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Chew EY, Klein ML, Ferris FI, Remaley NA, Murphy RP, Chantry K, •• Hoogwerf BJ, Miller D: Association of elevated serum lipid levels with retinal hard exudate in diabetic retinopathy: Early Treatment Diabetic Retinopathy Study (ETDRS) Report 22. Arch Ophthalmol 1996, 98:741-756. This article reports the data from a large clinical trial of patients with both type I and II diabetes. The association of retinal hard exudate with elevated serum lipid levels is demonstrated. The results of these analyses also suggest the importance of lowering elevated levels of serum lipid for maintaining good vision in persons with diabetic retinopathy.
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Gordon B, Chang S, Kavanagh M, Berrocal M, Yannuzzi L, Robertson C, • Drexler A: The effects of lipid lowering on diabetic retinopathy. Am J Ophthalmol 1991, 112:385-391. This is the most recent study of lipid lowering pharmacologically in patients with diabetic retinopathy and elevated serum lipid levels. All six patients experienced a reduction in the retinal hard exudate but only one patient had visual improvement.
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Am J Ophthalmol
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