimental Rhodococcus equi pneumonia by oral immunization. Can. J. Vet. Res., 51: 444-447.
4. Johnson, J.A., Prescott, J.F. and Markham, R.J.F., 1983a. The pathology of experimental Corynebacterium equi infection in foals following intrabronchial challenge. Vet. Pathol., 20: 440-449.
5. Johnson, J.A., Prescott, J.F. and Markham, R.J.F., 1983b. The pathology of experimental Corynebacterium equi infection in foals following intragastric challenge. Vet. Pathol., 20: 450-459.
6. Konno, T., Asawa, T., Ito, H., Takai, S., Tsubaki, S. and Sekizaki, T., 1993. Restriction map of a virulent-associated plasmid of Rhodococcus equi. Plasmid, 30: 309-311.
7. Magnusson, H., 1923. Spezifische infektiose Pneumonie beim Fohlen. Ein neuer Eiterreger beim Pferd. Arch. Wiss. Prakt. Tierhelkd., 50: 22-38.
8. Martens, R.J., Fiske, R.A. and Renshaw, H.W., 1982. Experimental subacute foal pneumonia induced by aerosol administration of Corynebacterium equi. Equine Vet. J., 14: 111-116.
9. Martens, J.G., Martens, R.J., Fiske, R.A. and Hietala, S.K., 1989. Rhodococcus equi foal pneumonia: protective effects of immune plasma in experimentally infected foals. Equine Vet. J., 21: 249-255.
10. Mutimer, M.D. and Woolcock, J.B., 1982. Experimental Corynebacterium equi infection in mice. J. Reprod. Fertil. Suppl., 32: 469-476.
11. Prescott, J.F., Johnson, J.A. and Markham, R.J.F., 1980. Experimental studies on the pathogenesis of Corynebacterium equi infection in foals. Can. J. Comp. Med., 44: 280-288.
12. Prescott, J.F., 1991. Rhodococcus equi: an animal and human pathogen. Clin. Microbiol. Rev., 4: 20-34.
13. Sekizaki, T., Takai, S., Egawa, Y., Ikeda, T., Ito, H. and Tsubaki, S. 1995. Sequence of Rhodococcus equi gene coding the virulence-associated 15 to 17 kDa antigens. Gene, 155: 135-136.
14. Songer, J.G. and Prescott, J.F., 1993. Corynebacterium. In: ed. C.L. Gyles and C.O. Thoen, Pathogenesis of Bacterial Infections in Animals, 2nd Ed. Iowa State University Press, Ames, pp. 57-69.
15. Takai, S., Kawazu, S. and Tsubaki, S., 1985. Enzyme-linked immunosorbent assay for diagnosis of Corynebacterium (Rhodococcus) equi in foals. Am. J. Vet. Res., 46: 2166-2170.
16. Takai, S., Ohbushi, S., Koike, K., Tsubaki, S., Oishi, H. and Kamada, M., 1991a. Prevalence of virulent Rhodococcus equi in isolates from soil and feces of horses from horse-Breeding breeding farms with and without endemic infections. J. Clin. Microbiol., 29: 2887-2889.
17. Takai, S., Koike, K., Ohbushi, S., Izumi, C. and Tsubaki S., 1991b. Identification of 15 to 17 kilodalton antigens associated with virulent Rhodococcus equi. J. Clin. Microbiol., 29: 439-443.
18. Takai, S., Sekizaki, T., Ozawa, T., Sugawara, T., Watanabe, Y. and Tsubaki, S., 1991c. Association between a large plasmid and 15 to 17 kilodalton antigens in virulent Rhodococcus equi. Infect. Immun., 59: 4056-4060.
19. Takai, S., Anzai, T., Sasaki, Y., Tsubaki, S. and Kamada, M., 1993a. Virulence of Rhodococcus equi isolated from lesions of infected foals. Bull. Equine Res. Inst., 30: 9-14.
20. Takai, S., Watanabe, Y., Ikeda, T., Tsubaki, S., Ozawa, T., Matsukura, S., Tamada, Y. and Sekizaki, T., 1993b. Virulence-associated plasmids in Rhodococcus equi. J. Clin. Microbiol., 31: 1726-1729.
21. Takai, S. Iie, M., Kobayashi, C., Morishita, T., Nishio, Y., Ishida, T., Fujimura, T., Sasaki, Y. and Tsubaki, S., 1993c. Monoclonal antibody specific to virulence-associated 15 to 17 kilodalton antigens of Rhodococcus equi. J. Clin. Microbiol., 31: 2780-2782.
22. Takai, S., Kitajima, H., Tamada, Y., Matsukura, S., Ohwa, Y., Inui, T., Kato, M., Seno, N., Anzai, T., Kanemaru, T. and Kamada, M., 1994a. Humoral antibody response to the antigens of virulent Rhodococcus equi in foals. J. Equine Sci., 5: 121-126.
23. Takai, S., Takahagi, J., Sato, Y., Yamaguchi, K., Kakizaki, S., Takehara, S., Matsukura, S., Tamada, Y., Tani, A., Sasaki, Y., Tsubaki, S. and Kamada, M., 1994b. Molecular epidemiology of virulent Rhodococcus equi in horses and their environments. In: ed. H. Nakajima and P.D. Rossdale, Equine Infectious Diseases VII. R&W Publications (Newmarket) Ltd., pp. 183-187.
24. Takai, S., Madarame, H., Matsumoto, C., Inoue, M., Sasaki, Y., Hasegawa, Y., Tsubaki, S. and Nakane, A., 1995. Pathogenesis of Rhodococcus equi infection in mice: Roles of virulence plasmids and granuolmagenic activity of bacteria. FEMS Immunol. Med. Microbiol., 11: 181-190.
25. Tan, C., Prescott, J.F., Patterson, M.C. and Nicholson, V.M., 1995. Molecular characterization of a lipid-modified virulence-associated protein of Rhodococcus equi and its potential in protective immunity. Can. J. Vet. Res., 59: 51-59.
26. Wilks, C.R., Barton, M.D. and Allison, J.F., 1982. Immunity to and immunotherapy of Rhodococcus equi. J. Reprod. Fertil., Suppl., 32: 497-505.
27. Yager, J.A., 1987. The pathogenesis of Rhodococcus equi pneumonia in foals. Vet. Microbiol., 14: 225-232.
28. Zink, M.C. and Yager, J.A., 1987. Experimental infection of piglets by aerosols of Rhodococcus equi. Can. J. Vet. Res., 51: 290-296.