Suppression of infectious virus spread and corneal opacification by the combined use of recombinant interferon beta and interleukin-10 following corneal infection with herpes simplex virus-1 in mice

Antiviral Research

Volumn 36, Issue 2, 1997, Pages 99-105

  Minagawa, Hiroko ^a   Sakai, Yuichiro ^a   Li, Yu yu ^a   Ishibashi, Tatsuro ^a   Inomata, Hajime ^a   Mori, Ryoichi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Herpes simplex virus; Herpetic stromal keratitis; Immunopathology; Interferon; Interleukin 10

Indexed keywords

BETA INTERFERON; INTERLEUKIN 10;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA; HERPES; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; IMMUNOPATHOLOGY; IN VITRO STUDY; KERATITIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; UNIVERSITY; VIROGENESIS;

ANIMALS; CORNEAL OPACITY; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; HERPESVIRUS 1, HUMAN; HUMANS; INTERFERON-BETA; INTERLEUKIN-10; KERATITIS, HERPETIC; MICE; MICE, INBRED BALB C; PLAQUE ASSAY; RECOMBINANT PROTEINS;

ANIMALIA; HERPES; HUMAN HERPESVIRUS 1; MURINAE;

EID: 0030815315     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(97)00044-2     Document Type: Article

References (22)

1. Avery A.C., Zhao Z.-S., Rodriguez A., Bikoff E.K., Soheilian M., Foster C.S., Cantor H. Resistance to herpes stromal keratitis conferred by an IgG2a-derived peptide. Nature. 376:1995;431-434.
2. Babu J.S., Thomas J., Kanangat S., Morrison L.A., Knipe D.M., Rouse B.T. Viral replication is required for induction of ocular immunopathology by herpes simplex virus. J. Virol. 70:1996;101-107.
3. Balish M.J., Abrams M.E., Pumfery A.M., Brandt C.R. Enhanced inhibition of herpes simplex virus type 1 growth in human corneal fibroblasts by combinations of interferon-α and -γ J. Infect. Dis. 166:1992;1401-1403.
4. Chen S.-H., Oakes J.E., Lausch R.N. Synergistic anti-herpes effect of TNF-α and IFN-γ in human corneal epithelial cells compared with that in corneal fibroblasts. Antiviral Res. 25:1994;201-213.
5. Doymaz, M.Z., Rouse, B.T., 1992. Immunopathology of herpes simplex virus infections. In: Rouse, B.T. (Ed.), Herpes Simplex Virus. Pathogenesis, Immunobiology and Control. Springer, Berlin, pp. 121-136.
6. Fraser-Smith E.B., Epstein D.A., Marsh Y.V., Matthews T.R. Enhanced efficacy of the acyclic nucleoside 9-(1,3-dehydroxy-2-propoxymethyl) guanine in combination with beta-interferon against herpes simplex virus type 2 in mice. Antimicrob. Agents Chemother. 25:1984;563-565.
7. Hendricks R.L., Tumpey T.M., Finnegan A. IFN-γ and IL-2 are protective in the skin but pathologic in the corneas of HSV-1-infected mice. J. Immunol. 149:1992;3023-3028.
8. Hendricks R.L., Weber P.C., Taylor J.L., Koumbis A., Tumpey T.M., Glorioso J.C. Endogeneously produced interferon α protects mice from herpes simplex virus type 1 corneal disease. J. Gen. Virol. 72:1991;1601-1610.
9. Ikemoto K., Pollard R.B., Fukumoto T., Morimatsu M., Suzuki F. Small amounts of exogenous IL-4 increase the severity of encephalitis induced in mice by the intranasal infection of herpes simplex virus type 1. J. Immunol. 155:1995;1326-1333.
10. Kumano Y., Yamamoto M., Mori R. Protection against herpes simplex virus infection in mice by recombinant murine interferon-β in combination with antibody. Antiviral Res. 7:1987;289-301.
11. Li Y.-y., Minagawa H., Tanaka S., Mori R. Suppression of infectious virus spread to the liver by foscarnet following lethal infection of acyclovir-resistant herpes simplex virus type 2 in mice. Antiviral Res. 27:1995;111-121.
12. Mestan J., Brockhaus M., Kirchner H., Jacobsen H. Antiviral activity of tumour necrosis factor. Synergism with interferons and induction of oligo-2′, 5′-adenylate synthetase. J. Gen. Virol. 69:1988;3113-3120.
13. Minagawa H., Takenaka A., Mohri S., Mori R. Protective effect of recombinant murine interferon beta against mouse hepatitis virus infection. Antiviral Res. 8:1987;85-95.
14. Minkovits J., Pepose J. Topical interferon α-2a treatment of herpes simplex keratitis resistant to multiple antiviral medications in an immunosuppressed patient. Cornea. 14:1995;326-330.
15. Naito T., Nitta K., Kinouchi Y., Shiota H., Mimura Y. Effects of 9-(1,3-dihydroxy-2-proxymethyl) guanine (DHPG) eye drops and cyclosporine eye drops in the treatment of herpetic stromal keratitis in rabbits. Curr. Eye Res. 10:1991;s201-s203.
16. Ophir J., Brenner S., Bali R., Kriss-Leventon S., Smetana Z., Revel M. Effect of topical interferon-beta on recurrence rates in genital herpes: a double-blind, placebo-controlled, randomized study. J. Interferon Cytokine Res. 15:1995;625-631.
17. Sakai Y., Minagawa H., Ishibashi T., Inomata H., Mori R. Stromal keratitis induced by a unique clinical isolate of herpes simplex virus type 1. Ophthalmologica. 208:1994;157-160.
18. Schmitt D.A., Sasaki H., Pollard R.B., Suzuki F. Antiviral effects of recombinant human tumor necrosis factor-alpha in combination with natural interferon-beta in mice infected with herpes simplex virus type 1. Antiviral Res. 19:1992;347-352.
19. Smith P.M., Wolcott R.M., Chervenak R., Jennings S.R. Control of acute cutaneous herpes simplex virus infection: T cell-mediated viral clearance is dependent upon interferon-γ (IFN-γ). Virology. 202:1994;76-88.
20. Tang Q., Hendricks R.L. Interferon γ regulates platelet endothelial cell adhesion molecule 1 expression and neutrophil infiltration into herpes simplex virus-infected mouse corneas. J. Exp. Med. 184:1996;1435-1447.
21. Tumpey T.M., Elner V.M., Chen S.-H., Oakes J.E., Lausch R.N. Interleukin-10 treatment can suppress stromal keratitis induced by herpes simplex virus type 1. J. Immunol. 153:1994;2258-2265.
22. Whitley, R.J., 1996. Herpes simplex viruses. In: Fields, B.N., Knipe, D.M., Howley, P.M. et al. (Eds.), Fields Virology, 3rd edition. Lippincott-Raven, Philadelphia, PA, pp. 2297-2342.