Randomised crossover comparison of the pharmacokinetic profiles of two sustained release morphine sulfate formulations in patients with cancer-related pain

Clinical Drug Investigation

Volumn 14, Issue SUPPL. 1, 1997, Pages 28-33

  De Bernardi, Mario ^a,b   De Bernardi, Francesca ^a   Colombo, Paolo ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b Cattedra di Geriatria   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

M ESLON; MORPHINE SULFATE; OPIATE; UNCLASSIFIED DRUG;

ADULT; AGED; BIOEQUIVALENCE; CANCER PAIN; CLINICAL ARTICLE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DROWSINESS; DRUG BLOOD LEVEL; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESTLESSNESS; SUSTAINED RELEASE PREPARATION; URINE RETENTION; XEROSTOMIA;

EID: 0030813209     PISSN: 11732563     EISSN: None     Source Type: Journal    
DOI: 10.2165/00044011-199700141-00007     Document Type: Conference Paper

References (6)

1. World Health Organization: Pain and cancer. Geneva: WHO Official Publication, 1988
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3. Walsh TD, MacDonald N, Bruera E, et al. A controlled study of sustained-release morphine sulfate tablets in chronic pain from advanced cancer. Am J Clin Oncol (CCT) 1992; 15 (3): 268-72
4. Walsh TD, Saunders CM. Oral morphine for relief of chronic pain from cancer. N Engl J Med 1981; 305: 1417
5. Tamburini M, Selmi S, De Conno F, et al. Semantic descriptors of pain. Pain 1987; 29 (2): 187-93
6. De Bernardi M, Contos S, Tripodi AS, et al. Bioequivalence study of two different sustained release morphine formulations. Acta Toxicol Ther 1993; 14 (4): 209-28