Signal sources in bold contrast FMRI

Advances in Experimental Medicine and Biology

Volumn 413, Issue , 1997, Pages 19-25

  Turner, Robert ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BRAIN PERFUSION; CONTRAST ENHANCEMENT; HUMAN; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTICAL RESOLUTION; PRIORITY JOURNAL; SIGNAL DETECTION;

EID: 0030814139     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4899-0056-2_2     Document Type: Article

References (31)

1. Stehling M.K., Turner R., Mansfield P., 1991, Echo-planar imaging: magnetic resonance imaging in a fraction of a second. Science 254: 43-50
2. Pauling, L. and Coryell, C.D., 1936, The magnetic properties and structure of hemoglobin, oxyhemoglobin and carbonmonoxyhemoglobin. Proc Natl Acad Sci USA 22: 210-216
3. Brindle, K.M., Brown, F.F., Campbell, I.D., Grathwohl, C., Kuchel, P.W., 1979, Application of spin-echo nuclear magnetic resonance to whole-cell systems. Biochem J, 180: 37-44
4. Thulborn, K.R., Waterton, J.C., Matthews, P.M., Radda, G.K., 1982, Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim. Biophys. Acta. 714: 265-270
5. Brooks, R.A., Di Chiro, G., 1987, Magnetic resonance imaging of stationary blood: a review. Med. Phys. 14: 903-913
6. Ogawa, S., Lee, T-M., Nayak, A.S., Glynn, P., 1990, Oxygenation-sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields. Magn. Reson. Med. 14: 68-78
7. Turner, R., LeBihan, D., Moonen, C.T.W., DesPres, D. and Frank, J., 1991, Echo-planar time course MRI of cat brain oxygenation changes, Magn. Reson. Med., 22:159-166
8. Turner, R., Le Bihan, D., Maier, J., Vavrek, R., Hedges, L.K., Pekar, J., 1990, Echo-planar imaging of intravoxel incoherent motion. Radiology 177: 407-414
9. Doyle, M., Turner, R., Cawley, M., Glover, P., Morris, G.K., Chapman, B., Ordidge, R.J., Coxon, R., Coupland, R.E., Worthington, B.S., Mansfield, P., 1986, Real-time cardiac imaging of adults at video frame rates by magnetic resonance imaging. Lancet ii: 682.
10. Jezzard, P., Heineman, F., Taylor, J., Despres, D., Wen, H., Balaban, R.S. and Turner, R., 1994, Comparison of EPI gradient-echo contrast changes in cat brain caused by respiratory challenges with direct simultaneous spectrophotometric evaluation of cerebral oxygenation via a cranial window, NMR in Biomedicine, 7:35-44
11. Ogawa, S, Tank, D.W., Menon, R., Ellerman, J.M., Kim, S-G., Merkle, H. and Ugurbil, K., 1992, Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging, Proc. Natl. Acad. Sci. USA, 89:5951-5955
12. Kwong, K.K., Belliveau, J.W., Chester, D.A., Goldberg, I.E., Weisskoff, R.M., Poncelet, B.P., Kennedy, D.N., Hoppel, B.E., Cohen, M.S., Turner, R., Cheng, H-M., Brady, T.J., Rosen, B.R., 1992, Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89: 5675-5679
13. Fox, P.T. and Raichle, M.E., 1986, Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc. Natl. Acad. Sci. USA 83: 1140-4
14. Penfield, W., 1933, The evidence for a cerebral vascular mechanism in epilepsy. Ann Intern Med 7: 303-310
15. Turner, R., Jezzard, P., Wen, H., Kwong, K.K., Le Bihan, D., Zeffiro, T., Balaban, R.S., 1993, Functional mapping of the human visual cortex at 4 tesla and 1.5 tesla using deoxygenation contrast EPI. Magn. Reson. Med. 29: 277-281
16. Fisel, C.R., Ackerman, J.L., Buxton, R.B., Garrido, L., Belliveau, J.W., Rosen, B.R., Brady, T.J., 1991, MR contrast due to microscopically heterogenous magnetic susceptibility: numerical simulations and applications to cerebral physiology. Magn. Reson. Med. 17: 336-347
17. Ogawa, S., Menon, R.S., Tank, D.W., Kim, S-G., Merkle, H., Ellerman, J.M. and Ugurbil, K., 1993, Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. Biophys. J. 64: 803-812
18. Weisskoff, R.M., Zuo, C.S., Boxerman, J.L. and Rosen, B.R., 1994, Microscopic susceptibility variation and transverse relaxation: theory and experiment. Magn. Reson. Med., 31: 601-610
19. Kennan, R.P., Zhong, J. and Gore, J.C., 1994, Intravascular susceptibility contrast mechanisms in tissues. Magn. Reson. Med., 31:9-21
20. Boxerman, J.L., Weisskoff, R.M., Kwong, K.K., Davis, T.L., Rosen, B.R., 1994, The intravascular contribution to fMRI signal change: modelling and diffusion-weighted in vivo studies. Proc. Soc. Magn. Reson. (1994) 2: 619
21. Menon, R.S., Hu, X., Adriany, G., Andersen, P., Ogawa, S. and Ugurbil, K., 1994, Comparison of spinecho EPI, asymmetric spin-echo EPI and conventional EPI applied to functional neuroimaging: the effect of flow crushing gradients on the BOLD signal. Proc. Soc. Magn. Reson. (1994) 2: 622
22. Hossmann, K-A., Ueki, M., Kocher, M. and Linn, F., 1991, Multiparametric imaging of coupling between functional activity, blood flow and metabolism uder physiological and pathophysiologic conditions, in Brain Work and Mental Activation, Alfred Benzon Symposium 31, (Lassen NA, Ingvar DH, Raichle ME and Friberg L, eds) pp 158-173. Copenhagen: Munksgaard
23. Duling, B., Matsuki, T., Segal, S., Conduction in the resistance-vessel wall: contributions to vasomotor tone and vascular communication. In: Bevan, J.A. ed. The Resistance Vasculature. Totowa, NJ: Humana Press, 1991: 193-215
24. Frostig, R.D., Lieke, E.E., Ts'o, D.Y., Grinvald, A., 1990, Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in-vivo high-resolution optical imaging of intrinsic signals. Proc Natl Acad. Sci USA 87: 6082-6086
25. Turner, R. and Grinvald, A., 1994, Direct visualization of patterns of deoxygenation and reoxygenation in monkey cortical vasculature during functional brain activation. Proc. Soc. Magn. Reson. (1994) 1: 430
26. Lai, S., Hopkins. A.L., Haacke, E.M., Li, D., Wasserman, B.A., Buckley, P., Friedman, L., Meltzer, H., Hedera, P., Friedland, R., 1993, Identification of vascular structures as a major source of signal contrast in high resolution 2D and 3D functional activation imaging of the motor cortex at 1.5 T: preliminary results. Magn. Reson. Med. 30: 387-392
27. Segebarth, C., Belle, V., Delon, C., Massarelli, R., Decety, J., Le Bas, J.F., Decorps, M., Benabid, A.L., 1994, Functional MRI of the human brain. Predominance of signals from extracerebral veins. NeuroReport 5, 813-816
28. Henkelman, R.M., Neil, J.J., Xiang, Q-S., 1994, A quantitative interpretation of IVIM measurements of vascular perfusion in the rat brain. Magn. Reson. Med. 32: 464-469
29. Wiederman, M.P., 1963, Dimensions of blood vessels from distributing artery to collecting vein. Circ. Res. 12: 375
30. Frahm, J., Merboldt, K-D., Hänicke, W., Kleinschmidt, A., Boecker, H., 1994, Brain or vein - oxygenation or flow? On signal physiology in functional MRI of human brain activation. NMR in Biomedicine 7: 45-53
31. Baker, J.R., Hoppel, B.E., Stern, C.E., Kwong, K.K., Weisskoff, R.M., Rosen, B.R., 1993, Dynamic functional imaging of the complete human cortex using gradient echo and asymmetric spin-echo echo-planar magnetic resonance imaging. Proc. Soc. Magn. Reson. Med. (1993) 3: 1400