The effects of anesthesia on the biodistribution of drugs in rats: A carboplatin study

Cancer Chemotherapy and Pharmacology

Volumn 40, Issue 6, 1997, Pages 521-525

  Sancho, Alfredo R ^a,b   Dowell, James A ^a   Wolf, Walter ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Radiopharmacy Program   (United States)

Author keywords

195mPt; Anesthetics; Carboplatin; Drug biodistribution; Pharmacokinetics; PK imaging

Indexed keywords

ANESTHETIC AGENT; CARBOPLATIN; KETAMINE; PENTOBARBITAL; THIOPENTAL; XYLAZINE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; BRAIN; CEREBELLUM; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG URINE LEVEL; ERYTHROCYTE; FEMALE; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; ISOTOPE LABELING; KIDNEY; PRIORITY JOURNAL; RAT;

ANESTHETICS; ANIMALS; ANTINEOPLASTIC AGENTS; CARBOPLATIN; CEREBELLUM; DRUG INTERACTIONS; FEMALE; KIDNEY; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 0030814477     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002800050696     Document Type: Article

References (20)

1. Bacha DM, Caparros-Sison B, Allen JA, Walker R, Tan CTC (1986) Phase I study of carboplatin (CBDCA) in children with cancer. Cancer Treat Rev 70: 865
2. Brammer A, West CD, Allen SL (1993) A comparison of propofol with other injectable anesthetics in a rat model for measuring cardiovascular parameters. Lab Anim 27: 250
3. Canetta R, Rozencweig M, Carter SK (1985) Carboplatin: the clinical spectrum to date. Cancer Treat Rev 12(A):125
4. Cleare MJ (1974) Transition metal complexes in cancer chemotherapy. Coordination Chem Rev 12: 349
5. Foster BJ, Clagett-Carr K, Leyland-Jones B, Hoth D (1985) Results of NCI-sponsored phase 1 trials with carboplatin. Cancer Treat Rev 12(A):43
6. Harrap KR, Jones M, Wilkinson CR, Clink HM, Sparrow S, Mitchley BCV, Clarke S, Veasey A (1988) Antitumor, toxic and biochemical properties of cisplatin and eight other platinum complexes. In: Prestayko AW, Crooke ST, Carter SK (eds) Cisplatin: current status and new developments. Academic Press, New York, p 193
7. Jain RK (1994) Barriers to drug delivery in solid tumors. Sci Am 44: 58
8. Knight TF, Sansom S, Hawk L, Frankfurt SJ, Weinman EJ (1978) The effects of anesthesia on the excretion of an isotonic saline load in the rat. Pflugers Arch 373: 139
9. Newell DR, Siddik ZH, Gumbrell LA, Boxall FE, Gore ME, Smith IE, Calvert AH (1987) Plasma free platinum pharmacokinetics in patients treated with high dose carboplatin. Eur J Cancer Clin Oncol 23(9): 1399
10. 19SmPt-carboplatin. Pharm Res 11, S-34
11. Peckham M, Horwich A, Brada M, Drury A, Hendry WF (1985) Cis-diammine-1,1-cyclobutane dicarboxylate platinum II (carboplatin) in the treatment of testicular germ cell tumours: a preliminary report. Cancer Treat Rev 12(A):101
12. Siddik ZH, Jones M, Boxall FE, Harrap KR (1988) Comparative distribution and excretion of carboplatin and cisplatin in mice. Cancer Chemother Pharmacol 21: 19
13. Smit EF, Willemse PHB, Sleijfer Dth, Uges DRA, Postmus PE, Meijer S, Terheggen PMAB, Mulder NH, de Vries EGE (1991) Continuous infusion carboplatin on a 21-day schedule: A phase I and pharmacokinetic study. J Clin Oncol 9(1): 100
14. Smith IE, Evans BD (1985) Carboplatin (JM8) as a single agent and in combination in the treatment of small cell lung cancer. Cancer Treat Rev 12(A):73
15. Sternberg C, Kelsen D, Dukeman M, Leichman L, Heelan R (1985) Carboplatin: a new platinum analog in the treatment of epidermoid carcinoma of the esophagus. Cancer Treat Rev 69: 1305
16. Thomsen K, Olesen OV (1981) Effect of anesthesia and surgery on urine flow and electrolyte excretion in different rat strains. Renal Physiol 4: 165
17. Tinker N, De Spiegeleer B, Sharma H, Jackson H, McAuliffe C, Reman J (1990) The tissue distribution in rats of [195mPt]carboplatin following intravenous, intraperitoneal and oral administration. Nucl Med Biol 17(4):427
18. Vijgh WJF van der (1991) Clinical pharmacokinetics of carboplatin. Clin Pharmacokinet 21(4):242
19. Walter SJ, Zewde T, Shirley DG (1989) The effect of anesthesia and standard clearance procedures on renal function in the rat. Q J Exp Physiol 74: 805
20. Wiltshae E (1985) Ovarian trials at the Royal Marsden Hospital. Cancer Treat Rev 12(A):67