3-Methoxynaltrexone, a selective heroin/morphine-6β-glucuronide antagonist

FEBS Letters

Volumn 412, Issue 1, 1997, Pages 35-38

  Brown, George P ^a   Yang, Ke ^a   King, Michael A ^a   Rossi, Grace C ^a   Leventhal, Liza ^a   Chang, Albert ^a   Pasternak, Gavril W ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Analgesia; Morphine; Mu receptor; Opioid; Opioid receptor

Indexed keywords

3 METHOXYNALTREXONE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; DELTA OPIATE RECEPTOR; DIAMORPHINE; DRUG METABOLITE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; KAPPA OPIATE RECEPTOR; MORPHINE; MORPHINE 6 ACETATE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR; N METHYLLEVALLORPHAN; NALOXONE BENZOYLHYDRAZONE; OPIATE AGONIST; OPIATE ANTAGONIST; RADIOLIGAND; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN HOMOGENATE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG BINDING SITE; DRUG SELECTIVITY; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MOUSE; NONHUMAN; OPIATE ADDICTION; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; SUBCUTANEOUS DRUG ADMINISTRATION;

ANALGESIA; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; HEROIN; MALE; MICE; MORPHINE; MORPHINE DERIVATIVES; NALTREXONE; NARCOTIC ANTAGONISTS; RECEPTORS, OPIOID, MU; TRANSFECTION; TRITIUM;

ANIMALIA;

EID: 0030811735     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00710-2     Document Type: Article

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