T-cell, antibody, and cytokine responses to homologs of the 60- kilodalton heat shock protein in helicobacter pylori infection

Clinical and Diagnostic Laboratory Immunology

Volumn 4, Issue 4, 1997, Pages 440-446

  Sharma, Smita A ^a,c   Miller, Geraldine G ^a   Peek Jr , Richard A ^a,b   Pérez Pérez, Guillermo I ^a   Blaser, Martin J ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Lando and Anastasi LLP   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEAT SHOCK PROTEIN;

ADULT; ANTIBODY RESPONSE; ARTICLE; CLINICAL ARTICLE; CROSS REACTION; HELICOBACTER PYLORI; HUMAN; IMMUNE RESPONSE; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0030816361     PISSN: 1071412X     EISSN: None     Source Type: Journal    
DOI: 10.1128/cdli.4.4.440-446.1997     Document Type: Article

References (48)

1. Barrios, C., C. Tougne, B. S. Polla, P. H. Lambert, and G. Del Giudice. 1994. Specificity of antibodies induced after immunization of mice with the mycobacterial heat shock protein of 65kD. Clin. Exp. Immunol. 98:224-228.
2. Blander, S. J., and M. A. Horowitz. 1993. Major cytoplasmic membrane of Legionella pneumophila, a genus common antigen and member of the hsp60 family of heat shock proteins, induces protective immunity in a guinea pig model of Legionnaires' disease. J. Clin. Invest. 91:717-723.
3. Blaser, M. J. 1990. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J. Infect. Dis. 161:626-633.
4. Blaser, M. J. 1992. Hypotheses on the pathogenesis and natural history of Helicobacler pylori-induced inflammation. Gastroenterology 102:720-727.
5. Blaser, M. J., and J. Parsonnet. 1994. Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J. Clin. Invest. 94:4-8.
6. Crabtree, J. E., T. M. Shallcross, R. V. Heatley, and J. I. Wyatt. 1991. Mucosal tumor necrosis factor alpha and interleukin-6 in patients with Helicobacter pylori associated gastritis. Gut 32:1473-1477.
7. Del Giudice, G., A. Gerraix, P. Costantino, C. A. Wyler, C. Tougne, E. R. de Graeff-Meeder, J. van Embden, R. V. der Zee, L. Nencioni, R. Rappuoli, S. Sutcr, and P. H. Lambert. 1993. Priming to heat shock proteins in infants vaccinated against pertussis. J. Immunol. 150:2025-2032.
8. + T-cell clones from peripheral blood and gastric biopsies. Infect. Immun. 63:1102-1106.
9. Dooley, C. P., H. Cohen, P. L. Fitzgibbons, M. Bauer, M. D. Appleman, G. I. Pérez-Pérez, and M. J. Blaser. 1989. Prevalence of Helicobacter pylon infection and histologic gastritis in asymptomatic persons. N. Engl. J. Med. 321: 1562-1566.
10. Drumm, B., G. I. Pérez-Pérez, M. J. Blaser, and P. M. Sherman. 1990. Intrafamilial clustering of Helicobacter pylori infection. N. Engl. J. Med. 322:359-363.
11. Dunn, B. E., R. M. Roop II, C.-C. Sung, S. A. Sharma, G. I. Perez-Perez, and M. J. Blaser. 1992. Identification and purification of a cpn60 heat shock protein homolog from Helicobacter pylori. Infect. Immun. 60:1946-1951.
12. Elson, C. J., and S. J. Thompson. 1994. Immunity, autoimmunity and immunotherapy: new frontiers in heat shock protein research. Clin. Exp. Immunol. 98:175-177.
13. Engstrand, L., A. Scheynius, and C. Pahlson. 1991. An increased number of gamma/delta T-cells and gastric epithelial cell expression of the GroEL stress-protein homologue in Helicobacter pylori-associated chronic gastritis of the antrum. Am. J. Gastroenterol. 86:976-980.
14. Fan, X. J., A. Chua, M. A. O'Connell, D. Kelleher, and P. W. N. Keeling. 1992. Interferon-gamma and tumor necrosis factor production in patients with Helicobacter pylori infection. Ir. J. Med. Sci. 162:408-411.
15. Ferrero, R. L., J. M. Thiberge, I. Kansau, N. Wuscher, M. Huerre, and A. Labigne. 1995. The GroES homolog of Helicobacter pylori confers protective immunity against mucosal infection in mice. Proc. Natl. Acad. Sci. USA 92:6499-6503.
16. Forman, D., D. G. Newell, F. Fullerton, J. W. Yarnell, A. R. Stacey, N. Wald, and F. Sitas. 1991. Association between infection with Helicobacter pylori and risk of gastric cancer: evidence from a prospective investigation. Br. Med. J. 302:1302-1305.
17. Gionchetti, P., D. Vaira, M. Campieri, J. Holton, M. Menegatti, A. Belluzzi, E. Bertinelli, M. Ferretti, C. Brignola, M. Miglioli, and L. Barbara. 1994. Enhanced mucosal interlcukin-6 and -8 in Helicobacter pylori positive dyspeptic patients. Am. J. Gastroenterol. 89:883.
18. Ilangumaran, S., N. P. Shanker Narayan, G. Ramu, and V. Muthukkaruppan. 1994. Cellular and humoral immune responses to recombinant 65-kD antigen of Mycobacterium leprae in leprosy patients and healthy controls. Clin. Exp. Immunol. 96:79-85.
19. Kansau, I., J. M. Thiberge, R. L. Ferrero, S. Suerbaum, and A. Labigne. 1994. Immunological and functional properties of the HspA and HspB heat-shock proteins of Helicobacter pylori. Am. J. Gastroenterol. 89:1326.
20. Kartunnen, R. 1991. Blood lymphocyte proliferation, cytokine secretion and appearance of T cells with activation surface markers in cultures with Helicobacter pylori. Comparison of the responses of subjects with and without antibodies to H. pylori. Clin. Exp. Immunol. 83:396-400.
21. Kelso, A. 1995. Th1 and Th2 subsets: paradigms lost? Immunol. Today 16:374-379.
22. Kiessling, R., A. Gronberg, J. Ivanyi, K. Soderstrom, M. Ferm, S. Kleinau, E. Nilsson, and L. Klareskog. 1991. Role of hsp60 during autoimmune and bacterial inflammation. Immunol. Rev. 121:91-111.
23. Kuhn, R., J. Lohler, D. Rennick, K. Rajewsky, and W. Muller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:263-274.
24. Lee, A., J. Fox, and S. Hazell. 1993. Pathogenicity of Helicobacter pylori: a perspective. Infect. Immun. 61:1601-1610.
25. Lucey, D. R., M. Clerici, and G. M. Shearer. 1996. Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases. Clin. Microbiol. Rev. 9:532-562.
26. Macchia, G., A. Massone, D. Burroni, A. Covacci, S. Censini, and R. Rappuoli. 1993. The hsp60 protein of Helicobacter pylori: structure and immune response in patients with gastrointestinal diseases. Mol. Microbiol. 9:645-652.
27. Moore, K. W., A. O'Garra, R. de Waal Malefyt, P. Vieira, and T. R. Mossmann. 1993. Interleukin 10. Annu. Rev. Immunol. 11:165-185.
28. Mossmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of Iymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145-173.
29. Negrini, R., L. Lisato, I. Zanella, L. Cavazzini, S. Gullini, V. Villanacci, C. Poiesim, A. Albertini, and S. Cielmi. 1991. Helicobacter pylori infection induces antibodies cross-reacting with human gastric mucosa. Gastroenterology 101:437-445.
30. Negrini, R., C. Poiesi, A. Savio, A. Paterlini, F. Buffoli, P. Cesari, and S. Ghielmi. 1994. Molecular mimicry of gastric antigens by Helicobacter pylori: a role in the pathogenesis of atrophic gastritis? Am. J. Gastroenterol. 89: 1329.
31. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. 1994. NIH consensus conference. Helicobacter pylori in peptic ulcer disease. JAMA 272:65-69.
32. Noach, L. A., N. B. Bosnia, J. Jansen, F. J. Hoek, S. J. H. van Deventer, and G. N. J. Tytgat. 1994. Mucosal tumor necrosis factor-α, interleukin-1β, and interleukin-8 production in patients with Helicobacter pylori infection. Scand. J. Gastroenterol. 29:425-429.
33. Nomura, A., G. N. Stemmermann, P. H. Chyou, I. Kato, G. I. Pérez-Pérez, and M. J. Blaser. 1991. Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N. Engl. J. Med. 325:1132-1136.
34. Perez-Perez, G. I., and M. J. Blaser. 1987. Conservation and diversity of Campylobacter pyloridis major antigens. Infect. Immun. 55:1256-1263.
35. Pérez-Pérez, G. I., B. M. Dworkin, J. E. Chodos, and M. J. Blaser. 1988. Campylobacter pylori antibodies in humans. Ann. Intern. Med. 109:11-17.
36. Pérez-Pérez, G. I., W. R. Brown, T. L. Cover, B. E. Dunn, P. Cao, and M. J. Blaser. 1994. Correlation between serological and mucosal inflammatory responses to Helicobacter pylori. Clin. Diagn. Lab. Immunol. 1:325-329.
37. Peterson, W. L. 1991. Helicobacter pylori and peptic ulcer disease. N. Engl. J. Med. 324:1043-1048.
38. Roche, P. W., W. J. Theuvenet, and W. J. Britton. 1992. Cellular immune responses to mycobacterial heat shock proteins in Nepali leprosy patients and controls. Int. J. Lepr. 60:36-39.
39. Sharma, S. A., G. G. Miller, G. I. Pérez-Pérez, R. S. Gupta, and M. J. Blaser. 1994. Humoral and cellular immune recognition of Helicobacler pylori proteins are not concordant. Clin. Exp. Immunol. 97:126-132.
40. Singh, B., and R. S. Gupta. 1992. Expression of human 60-kD heat shock protein (HSP60 or P1) in Escherichia coli and the development and characterization of corresponding monoclonal antibodies. DNA Cell Biol. 11: 489-496.
41. Strauss, R. M., T. C. Wang, P. B. Kelsey, C. C. Compton, M. J. Ferraro, G. Pérez-Pérez, J. Parsonnet, and M. J. Blaser. 1990. Association of Helicobacter pylori infection with dyspeptic symptoms in patients undergoing gastroduodenoscopy. Am. J. Med. 89:464-469.
42. Tarkkanen, J., T. U. Kosunen, and E. Saksela. 1993. Contact of lymphocytes with Helicobacter pylori augments natural killer cell activity and induces production of gamma interferon. Infect. Immun. 61:3012-3016.
43. Trejdosiewicz, L. K., A. Calabrese, C. J. Smart, D. J. Oakes, P. D. Howdle, J. E. Crabtree, M. S. Losowsky, F. Lancaster, and A. W. Boylston. 1991. γσ T cell receptor-positive cells of the human gastrointestinal mucosa: occurrence and V region expression to Helicobacter pylori-associated gastritis, coeliac disease and inflammatory bowel disease. Clin. Exp. Immunol. 84: 440-444.
44. Wanidworanum, C., and W. Strober. 1993. Predominant role of tumor necrosis factor-α in human monocyte IL-10 synthesis. J. Immunol. 151:6853-6861.
45. Yamamura, M., K. Uyemura, R. J. Dans, K. Weinberg, T. H. Rea, B. R. Bloom, and R. L. Modlin. 1991. Defining protective responses to pathogens: cytokine profiles in leprosy skin lesions. Science 254:277-279.
46. Yi, Y., G. Zhong, and R. C. Brunham. 1993. Continuous B-cell epitopes in Chlamydia trachomatis heat shock protein 60. Infect. Immun. 61:1117-1120.
47. Yoshida, N., D. N. Granger, D. J. Evans, D. G. Evans, D. Y. Graham, D. C. Anderson, R. E. Wolf, and P. R. Kvietys. 1993. Mechanisms involved in Helicobacter pylori-induced inflammation. Gastroenterology 105:1431-1440.
48. Young, D. B., A. Mehlert, and D. F. Smith. 1990. Stress proteins and infectious diseases, p. 131-165. In R. J. Morimoto et al., Stress proteins in biology and medicine. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.