Biological activities and metabolites from Trevoa trinervis Miers

Phytotherapy Research

Volumn 11, Issue 7, 1997, Pages 504-507

  Delporte, Carla L ^a   Backhouse, C Nadine ^a   Erazo, Silvia ^a   Negrete, Rosa E ^a   Silva, Carolina ^a   Hess, Andrés ^a   Muñoz, Orlando ^a   García Grávalos, M Dolores ^b   San Feliciano, Arturo ^c  

^a UNIVERSITY OF CHILE   (Chile)

^b PHARMAMAR S A   (Spain)

^c UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Antiinflammatory; Antipyretic; Cytotoxic activities; Steroid; Trevoa trinervis; Triterpenoids

Indexed keywords

BETULIC ACID; OLEANOLIC ACID; PLANT EXTRACT; SITOSTEROL; TREVOA TRINERVIS EXTRACT; UNCLASSIFIED DRUG; URSOLIC ACID;

ANIMAL CELL; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPYRETIC ACTIVITY; ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SCREENING; FEMALE; GUINEA PIG; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA P 388; LUNG CARCINOMA; MALE; MELANOMA CELL; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PHYTOCHEMISTRY; RABBIT; TRADITIONAL MEDICINE; TUMOR CELL;

TREVOA TRINERVIS;

EID: 0030813767     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1573(199711)11:7<504::AID-PTR145>3.0.CO;2-O     Document Type: Article

References (17)

1. Backhouse, N., Delporte, C., Negrete, R, Muñoz, O., and Ruiz, R. (1994). Antiinflammatory and antipyretic activities of Maytenus boaria Mol. Int. J. Pharmacog. 32, 239-244.
2. Betancor, C., Cortés, M., Hernández, R., and Suárez, E. (1982). Trevoagenins C and D, dammarane triterpenes from Trevoa trinervis Miers. Tetrahedron Lett. 23(10), 1125-1126.
3. Betancor, C., Freire, R., Hernández, R., Suárez, E., Cortés, M., Prangué, T., and Pascard, C. (1983). Dammarane triterpenes of Trevoa trinervis: Structure and absolute stereochemistry of trevoagenins A, B and C. Chem. Soc. Perkin Trans. 1, 1119-1126.
4. Cortés, M. (1974). Sapogeninas Triterpénicas de Trevoa trinervis Miers. PhD. Thesis, University of La Laguna, Tenerife, Spain.
5. Gónzalez, A. G., Cortés, M. and Suárez, E. (1974). Stereochemistry of trevoagenin A and B and configuration at C24 of the 2OR-ocotillones. Tetrahedron Lett. 33, 2791-2792.
6. Hollander, M., Wolfe, D. (1973). Nonparametric Statistical Methods. John Wiley & Sons, New York, pp. 27-32, 62-70.
7. Kapil, A., and Sharma, S. (1994). Anti-complement activity of oleanolic acid: an inhibitor of C3-convertase of the classical complement pathway. J. Pharm. Pharmacol. 46, 922-923.
8. 13C NMR spectra of pentacylic triterpenoids. A compilation and some salient features. Phytochemistry 37, 1517-1575.
9. Muñoz, M., Barrera, M., and Meza, I. (1981). El Uso Medicinal de Plantas Nativas y Naturalizadas en Chile, p. 91. Publicación Ocasional No. 33, Museu Nacional de Historia Natural, Santiago, Chile.
10. Najid, A., Simon, A., Cook, J., Chable-Rabinovich, H., Delage, C., Chulia, A. J., and Rigaud, M. (1992). Characterisation of ursolic acid as a lipoxygenase and cyclooxygenase inhibitor using macrophages, platelets and differentiated HL60 leukaemic cells. FEBS Lett. 299, 213-217.
11. Pisha, E., Chai, H., Lee, I. S. et al. (1995). Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis. Nature Medicine 1, 1046-1051.
12. Recio, M., del C., Giner, R. M., Mañez, S., Gueho, J., Julien, H. R., Hostettmann, K., and Rios, J. L. (1995). Investigations on the steroidal antiinflammatory activity of triterpenoids from Diospyros leucomeas. Planta Med. 61, 9-12.
13. Samuelsson, B. (1987). An elucidation of the arachidonic acid cascade. Discovery of prostaglandins, thromboxane and leukotrienes, Drugs 33 (Suppl. 1), 2-9.
14. Sánchez, E., and Torres, R. (1971). Alkaloids and friedelin from several Chilean Rhamnaceae species. An. Asoc. Quim. Argent. 59, 343-346.
15. Saper, C. B., and Breder, C. D. (1994). The neurologic basis of fever. New Engl. J. Med. 330, 1880-1886.
16. Singh, G. B., Singh, S., Bani, B., Gupta, B. D., and Banerjee, S. K. (1992). Antiinflammatory activity of oleanolic acid in rats and mice. J. Pharm. Pharmacol. 44, 456-458.
17. Winter, C. A., Risley, E. A., and Nuss, G. W. (1963). Antiinflammatory and antipyretic activities of indomethacin, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-indole-3-acetic acid. J. Therap. Exp. Pharmacol. 141, 369-373.