The effect of basic fibroblast growth factor on coronary vascular tone in experimental hypercholesterolemia in vivo and in vitro

Coronary Artery Disease

Volumn 8, Issue 5, 1997, Pages 299-304

  Hasdai, David ^a   Mathew, Verghese ^a   Schwartz, Robert S ^a   Holmes Jr , David R ^a   Lerman, Amir ^a  

^a MAYO CLINIC   (United States)

Author keywords

Basic fibroblast growth factor; Coronary artery; Coronary blood flow; Endothelium; Hypercholesterolemia; Pig

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; BRADYKININ; CHOLESTEROL; PROSTAGLANDIN F2 ALPHA;

ANGIOGRAPHY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY DIAMETER; ARTERY ENDOTHELIUM; ARTICLE; BLOOD VESSEL TONE; CHOLESTEROL DIET; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY CONSTRICTION; CORONARY ARTERY DILATATION; DOPPLER FLOWMETRY; FEMALE; HYPERCHOLESTEROLEMIA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; PRIORITY JOURNAL;

EID: 0030812486     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-199705000-00007     Document Type: Article

References (52)

1. Follkman J, Klagsburn M: Angiogenic factors. Science 1987, 235:442-447.
2. Gospodarowicz D. Biological activities of fibroblast growth factors. Ann NY Acad Sci 1991, 638:1-8.
3. Friesel RE, Maciag T: Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction. FASEB J 1995, 9:919-925.
4. Lindner V, Reidy MA: Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study. Circ Res 1993, 73:589-595
5. Cheng GC, Libby P, Grodzinsky AJ, Lee RT: Induction of DNA synthesis by a single transient mechanical stimulus of human vascular smooth muscle cells. Role of fibroblast growth factor-2. Circulation 1996, 93:99-105.
6. Gajdusek CM. Carbon S: Injury-induced release of basic fibroblast growth factor from bovine aortic endothelium. J Cell Physiol 1989, 139:570-579.
7. Olson NE, Chao S, Linder V, Reidy MA: Intimal smooth muscle proliferation after balloon injury: the role of basic fibroblast growth factor. Am J Pathol 1992, 140:1017-1023.
8. Banai S, Jaklitsch MT, Casscells W, Shou M, Shrivastav S, Correa R. et al.: Effects of acidic fibroblast growth factor on normal and ischemic myocardium. Circ Res 1991, 69:76-85.
9. Luscher TF, Richard V, Tschdi M, Yang Z, Boulanger C: Endothelial control of vascular tone in large and small coronary arteries. J Am Coll Cardiol 1990, 15:519-527.
10. Van Benthuysen KM, McMurtry IF, Horowitz LD: Reperfusion after coronary occlusion in dogs impairs endothelium-dependent relaxation to acetylcholine and augments contractile reactivity in vitro. J Clin Invest 1987, 79:265-274.
11. Lerman A, Burnett JC Jr: Intact and altered endothelium in regulation of vasomotion. Circulation 1992, 86 (suppl 3):III12-III19.
12. Cuevas P, Carceller F, Ortega S, Zazo M, Nieto I, Gimenez-Gallego G: Hypotensive activity of fibroblast growth factor. Science 1991, 254:1208-1210.
13. Sellke FW, Wang SY, Friedman M, Harada K, Edelman ER, Grossman W, et al.: Basic FGF enhances endothelium-dependent relaxation of the collateral-perfused coronary microcirculation. Am J Physiol 1994, 267:H1303-H1311.
14. Unger EF, Banai S, Shou M, Lazarous DF, Jaclitsch MT, Scheinowitz M, et al.: Basic fibroblast growth factor enhances myocardial collateral blood flow in a canine model. Am J Physiol 1994, 266:H1588-H1595.
15. Lazarous DF, Scheinowitz M, Shou M, Hodge E, Rajanayagam MAS, Hunsberger S, et al.: Effects of chronic systemic administration of basic fibroblast growth factor on collateral development in the canine heart. Circulation 1995, 91:145-153.
16. Battler A, Scheinowitz M, Bor A, Hasdai D, Vered Z, Di Segni E, et al.: Intracoronary injection of basic fibroblast growth factor enhances angiogenesis in infarcted swine myocardium. J Am Coll Cardiol 1993, 22:2001-2006.
17. Uchida Y, Yanagisawa-Miwa A, Nakamura F, Yamada K, Tomaru T, Kimura K, et al.: Angiogenic therapy of acute myocardial infarction by intrapericardial injection of basic fibroblast growth factor and heparin sulfate: an experimental study. Am Heart J 1995, 130:1182-1188.
18. Brogi E, Winkles JA, Underwood R, Clinton SK, Alberts GF, Libby P: Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages. J Clin Invest 1993, 92:2408-2418.
19. Hughes SE, Crossman D, Hall PA: Expression of basic and acidic fibroblast growth factors and their receptor in normal and atherosclerotic human arteries. Cardiovasc Res 1993, 27: 1214-1219.
20. Flugelman FY, Virmani R, Correa R, Yu ZX, Farb A, Leon MB, et al: Smooth muscle cell abundance and fibroblast growth factors in coronary lesions of patients with nonfatal unstable angina. A clue to the mechanism of transformation from the stable to the unstable clinical state. Circulation 1993, 88:2493-2500.
21. Liau G, Winkles JA, Kuo L, Chilian WM: Dietary-induced atherosclerotic lesions have increased levels of acidic FGF mRNA and altered cytoskeletal and extracellular matrix mRNA expression. J Vasc Res 1993, 30:327-332.
22. Merkel LA, Bilder GC: Modulation of vascular reactivity by vasoactive peptides in aortic rings from hypercholesterolemic rabbits. Eur J Pharmacol 1992, 222:135-139.
23. Lerman A, Webster MW, Chesebro JH, Edwards WD, Wei CM, Fuster V, et al.: Circulating and tissue endothelin immunoreactivity in hypercholesterolemic pigs. Circulation 1993, 88:2923-2928.
24. Chester AH, O'Neil GS, Moncada S, Tadjkarimi S, Yacoub MH: Low basal and stimulated release of nitric oxide in atherosclerotic epicardial coronary arteries. Lancet 1990, 336:897-900.
25. Tomita Y, He Y, Uemura R, Takano H, Hoshino K, Kusama Y, et al.: A mechanism of elevated circulating level of basic FGF in patients with unstable angina [abstract]. J Am Coll Cardiol 1997, 29:229A.
26. Yanagisawa-Miwa Y, Uchida Y, Nakamura F, Tomaru T, Kido H, Kamijo T, et al.: Salvage of infarcted myocardium by angiogenic action of basic fibroblast growth factor. Science 1992, 257:1401-1403.
27. Harada K, Grossman W, Friedman M, Edelman ER, Prasad PV, Keighley CS, et al: Basic fibroblast growth improves myocardial function in chronically ischemic porcine hearts. J Clin Invest 1994, 94:623-630.
28. Asahara T, Bauters C, Zheng LP, Takeshita S, Bunting S, Ferrara N, et al:. Synergistic effects of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo. Circulation 1995, 92 (suppl 2):II365-II371.
29. Meurice T, Bauters C, Auffray JL, Vallet B, Hamon M, Valero F, et al.: Basic fibroblast growth factor restores endothelium-dependent responses after balloon injury of rabbit arteries. Circulation 1996, 93:18-22.
30. Doucette JW, Corl PD, Payne HM, Flynn AE, Goto M, Nassi M, et al.: Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation 1992, 85:1899-1911.
31. Bove AA, Holmes DR Jr, Owen RM, Bresnahan JF, Reeder GS, Smith HC, et al.: Estimation of the effects of angioplasty on coronary stenosis using quantitative video angiography. Cath Cardiovasc Diagn 1985, 11:5-16.
32. Ofili EO, Labovitz AJ, Kern MJ: Coronary flow velocity dynamics in normal and diseased arteries. Am J Cardiol 1993, 71:3D-9D.
33. Allain CC, Poon LS, Chan CSL, Richmond W, Fu PC: Enzymatic determination of total serum cholesterol. Clin Chem 1974, 20:470-475.
34. Mathew V, Cannan CR, Miller VM, Barber DA, Hasdai D, Schwartz RS, et al: Enhanced endothelin mediated coronary vasoconstriction and attenuated basal nitric oxide activity in experimental hypercholesterolemia. Circulation 1997, (in press).
35. Kent KC, Mii S, Harrington EO, Chang JD, Mallette S, Ware JA: Requirement for protein kinase C activation in basic fibroblast-induced human endothelial cell proliferation. Circ Res 1995, 77:231-238.
36. Ito A, Shimokawa H, Nakaike R, Fukai T, Sakata M, Takayanagi T, et al.: Role of protein kinase C-mediated pathway in the pathogenesis of coronary spasm in the swine model. Circulation 1994, 90:2425-2431.
37. 2+ sensitization. Am J Physiol 1995, 268:H301-H307.
38. Durante W, Knoll MH, Vanhoutte PM, Schafer AI: Endothelium-derived relaxing factor inhibits thrombin-induced platelet-aggregation by inhibiting platelet phospholipase C. Blood 1992, 79:110-116.
39. Lang D, Lewis MJ: Endothelium-derived relaxing factor inhibits the endothelin-1-induced increase in protein kinase C activity in rat aorta. Br J Pharmacol 1991, 104:139-144.
40. Creager MA, Cooke JP, Mendelsohn ME, Gallagher SJ, Coleman SM, Loscalzo J, et al.: Impaired vasodilation of forearm vessels in hypercholesterolemic humans. J Clin Invest 1990, 86:228-234.
41. Zeiher AM, Drexler H, Wollschager H, Just H: Modulation of coronary vasomotor tone in humans. Progressive endothelial dysfunction with different early stages of coronary atherosclerosis. Circulation 1991, 83:391-401.
42. Weidinger FF, McLenachan JM, Cybulsky MI, Gordon JB, Rennke HG, Hollenberg NK, et al.: Persistent dysfunction of regenerated endothelium after balloon angioplasty of rabbit iliac artery. Circulation 1990, 81:1667-1679.
43. Horrigan MCG, MacIsaac AI, Nicolini FA, Vince DG, Lee P, Ellis SG, et al.: Reduction in myocardial infarct size by basic fibroblast growth factor after temporal coronary occlusion in a canine model. Circulation 1996, 94:1927-1933.
44. Lerman A, Sandok EK, Hildebrand FL Jr, Burnett JC Jr: Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction. Circulation 1992, 85:1894-1898.
45. Cristiani C, Volpi D, Landonio A, Bertolero F: Endothelin-1 selective binding sites are downregulated by transforming growth factor-beta and upregulated by basic fibroblast growth factor in a vascular smooth muscle-derived cell line. J Cardiovasc Pharmacol 1994, 23:988-994.
46. Bonin PD, Leadley RJ Jr, Erickson LA: Growth factor-induced modulation of endothelin-1 binding to human smooth-muscle cells. J Cardiovasc Pharmacol 1993, 22 (suppl 8):S125-S127.
47. 22 in porcine coronary artery. Circulation 1990, 81:1654-1659.
48. Scherrer U, Randin D, Vollenweider P, Vollenweider L, Nicod P: Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 1994, 94:2511-2515.
49. Creager MA, Liang CS, Coffman JD: Beta adrenergic-mediated vasodilator response to insulin in the human forearm. J Pharmacol Exp Ther 1985, 235:709-714.
50. Mignatti P, Morimoto T, Rifkin DB: Basic fibroblast growth factor, a protein devoid of secretory signal sequence, is released by cells via a pathway independent of the endoplasmic reticulum-Golgi complex. J Cell Physiol 1992, 151:81-93.
51. Brothers TE, Robison JG, Elliott BM, Boggs JM, Frankel AE, Willingham MC: Upregulation of b-FGF receptor expression after carotid bypass. J Surg Res 1995, 58:28-32.
52. Hasdai D, Blumberg N, Battler A: The non-antithrombotic therapeutic potential of heparin and related heparinoids in cardiovascular diseases. Coronary Artery Dis 1994, 5:81-91.