Cholecystokinin receptors do not mediate the behavioral effects of lipopolysaccharide in mice

Physiology and Behavior

Volumn 62, Issue 2, 1997, Pages 385-389

  Bluthé, Rose Marie ^a   Michaud, Bruno ^a   Kelley, Keith W ^b   Dantzer, Robert ^a  

^a CEMAGREF   (France)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Behavior; CCK A receptors; CCK B receptors; Cholecystokinin (CCK); Lipopolysaccharide; Mice; Sickness; Social exploration

Indexed keywords

1 (2,3 DIHYDRO 1 METHYL 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL) 3 (3 METHYLPHENYL)UREA; CHOLECYSTOKININ; CHOLECYSTOKININ A RECEPTOR; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ RECEPTOR; CHOLECYSTOKININ RECEPTOR BLOCKING AGENT; DEVAZEPIDE; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; ILLNESS BEHAVIOR; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOCIAL BEHAVIOR;

EID: 0030814633     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-9384(97)00035-8     Document Type: Article

References (51)

1. Bluthé R. M., Parnet P., Dantzer R., Kelley K. W. Interleukin-1 receptor antagonist blocks effects of IL- 1α and IL- 1β on social behaviour and body weight in mice. Neurosci. Res. Comm. 9:1991;151-158.
2. Bluthé R. M., Walter V., Parnet P., Layé S., Lestage J., Verrier D., Poole S., Stenning B. E., Kelley K. W., Dantzer R. Lipopolysaccharide induces sickness behavior in rats by a vagal mediated mechanisms. C. R. Acad. Sci. (Série III) Paris. 317:1994;499-503.
3. Bluthé R. M., Michaud B., Kelley K. W., Dantzer R. Vagotomy attenuates behavioral effects of interleukin-1 injected peripherally but not centrally. NeuroReport. 7:1996;1485-1488.
4. Bluthé R. M., Michaud B., Kelley K. W., Dantzer R. Vagotomy blocks behavioural effects of interleukin-1 injected via the intraperitoneal route but not via other systemic routes. NeuroReport. 7:1996;2823-2827.
5. Bonnafous C. Troubles moteurs digestifs associés aux benzodiazépines et à leur sevrage chez le rat: rôle de la cholécystokinine et de la sérotonine. 1995;Thèse de diplôme de Doctorat.
6. Branchereau P., Böhme G. A., Champagnat J., Morin-Surun M-P., Durieux C., Blanchard J. C., Roques B. P., Denavit-Saubié M. Cholecystokinin A and cholecystokinin B receptors in neurons of the brainstem solitary complex of the rat: pharmacological identification. J. Pharmacol. Exp. Ther. 260:1992;1433-1440.
7. Bret-Dibat J. L., Bluthé R. M., Kent S., Kelley K. W., Dantzer R. Lipopolysaccharide and interleukin-1 depress food-motivated behavior in mice by a vagal-mediated mechanism. Brain Behav. Immun. 9:1995;242-246.
8. Chang R. S. L., Lotti V. J. Biochemical and pharmacological characterization of an extremely potent and selective nonpeptide cholecystokinin antagonist. Proc. Nat. Acad. Sci. USA. 83:1986;4923-4926.
9. 3H]-(±)-L-364,718: a new potent, nonpeptide cholecystokinin antagonist radioligand selective for peripheral receptors. Mol. Pharmacol. 30:1986;212-217.
10. 3H]-L-365,260: a new potent and selective brain cholecystokinin (CCK-B) and gastrin receptor antagonist radioligand. Mol. Pharmacol. 35:1989;803-808.
11. Corp E. S., McQuade J., Moran T. H., Smith G. P. Characterization of type A and type B CCK receptor binding sites in rat vagus nerve. Brain Res. 623:1993;161-166.
12. Crawley J. N. Clarification of the behavioral functions of peripheral and central cholecystokinin: two separate peptide pools. Peptides. 6:1985;129-136.
13. Crawley J. N., Kiss J. Z., Mezey E. Bilateral midbrain transection block the behavioral effects of cholecystokinin on feeding and exploration in rats. Brain Res. 322:1984;316-321.
14. Dantzer R. How do cytokines say hello to the brain? Neural versus humoral mediation. Eur. Cytokine Netw. 5:1994;271-273.
15. Dantzer R., Bluthé R. M., Kent S., Goodall G. Behavioral effects of cytokines: an insight into mechanisms of sickness behavior. De Souza E. Neurobiology of cytokines. 1993;130-150 Academic Press, Orlando, FL.
16. Daun J. M., McCarthy D. O. The role of cholecystokinin in interleukin-1-induced anorexia. Physiol. Behav. 54:1993;237-241.
17. Dockray G. J. Immunochemical evidence of cholecystokinin-like peptides in brain. Nature (London). 264:1976;568-570.
18. Dourish C. T., Hill D. R. Classification and function of CCK receptors. Trends Pharmacol. Sci. 8:1987;207-208.
19. Fleshner M., Goehler L. E., Hermann J., Relton J. K., Maier S. F., Watkins L. R. Interleukin- 1β -induced corticosterone elevation and hypothalamic NE depletion is vagally mediated. Brain Res. Bull. 37:1995;605-610.
20. Flood J. F., Smith G. E., Morley J. E. Modulation of memory processing by cholecystokinin: dependence on the vagus nerve. Science. 236:1987;832-834.
21. Gaykema R. P. A., Dijkstra I., Tilders F. J. H. Subdiaphragmatic vagotomy suppresses endotoxin-induced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion. Endocrinology. 136:1995;4717-4720.
22. Goldbach, J. M.; Roth, J.; Zeisberger, E. Fever suppression by subdiaphragmatic vagotomy in guinea pigs depends on the route of pyrogen administration. Am. J. Physiol. (in press).
23. Henderson B., Poole S., Wilson M. Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. Microbiol. Rev. 60:1996;316-341.
24. Hill D. R., Campell N. J., Shaw T. M., Soodruff G. N. Autoradiographic localization and biochemical characterization of peripheral type CCK receptors in rat CNS using highly selective nonpeptide CCK antagonists. J. Neurosci. 7:1987;2967-2977.
25. 3H-MK329. J. Neurosci. 10:1990;1070-1081.
26. Layé S., Bluthé R-M., Kent S., Combe C., Medina C., Parnet P., Kelley K. W., Dantzer R. Subdiaphragmatic vagotomy blocks the induction of interleukin- 1β mRNA in the brain of mice in response to peripherally administered lipopolysaccharide. Am. J. Physiol. Regul. Integ. Comp. Physiol. 268:1995;R1327-R1331.
27. Lehmann A. Atlas stéréotaxique du cerveau de la souris. 1974;Editions du Centre National de la Recherche Scientifique, Paris.
28. Lemaire M., Barnéoud P., Böhme G. A., Piot O., Haun F., Roques B. P., Blanchard J. C. CCK-A and CCK-B receptors enhance olfactory recognition via distinct neuronal pathways. Learning Memory. 1:1994;153-164.
29. Lemaire M., Piot O., Roques B. P., Böhme G. A., Blanchard J. C. Evidence for an endogenous cholecystokininergic balance in social memory. NeuroReport. 3:1992;929-932.
30. Li B-H., Rowland N. E. Effects of vagotomy on cholecystokinin- and dexfenfluramine-induced Fos-like immunoreactivity in the rat brain. Brain Res. Bull. 37:1995;589-593.
31. Lin T. H., Lin J. H. Effects of protein binding and experimental disease states on brain uptake of benzodiazepines in rats. J. Pharmacol. Exp. Ther. 253:1990;45-50.
32. Lotti V. J., Chang R. S. L. A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260. Eur. J. Pharmacol. 162:1989;273-280.
33. Lotti V. J., Pendleton R. G., Gould R. J., Hanson H. M., Chang R. S. L., Clineschmidt B. V. In vivo pharmacology of L-364,718, a new potent nonpeptide peripheral cholecystokinin antagonist. J. Pharmacol. Exp. Ther. 241:1987;103-109.
34. Mercer J. G., Lawrence C. B. Selectivity of cholecystokinin (CCK) receptor antagonists, MK-329 and L-365,260, for axonally-transported CCK binding sites on the rat vagus nerve. Neurosci. Lett. 137:1992;229-231.
35. Moran T. H., McHugh P. R. Cholecystokinin suppresses food intake by inhibiting gastric emptying. Am. J. Physiol. Regul. Integ. Comp. Physiol. 242:1982;R491-R497.
36. Moran T. H., Smith G. P., Hostetler A. M., McHugh P. R. Transport of cholecystokinin (CCK) binding sites in subdiaphragmatic vagal branches. Brain Res. 415:1987;149-152.
37. Niijima A. The afferent discharges from sensors for interleukin- 1β in the hepato-portal system in the anesthetized rat. J. Physiol. 446:1992;236P.
38. Ohgo S., Nakatsuru K., Ishikawa E., Matsukura S. Stimulation of cholecystokinin (CCK) release from superfused rat hypothalamo-neuro-hypophyseal complexes by interleukin-1 (IL-1). Brain Res. 593:1992;25-31.
39. Pullen R. G. L., Hodgson O. J. Penetration of diazepam and the non-peptide CCK antagonist, L-364,718 into rat brain. J. Pharm. Pharmacol. 39:1987;863-864.
40. Sacerdote P., Ruff M. R., Pert C. B. Cholecystokinin and the immune system: receptor-mediated chemotaxis of human and rat monocytes. Peptides. 9:((Suppl. 1)):1988;29-34.
41. Silver A. J., Flood J. F., Song A. M., Morley J. E. Evidence for a physiological role for CCK in the regulation of food intake in mice. Am. J. Physiol. Regul. Integ. Comp. Physiol. 256:1989;R646-R652.
42. Smith G. P., Jerome C., Cushin B. J., Eterno R., Simansky K. J. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science. 213:1981;1036-1037.
43. Székely M., Szelényi Z., Balasko M. Cholecystokinin participates in the mediation of fever. Pflügers Arch. 428:1994;671-673.
44. Szelényi Z., Bartho L., Székely M., Romanovsky A. A. Cholecystokinin octapeptide (CCK-8) injected into a cerebral ventricle induced a fever-like thermoregulatory response mediated by type B CCK-receptors in the rat. Brain Res. 638:1994;69-77.
45. Wan W., Wetmore L., Sorensen C. M., Greenberg A. H., Nance D. M. Neural and biochemical mediators of endotoxin and stress-induced c-fos expression in the rat brain. Brain Res. Bull. 34:1994;7-14.
46. Watanobe H., Sasaki S., Takebe K. Involvement of oxytocin and cholecystokinin-8 in interleukin- 1β -induced adrenocorticotropin secretion in the rat. Neuroimmunomodulation. 2:1995;88-91.
47. Watkins L. R., Goehler L. E., Relton J. K., Tartaglia N., Silbert L., Martin D., Maier S. F. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neurosci. Lett. 183:1995;27-31.
48. Watkins L. R., Wiertelak E. P., Furness L. E., Maier S. F. Illness-induced hyperalgesia is mediated by spinal neuropeptides and excitatory amino acids. Brain Res. 664:1994;17-24.
49. Weatherford S. C., Chiruzzo F. Y., Laughton W. B. Satiety induced by endogenous and exogenous cholecystokinin is mediated by CCK-A receptors in mice. Am. J. Physiol. Regul. Integ. Comp. Physiol. 262:1992;R574-R578.
50. Wettstein J. G., Buéno L., Junien J. L. CCK antagonists: pharmacology and therapeutic interest. Pharmac. Ther. 62:1994;267-282.
51. Zarbin M. A., Wamsley J. K., Innis R. B., Kuhar M. J. Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve. Life Sci. 29:1981;697-705.