Randomized comparison of G-CSF + GM-CSF vs G-CSF alone for mobilization of peripheral blood stem cells: Effects on hematopoietic recovery after high-dose chemotherapy

Bone Marrow Transplantation

Volumn 20, Issue 11, 1997, Pages 921-930

  Spitzer, G ^a,b   Adkins, D ^a,c   Mathews, M ^a   Velasquez, W ^a   Bowers, C ^a   Dunphy, F ^a   Kronmueller, N ^a   Niemeyer, R ^a   McIntyre, W ^a   Petruska, P ^a  

^a S LOUIS UNIV HLTH SCIENCES CENTER   (United States)

^b LDS HOSPITAL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

G CSF; GM CSF; Stem cell mobilization

Indexed keywords

CD34 ANTIGEN; CYTOKINE; IMMUNOSUPPRESSIVE AGENT; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR;

ADULT; AGED; APHERESIS; ARTICLE; BONE MARROW BIOPSY; CELL COUNT; CLINICAL ARTICLE; CLINICAL TRIAL; CONDITIONING; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYOPRESERVATION; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG MEGADOSE; FEMALE; HEMATOPOIETIC SYSTEM; HOSPITALIZATION; HUMAN; LENGTH OF STAY; LYMPHATIC SYSTEM TUMOR; MALE; MOBILIZATION; MONONUCLEAR CELL; NEUTROPHIL; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; SOLID TUMOR; THROMBOCYTE COUNT;

EID: 0030813148     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1700999     Document Type: Article

References (51)

1. Brandt SJ, Peters WP, Atwater SK et al. Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone marrow transplantation. New Engl J Med 1988; 318: 869-876.
2. Neumnaitis J, Rabinowe SN, Singer JW et al. Recombinant granulocyte-macrophage colony-stimulating factor after autologous bone marrow transplant for lymphoid cancer: pooled results from three randomized double-blind, placebo controlled trials. New Engl J Med 1991; 324: 1773-1778.
3. Taylor KM, Jagannath S, Spitzer G et al. Recombinant human granulocyte colony-stimulating factor hastens granulocyte recovery after high-dose chemotherapy and autologous bone marrow transplantation in Hodgkin's disease. J Clin Oncol 1989; 7: 1791-1799.
4. Devereaux S, Linch DC, Gribben JG et al. GM-CSF accelerates neutrophil recovery after autologous bone marrow transplantation for Hodgkin's disease. Bone Marrow Transplant 1989; 4: 49-54.
5. Chao NJ, Schriber JR, Grimes K et al. Granulocyte colony-stimulating factor 'mobilized' peripheral blood progenitor cells accelerate granulocyte and platelet recovery after high dose chemotherapy. Blood 1993; 81: 2031-2035.
6. Gianni AM, Bregni M, Stern AS. Granulocyte-macrophage colony-stimulating factor to harvest circulating hemopoietic stem cells for autotransplantation. Lancet 1989; 2: 580-585.
7. Gianni AM, Bregni M, Siena S et al. Rapid and complete hemopoietic reconstitution following combined transplantation of autologous blood and bone marrow cells. A changing role for high dose chemo-radiotherapy. Hematol Oncol 1989; 7: 139-148.
8. Huan SD, Hester J, Spitzer G et al. Influence of mobilized peripheral blood cells on the hematopoietic recovery by autologous marrow and recombinant granulocyte-macrophage colony stimulating factor following high-dose cyclophosphamide, etoposide and cisplatin. Blood 1992; 79: 3388-3393.
9. Lobo F, Kessinger A, Landmark JD et al. Addition of peripheral blood stem cells collected without mobilization techniques to transplant autologous bone marrow did not hasten marrow recovery following myeloablative therapy. Bone Marrow Transplant 1991; 8: 389-392.
10. Peters WP, Rosner G, Ross M et al. Comparative effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF) on priming peripheral blood progenitor cells for use with autologous bone marrow after high-dose chemotherapy. Blood 1993; 7: 1709-1719.
11. Schwartzberg L, Birch R, Blanco R et al. Rapid and sustained hematopoietic reconstitution by peripheral blood stem cell infusion alone following high-dose chemotherapy. Bone Marrow Transplant 1993; 11: 369-374.
12. Spitzer G, Spencer V, Dunphy FR et al. Does peripheral blood further enhance hematopoietic recovery after autologous bone marrow transplantation and post transplantation recombinant growth factor? Int J Cell Cloning 1992; 10: 146-150.
13. Spitzer G, Deisseroth A, Ventura G et al. Use of recombinant human hematopoietic growth factors and autologous bone marrow transplantation to attenuate the neutropenic trough of high-dose therapy. Int J Cell Cloning 1990; 8: 249-259.
14. To LB, Dyson PG, Branford AL et al. Peripheral blood stem cells collected in very early remission produce rapid and sustained autologous hemopoietic reconstitution in acute nonlymphoblastic leukemia. Bone Marrow Transplant 1989; 2: 103-108.
15. To LB, Roberts MM, Haylock DN et al. Comparison of hematological recovery times and supportive care requirements of autologous recovery phase peripheral blood stem cell transplants, autologous bone marrow transplants and allogeneic bone marrow transplants. Bone Marrow Transplant 1992; 9: 277-284.
16. Blanco R, Birck R, Schwartzberg L et al. Rapid and sustained hematopoietic reconsitution by peripheral blood stem cell infusion alone following high-dose chemotherapy. Bone Marrow Transplant 1993; 11: 369-374.
17. Brugger W, Birken R, Bertz H et al. Peripheral blood progenitor cell mobilized by chemotherapy plus granulocyte-colony stimulating factor accelerate both neutrophil and platelet recovery after high-dose VP16, ifosfamide and cisplatin. Br J Haematol 1993; 84: 402-407.
18. Fukada M, Kojima S, Matsumoto K, Matsuyama T. Autotransplantation of peripheral blood stem cells mobilized by chemotherapy and recombinant human granulocyte colony-stimulating factor in childhood neuroblastoma and non-Hodgkin's lymphoma. Br J Haematol 1992; 80: 327-333.
19. Hohaus S, Goldschmidt H, Ehrhardt R, Haas R. Successful autografting following myeloablative conditioning therapy with blood stem cells mobilized by chemotherapy plus rhG-CSF. Exp Hematol 1993; 21: 508-514.
20. Kotasek D, Shepherd KM, Sage RE et al. Factors affecting blood stem cell collections following high-dose cyclophosphamide mobilization in lymphoma, myeloma in solid tumors. Bone Marrow Transplant 1992; 9: 11-17.
21. Pettengell R, Morgenstern GR, Woll PJ et al. Peripheral blood progenitor cell transplantation in lymphoma and leukemia using a single apheresis. Blood 1993; 82: 3770-3777.
22. Pettengall R, Demuynck H, Testa N. The engraftment capacity of peripheral blood progenitor cells mobilized with chemotherapy + G-CSF. Int J Cell Cloning 1992; 10: 59-61.
23. Pettengell R, Testa N, Swindell R et al. Transplantation potential of hematopoietic cells released into the circulation during rutine chemotherapy for non-Hodgkin's lymphoma. Blood 1993; 82: 2239-2248.
24. Ravagnani F, Siena S, Bregni M et al. Large-scale collection of circulating hematopoietic progenitors in cancer patients treated with high-dose cyclophosphamide and recombinant human GM-CSF. Eur J Cancer 1990; 5: 562-564.
25. Schwartzberg LS, Birch R, Hazelton B et al. Peripheral blood stem cell mobilization by chemotherapy with and without recombinant human granulocyte colony-stimulating factor. J Hematother 1992; 1: 317-327.
26. Schwartzberg L, Birch R, Blanco R et al. Rapid and sustained hematopoietic reconstitution by peripheral blood stem cell infusion alone following high-dose chemotherapy. Bone Marrow Transplant 1993; 11: 369-374.
27. Shimazaki C, Oku N, Ashihara E et al. Collection of peripheral blood stem cells mobilized by high-dose Ara-C plus VP-16 or aclarubicin followed by recombinant human granulocyte colony stimulating factor. Bone Marrow Transplant 1992; 10: 341-346.
28. Siena S, Bregni M, Brando L. Increase in peripheral blood megakaryocyre progenitors following cancer therapy with high dose cyclophosphamide and haematopoietic factor(s). Blood 1991; 79: 1583-1587.
29. Bensinger W, Singer J, Appelbaum F et al. Autologous transplantation with peripheral blood mononuclear cells collected after administration of recombinant granulocyte stimulating factor. Blood 1993; 81: 3158-3165.
30. Sheridan WP, Begley CG, Grigg A et al. Phase 11 study of autologous filgrastim (G-CSF)-mobilized peripheral blood progenitor cells to restore hemopoiesis after high-dose chemotherapy for lymphoid malignancies. Bone Marrow Transplant 1994; 14: 105-111.
31. Sheridan WP, Begley CG, Juttner CA et al. Effect on peripheral blood progenitor cells mobilized by filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet 1992; 339: 640-644.
32. Bolwell BJ, Fishleder A, Andresen WS et al. G-CSF primed peripheral blood progenitor cells in autologous bone marrow transplantation: parameters affecting bone marrow engraftment. Bone Marrow Transplant 1993; 12: 609-612.
33. Elias A, Mazanet R, Anderson K et al. GM-CSF mobilized peripheral blood stem cell autografts: the DFCI/BIH experience. Int J Cell Cloning 1992; 10: 149-153.
34. Abboud C, Liesveld J, Belanger T et al. Prospective randomized trial of four peripheral blood stem cell mobilization regimens, in lymphoma and breast cancer patients undergoing autologous marrow transplantation. Blood 1994; 84: 108a.
35. Begley CG, Basser R, Mansfield R et al. Randomized prospective study demonstrating a prolonged effect of SCF with G-CSF (filgrastim) on PBPC in untreated patients: early results. Blood 1994; 84: 25a.
36. Bolwell, Rosenfeld C, LeFever A et al. A phase II trial of G-CSF with or without SDZ ILE 964 (IL-3) for the mobilization of peripheral blood progenitor cells for autologous progenitor cell transplantation. Blood 1994; 84: 106a.
37. Engel H, Korbling M, Palmer J et al. Randomized trial of G-CSF alone versus sequential interleukin-3 and G-CSF treatment to peripheralize progenitor cells for apheresis and blood stem cell autotransplantation in patients with advanced stage breast cancer. Blood 1994; 84: 108a.
38. Huhn R, Yurkow E, Tushinski R et al. Priming with recombinant human interleukin-3 enhances the mobilization of blood progenitor cells by rh-granulocyte colony stimulating factor in normal volunteers. Blood 1994; 84: 541a.
39. Revel T, Appelbaum FR, Storb R et al. Effects of granulocyte colony-stimulating factor and stem cell factor, alone and in combination, on the mobilization of peripheral blood cells that engraft lethally irradiated dogs. Blood 1994; 83: 3795-3799.
40. + cells in apheresis products with different regimens. Bone Marrow Transplant 1994; 13: 479-485.
41. Bensinger WI, Longin K, Appelbaum FR et al. Peripheral blood stem cells (PBSCs) collected after recombinant granulocyte colony stimulating factor (rhG-CSF): an analysis of factors correlated with the tempo of engraftment after transplantation. Br J Haematol 1994; 87: 825-831.
42. + cells in pheresis harvests from patients mobilized by growth factors predict engraftment post-transplantation. Blood 1994; 84: 348a.
43. Siena S, Bregni M, Brando B et al. Flow cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients. Blood 1991; 2: 400-469.
44. + hematopoietic stem cells in the peripheral blood of high-dose cyclophosphamide treated patients: enhancement by intravenous recombinant human granulocyte macrophage colony stimulating factor. Blood 1989; 74: 1905-1914.
45. Weaver C, Birch R, Schwartzberg L et al. CD34 content of peripheral blood progenitor cells (PBPC) is the single most powerful predictor of recovery kinetics in patients receiving myeloablative high dose chemotherapy and PBPC infusion. Blood 1994; 84: 351a.
46. Klumpp TR, Mangan KM, Goldberg SL et al. Granulocyte colony-stimulating factor accelerates neutrophil engraftment following peripheral blood stem cell transplantation: a prospective, randomized trial. J Clin Oncol 1995; 13: 1323-1327.
47. Spitzer G, Adkins D, Spencer V et al. Randomized study of growth factors post peripheral blood stem cell transplant: neutrophil recovery is improved with modest clinical benefit. J Clin Oncol 1994; 12: 661-670.
48. Bot FJ, Van Eijk L, Schipper P et al. Synergistic effects between GM-CSF and G-CSF or M-CSF on highly enriched human marrow progenitor cells. Leukemia 1990; 4: 325-328.
49. + positive peripheral blood progenitor cells required for engraftment after myeloablative treatment for multiple myeloma. Blood 1994; 84: 207a.
50. Haas R, Mohle R, Fruhauf S et al. Patients characteristics associated with successful mobilizing and autografting of peripheral blood progenitor cells in malignant lymphomas. Blood 1994; 83: 3787-3794.
51. Moskowitz C, Stiff P, Gordon M et al. The influence of extensive prior chemotherapy on the mobilization of peripheral blood progenitor cells using stem cell factor (rhSCF) and filgrastim (rmetHuG-SCF) and on hematologic recovery post-cyclophosphamide. BCNU and VP-16 in patients with relapsed non-Hodgkin's lymphoma: an interim analysis. Blood 1994; 84: 107a.