Synthesis of certain 2-substituted-4-substitutedmethyl thiazole derivatives as potential antitumor agents

Scientia Pharmaceutica

Volumn 65, Issue 3, 1997, Pages 99-108

  Abdelal, Ali M M ^a   Kheira, Samy M M ^a   Badria, Farid A ^a  

^a MANSOURA UNIVERSITY   (Egypt)

Author keywords

1,2,4 triazole; 4 substitutedmethyl thiazole; Antibacterial screening; Antitumour activity; Synthesis

Indexed keywords

ANTINEOPLASTIC AGENT; CIPROFLOXACIN; FLUOROURACIL; THIAZOLE DERIVATIVE;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

EID: 0030815677     PISSN: 00368709     EISSN: 22180532     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Silverman R.B. "The organic Chemistry of drug design and drug action", Academic press; London (1992), pp 263.
2. SchnurR., Gallaschun R.J., Singleton D.H., Grissom M., Sloan D., Goodwin P., McNiff. P.A., Fliri A.F., Mangano F.A., Olson T.H., Pollack V.A. (1991), J Med. Chem., 34: 1975.
3. Grawande N.G. , Shingare N.S (1987), Indian J. Chem. 26B :387
4. Bhamaria R., Bellare R. Deliwala C. (1968), Indian J. Exp. Biol.. 6: 62.
5. El-Subbagh, H.I. , El-Nagar, W.A., Badria, F.A. (1994), Med. Chem. Res. 3 : 503 and references cited there.
6. Toan L.Q., Tefac D. (1962), Farmacia. 10:9 ; Chem. Abstract (1963), 58: 3408g
7. Toan L.Q., Tefac D. (1962), Farmacia. 10:9 ; Chem. Abstract (1963), 58: 3408g
8. Abdelal A.M., Massoud M.A., El-Kerdawy M.M., Broom A.D. (1992), Chin. Pharm. J.. 44(2) :103
9. Sawhney S.N., Arora S.K., Singh S.P. (1978), Indian J. Chem. 523 :168.
10. Jain S.R., Kar A. (1971), Planta Med. 20:118.
11. Abdelal, A.M., Moustafa, M.A., Shehata , I.A., El-Emam A.A. (1991), Sci. Pharm. 59: 265.
12. Wise R., Andrews T.M., Edward L. (1983), Antimicrob. Ag. Chemother. 23, 559.
13. Badria F.A., Shier W. T. (1994), Sci. Pharm., 62: 347.
14. Dushinsky F., Pleven E. (1957), J. Am. Chem. Soc., 79, 4559.