Immunological control of murine gammaherpesvirus infection is independent of perforin

Journal of General Virology

Volumn 78, Issue 8, 1997, Pages 2025-2030

  Usherwood, Edward J ^a   Brooks, James W ^b   Sarawar, Sally R ^b   Cardin, Rhonda D ^b   Young, William D ^a   Allen, Deborah J ^a   Doherty, Peter C ^b   Nash, Anthony A ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 6; PERFORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HERPES; HERPES VIRUS; LUNG INFECTION; LUNG LAVAGE; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN; TRANSGENIC MOUSE; VIRUS INFECTION;

ANIMALIA; CHORIOMENINGITIS VIRUS; HERPES; HERPESVIRIDAE; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MURINAE; MUS MUSCULUS;

EID: 0030813507     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-78-8-2025     Document Type: Article

References (34)

1. Bender, B. S., Croghan, T., Zhang, L. & Small, P. A., Jr. (1992). Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge. Journal of Experimental Medicine 175, 1143-1145.
2. Blaskovic, D., Stancekova, M., Svobodova, J. & Mistrikova, J. (1980). Isolation of five strains of herpes viruses from two species of free living rodents. Acta Virologica 24, 468.
3. + T cells. Journal of Experimental Medicine 184, 863-871.
4. Crawford, D. H., Edwards, J. M. B., Sweny, P., Hoffbrand, A. V. & Janossy, G. (1981). Studies on long-term T-cell-mediated immunity to Epstein-Barr virus in immunosuppressed renal allograft recipients. International Journal of Cancer 28, 705-709.
5. Efstathiou, S., Ho, Y. M. & Minson, A. C. (1990a). Cloning and molecular characterization of the murine herpesvirus 68 genome. Journal of General Virology 71, 1355-1364.
6. Efstathiou, S., Ho, Y. M., Hall, S., Styles, C. J., Scott, S. D. & Gompels, U. A. (1990b). Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri. Journal of General Virology 71, 1365-1372.
7. Ehtisham, S., Sunil-Chandra, N. P. & Nash, A. A. (1993). Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells. Journal of Virology 67, 5247-5252.
8. - γδ-T cells recovered from mice with influenza pneumonia. Journal of Immunology 147, 2069-2074.
9. + T cells. Journal of Experimental Medicine 174, 875-880.
10. Franco, M. A., Tin, C., Rott, L. S., Van Cott, J. L., McGhee, J. R. & Greenberg, H. B. (1997). Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, Fas and gamma interferon. Journal of Virology 71, 479-486.
11. Guidotti, L. G., Ishikawa, T., Hobbs, M. V., Matzke B., Schreiber, R. & Chisari, F. V. (1996). Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 4, 25-36.
12. + T cells requires direct targeting to virus-infected epithelium. European Journal of Immunology 25, 111-116.
13. + T cells. Journal of Immunology 149, 1319-1325.
14. + T cell mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity. European Journal of Immunology 24, 3068-3072.
15. Kägi, S., Ledermann, B., Bürki, K., Seiler, P., Odermatt, B., Olsen, K. J., Podack, E. R., Zinkernagel, R. M. & Hengartner, H. (1994b). Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369, 31-37.
16. Kägi, D., Seiler, P., Pavlovic, J., Ledermann, B., Burki, K., Zinkernagel, R. M. & Hengartner, H. (1995). The roles of perform- and Fas-dependent cytotoxicity in protection against cytopathic and non-cytopathic viruses. European Journal of Immunology 25, 3256-3262.
17. Kast, W. M., Roux, L., Curren, J., Blom, H. J. J., Voordouw, A. C., Meloen, R. H., Kolakofsky, D. & Melief, C. J. M. (1991). Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide. Proceedings of the National Academy of Sciences, USA 88, 2283-2287.
18. Lin, M. T., Stohlman, S. A. & Hinton, D. R. (1997). Mouse hepatitis virus is cleared from the central nervous system of mice lacking perforin-mediated cytolysis. Journal of Virology 71, 383-391.
19. Lowin, B., Beermann, F., Schmidt, A. & Tschopp, J. (1994). A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity. Proceedings of the National Academy of Sciences, USA 91, 11571-11575.
20. Lukacher, A. E., Braciale, V. L. & Braciale, T. J. (1984). In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific. Journal of Experimental Medicine 160, 814-826.
21. Nash, A. A., Usherwood, E. J. & Stewart, J. P. (1996). Immunological features of murine gammaherpesvirus infection. Seminars in Virology 7, 125-130.
22. Sarawar, S. R. & Doherty, P. C. (1994). Concurrent production of interleukin-2, interleukin-10 and gamma interferon in the regional lymph nodes of mice with influenza pneumonia. Journal of Virology 68, 3112-3119.
23. Sarawar, S. R., Cardin, R. D., Brooks, J. W., Mehrpooya, M., Tripp, R. A. & Doherty, P. C. (1996). Cytokine production in the immune response to murine gammaherpesvirus-68. Journal of Virology 70, 3264-3268.
24. Sunil-Chandra, N. P., Efstathiou, S., Arno, J. & Nash, A. A. (1992a). Virological and pathological features of mice infected with murine gammaherpesvirus 68. Journal of General Virology 73, 2347-2356.
25. Sunil-Chandra, N. P., Efstathiou, S. & Nash, A. A. (1992b). Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo. Journal of General Virology 73, 3275-3279.
26. Sunil-Chandra, N. P., Efstathiou, S. & Nash, A. A. (1993). Interactions of murine gammaherpesvirus 68 with B and T cell lines. Virology 193, 825-833.
27. Sunil-Chandra, N. P., Arno, J., Fazakerley, J. & Nash, A. A. (1994). Lymphoproliferative disease in mice infected with murine gammaherpesvirus 68. American Journal of Pathology 145, 818-826.
28. Taylor, P. M. & Askonas, B. A. (1986). Influenza nucleoprotein-specific cytotoxic T cell clones are protective in vivo. Immunology 58, 417-420.
29. + T cells promote the clearance of influenza virus from major histocompatibility complex class II-/-respiratory epithelium. Journal of Virology 70, 1288-1291.
30. Usherwood, E. J., Ross, A. J., Allen, D. J. & Nash, A. A. (1996). Murine gammaherpesvirus-induced splenomegaly: a critical role for CD4 T cells. Journal of General Virology 77, 627-630.
31. Walsh, C. M., Glass, A. A., Chiu, V. & Clark, W. R. (1994a). The role of the Fas lytic pathway in a perforin-less CTL hybridoma. Journal of Immunology 153, 2506-2514.
32. Walsh, C. M., Matloubian, M., Liu, C.-C., Ueda, R., Kurahara, C. G., Christensen, J. L., Huang, M. T. F., Young, J. D.-E., Ahmed, R. & Clark, W. R. (1994b). Immune function in mice lacking the perform gene. Proceedings of the National Academy of Sciences, USA 91, 10854-10858.
33. Yang, Y., Xiang, Z., Ertl, H. C. J. & Wilson, J. M. (1995). Upregulation of class I major histocompatibility complex antigens by interferon γ is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo. Proceedings of the National Academy of Sciences, USA 92, 7257-7261.
34. Yao, Q. Y., Rickinson, A. B., Gaston, J. S. H. & Epstein, M. A. (1985). In vitro analysis of the Epstein-Barr virus: host balance in long-term renal allograft recipients. International Journal of Cancer 35, 45-49.