Mechanism of concordant corneal xenograft rejection in mice: Synergistic effects of anti-leukocyte function-associated antigen-1 monoclonal antibody and FK506

Transplantation

Volumn 64, Issue 1, 1997, Pages 42-48

  Yamagami, Satoru ^a,b   Isobe, Mitsuaki ^c   Yamagami, Hiroko ^d   Hori, Junko ^b   Tsuru, Tadahiko ^b  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXYSPERGUALIN; CD4 ANTIGEN; CLASSICAL COMPLEMENT PATHWAY C3 C5 CONVERTASE; CYCLOPHOSPHAMIDE; CYCLOSPORIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M; IMMUNOGLOBULIN M ANTIBODY; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; METHOTREXATE; MONOCLONAL ANTIBODY; TACROLIMUS;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA TRANSPLANTATION; DRUG MECHANISM; GRAFT REJECTION; GRAFT SURVIVAL; HISTOPATHOLOGY; IMMUNOMODULATION; IMMUNOSUPPRESSIVE TREATMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; SURVIVAL TIME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY FORMATION; ANTIBODY SPECIFICITY; CORNEAL TRANSPLANTATION; DRUG SYNERGISM; GRAFT REJECTION; GRAFT SURVIVAL; HYPERSENSITIVITY, DELAYED; IMMUNITY, CELLULAR; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MALE; MICE; MICE, INBRED BALB C; RATS; RATS, INBRED LEW; SPLEEN; TACROLIMUS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0030814698     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199707150-00009     Document Type: Article

References (35)

1. Streilein JW, Bradley D, Sano Y, Sonoda Y. Immunosuppressive properties of tissue obtained from eyes with experimentally manipulated corneas. Invest Ophthalmol Vis Sci 1996; 37: 413.
2. Niederkorn JY. Immune privilege and immune regulation in the eye. Adv Immunol 1990; 48: 191.
3. Platt JL, Vercellotti GM, Dalmasso AP, et al. Transplantation of discordant xenografts: a review of progress. Immunol Today. 1990; 11: 450.
4. Bach P. Discordant xenografting: a summary and look to the future. Transplant Proc 1992; 24: 739.
5. Ross JR, Howell DN, Sanfilippo FP. Characteristics of corneal xenograft rejection in a discordant species combination. Invest Ophthalmol Vis Sci 1993; 34: 2469.
6. Larkin DFP, Takano T, Standfield SD, Williams KA. Experimental orthotopic corneal xenotransplantation in the rat. Transplantation 1995; 60: 491.
7. Bogaerde JVD, Aspinall R, Wang MW, et al. Induction of long-term survival of hamster heart xenografts in rats. Transplantation 1991; 52: 15.
8. Cramer DV, Chapman FA, Jaffee BD, et al. The prolongation of concordant hamster-to-rat cardiac xenografts by brequinar sodium. Transplantation 1992; 54: 403.
9. Hansen R, Bogaerde JVD, Wallwork J, White DJG. Evidence that long-term survival of concordant xenografts is achieved by inhibition of antispecies antibody production. Transplantation 1992; 54: 408.
10. Murase N, Starzl TE, Demetris AJ, et al. Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs. Transplantation 1993; 55: 701.
11. Matsumiya G, Shirakura R, Miyagawa S, et al. Analysis of rejection mechanism in the rat to mouse cardiac xenotransplan-tation. Transplantation 1994; 57: 1653.
12. Miwa S, Kawasaki S, Makuuchi M, et al. Role of ICAM-1and LFA-1 n a cardiac xenograft rejection model. Transplant Proc 1995; 27: 111.
13. Corry RJ, Cutkomp J, Oberholser JH, Kapelanski DP, Wakely E. Prolongation of allograft and xenograft survival with 15-deoxyspergualin. Transplant Proc 1989; 257(21): 530.
14. Gorczynski RM, Fu X-M, Chung S, Sullivan B, Chen Z. Manipulation of xenogeneic skin and/or renal graft survival in the rat-mouse concordant combination by portal vein pretransplant transfusion. Transplant Immunol 1995; 3: 321.
15. Umesue M, Mayumi H, Nishimura Y, et al. Xenogeneic (rat to mouse) skin tolerance induced by monoclonal antibodies, xenogeneic cells, and cyclophosphamide. Transplant Proc 1995; 27: 315.
16. Nishi M, Herbort CP, Matsubara M, et al. Effects of the immunosuppressant FK506 on a penetrating keratoplasty rejection model in the rat. Invest Ophthalmol Vis Sci 1993; 34: 2477.
17. He Y, Ross J, Niederkorn JY. Promotion of murine orthotopic corneal allograft survival by systemic administration of anti-CD4 monoclonal antibody. Invest Ophthalmol Vis Sci 1994; 35: 3218.
18. He YG, Mellon J, Apte B, Niederkorn JY. Effect of LFA-1and ICAM-1antibody treatment on murine corneal allograft survival. Invest Ophthalmol Vis Sci 1994; 35: 3218.
19. Yamagami S, Obata H, Tsuru T, Isobe M. Suppression of corneal allograft rejection after penetrating keratoplasty by antibodies to ICAM-1and LFA-1 in mice. Transplant Proc 1995; 27: 1899.
20. Yamagami S, Tsuru T, Isobe M, Obata H, Suzuki J. The role of cell adhesion molecules in allograft rejection after penetrating keratoplasty in mice: clinical and immunohistochemical study. Graefes Arch Clin Exp Ophthalmol 1996; 234: 382.
21. Minamoto A, Sakata H, Okada K, Fujihara M. Suppression of corneal graft rejection by subconjunctival injection of FK-506 in a rat model of penetrating keratoplasty. Jpn J Ophthalmol 1995; 39: 12.
22. Pleyer U, Milani JK, Dukes A, et al. Effect of topically applied anti-CD4 monoclonal antibodies on orthotopic corneal allografts in a rat model. Invest Ophthalmol Vis Sci 1995; 35: 52.
23. Nishimura T, Yagi H, Sato N, Ohta S, Hashimoto Y. The role of lymphokine-activated cell-associated antigen: inhibition of T-cell activation by monoclonal killer-blocking antibody. Cell Immunol 1987; 107: 32.
24. Coffman RL, Weissman IL. B220: a B cell-specific member of the T200 glycoprotein family. Nature 1981; 289: 681.
25. Spielgelberg HL. Biological activities of immunoglobulins of different classes and subclasses. Adv Immunol 1974; 19: 259.
26. Tanaka H, Kuroda A, Marusawa H, et al. Physicochemical properties of FK-506, a novel immunosuppressant isolated from Streptomyces tsukubaensis. Transplant Proc 1987; 19 (suppl): 11.
27. Kino T, Hatanaka H, Hashimoto M, et al. FK-506, a novel immunosuppressant isolated from a Streptomyces: 1. Fermentation, isolation, and physicochemical and biological characteris-tics. J Antibiot (Tokyo) 1987; 40: 1249.
28. Springer TA. Adhesion receptors of the immune system. Nature 1990; 346: 425.
29. Isobe M, Yagita H, Okumura K, Ihara A. Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1. Science 1992; 255: 1125.
30. Talento A, Nguyen M, Blake T, et al. A single administration of LFA-1 antibody confers prolonged allograft survival. Transplantation 1993; 55: 418.
31. Thomson AW, Proppar DJ, Woo J, Whiting PH, Milton JI, Ma-cleod AM. Comparative effects of rapamycin, FK506 and cyclosporine on antibody production, lymphocyte populations and immunoglobulin isotype switching in the rat. Immunopharmacol Immunotoxicol 1993; 15: 355.
32. Schwartz RH. A cell culture model for T lymphocyte clonal anergy. Science 1990; 248: 1349.
33. Tocci MJ, Matkovich DA, Collier KA, et al. The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes. J Immunol 1989; 143: 718.
34. Bashuda H, Takazawa K, Tamatani T, Miyasaka M, Yagita H, Okumura K. Induction of persistent allograft tolerance in the rat by combined treatment with anti-leukocyte function-associated antigen-1 and anti-intercellular adhesion molecule-1 monoclonal antibodies, donor-specific transfusion, and FK506. Transplantation 1996; 62: 117.
35. Larsen CP, Elwood ET, Alexander DZ, et al. Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathways. Nature 1996; 381: 434.