Extraction of artemisinin and artemisinic acid from Artemisia annua L. using supercritical carbon dioxide

Journal of Chromatography A

Volumn 785, Issue 1-2, 1997, Pages 353-360

  Kohler, Marcel ^a   Haerdi, Werner ^a   Christen, Philippe ^a   Veuthey, Jean Luc ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Artemisinic acid; Artemisinin

Indexed keywords

ARTEMISIA ANNUA EXTRACT; ARTEMISIN; ARTEMISINIC ACID; CARBON DIOXIDE; METHANOL; SOLVENT;

ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG STRUCTURE; GAS CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; SUPERCRITICAL FLUID CHROMATOGRAPHY; SUPERCRITICAL FLUID EXTRACTION; ULTRASOUND;

ANTIMALARIALS; ARTEMISIA; ARTEMISININS; CARBON DIOXIDE; CHROMATOGRAPHY, GAS; DRUGS, CHINESE HERBAL; FLAME IONIZATION; KINETICS; PLANTS, MEDICINAL; SESQUITERPENES;

ARTEMISIA ANNUA;

EID: 0030815350     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(97)00403-2     Document Type: Article

References (30)

1. World Malaria Situation in 1993, WHO, Geneva, 1996.
2. L.H. Miller, Science 257 (1992) 36-38.
3. D.L. Klayman, Science 228 (1985) 1049-1055.
4. H.J. Woerdenbag, C.B. Lugt, N. Pras, Pharm. Weekbl. Sci. Ed. 12 (1990) 169-181.
5. T.T. Hien, N.J. White, Lancet 341 (1993) 603-608.
6. G. Schmid, J. Am. Chem. Soc. 105 (1983) 624-625.
7. H.J. Woerdenbag, N. Pras, N.G. Chan, B.T. Bang, R. Bos, W. Van Uden, P. Van Y, N.V. Boi, S. Batterman, C.B. Lugt, Planta Med. 60 (1994) 272-275.
8. N. Debrunner, V. Dvorak, P. Magalhaes, N. Delabays, Proceedings of the International symposium on Breeding Research on Medicinal and Aromatic Plants, Quedlinburg, Germany, July 1996, 222-225.
9. Z. Shisan, Z. Mei-Yi, Anal. Chem. 58 (1986) 289-292.
10. N. Acton, D.L. Klayman, I.J. Rollman, Planta Med. 51 (1985) 445-446.
11. N. Pras, J.F. Visser, S. Batterman, H.J. Woerdenbag, T.M. Malingré, C.B. Lugt, Phytochem. Anal. 2 (1991) 215-219.
12. A.T. Sipahimalani, D. Fulzelle, M.R. Heble, J. Chromatogr. 538 (1991) 452-455.
13. H.J. Woerdenbag, N. Pras, R. Bos, J.F. Visser, H. Hendriks, T.M Malingré, Phytochem. Anal. 2 (1991) 215-219.
14. M. Jaziri, B. Diallo, M. Vanhaelen, J. Homès, K. Yoshimatsu, K. Shimomura, Phytochemistry 33 (1993) 821-826.
15. M. Kohler, W. Haerdi, P. Christen, J.-L. Veuthey, J. High Resol. Chromatogr. 20 (1997) 62-66.
16. D.L. Klayman, A.J. Lin, N. Acton, J. Nat. Prod. 47 (1984) 715-717.
17. M.B. King, T.R. Bott, Extraction of Natural Products using Near-critical Solvents, Blackie Academic and Professional, Glasgow, 1995.
18. J. King, in: B. Wenclawiak (Ed.), Analysis with Supercritical Fluids: Extraction and Chromatography, Springer-Verlag, Berlin, 1992, pp. 32-60.
19. S. Hawthorne, in: Supercritical Fluid Extraction and Its Use in Chromatographic Sample Preparation, Blackie Academic and Professional, Glasgow, 1993, pp. 39-64.
20. P. Castioni, P. Christen, J.-L. Veuthey, Analusis 23 (1995) 95-106.
21. C.D. Bevan, P.S. Marshall, Nat. Prod. Rep. 11 (1994) 451-466.
22. W.K. Modey, D.A. Mulholland, M.W. Raynor, Phytochem. Anal. 7 (1996) 1-15.
23. R.M. Smith, R.D. Burford, J. Chromatogr. 600 (1992) 175-181.
24. R.M. Smith, R.D. Burford, J. Chromatogr. 627 (1992) 255-261.
25. J. Castañeda-Acosta, A.W. Cain, N.H. Fisher, F.C. Knopf, J. Agric. Food 43 (1995) 63-68.
26. M.M. Paris-Paslawska, Artémisinine et dérivés, nouveaux médicaments anti-paludiques, Thesis No. 2575, University of Geneva, 1993, pp. 36-39, pp. 74-78.
27. M. Kohler, personal communication.
28. J. Goupy, La Méthode des Plans d'Expériences, Dunod, Paris, 1988.
29. J.F. Ferreira, J. Janick, Int. J. Plant Sci. 156 (1995) 807-815.
30. M.V. Duke, R.N. Paul, H.N. Elsohly, G. Sturtz, S.O. Duke, Int. J. Plant Sci. 155 (1994) 365-372.