Comparison of aorta and pulmonary artery: II. LDL transport and metabolism correlate with susceptibility to atherosclerosis

Circulation Research

Volumn 81, Issue 3, 1997, Pages 346-354

  Schwenke, Dawn C ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Aorta; Atherosclerosis; LDL metabolism; LDL permeability; Pulmonary artery

Indexed keywords

LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTERY INTIMA; ARTERY MEDIA; ARTICLE; ATHEROSCLEROSIS; CELL MEMBRANE PERMEABILITY; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DISEASE PREDISPOSITION; HYPERCHOLESTEROLEMIA; LIPOPROTEIN METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PULMONARY ARTERY; RABBIT;

EID: 0030811035     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.81.3.346     Document Type: Article

References (68)

1. Duff GL, McMillan GC. Pathology of atherosclerosis. Am J Med. 1951;11:92-108.
2. Fischer GM, Swain ML, Cherian K. Increased vascular collagen and elastin synthesis in experimental atherosclerosis in the rabbit: variation in synthesis among major vessels. Atherosclerosis. 1980;35:11-20.
3. Chen M-F, Lee Y-T, Hsu H-C, Yeh P-C, Liau C-S, Huang P-C. Effects of dietary supplementation with fish oil on atherosclerosis and myocardial injury during acute coronary occlusion-reperfusion in diet-induced hypercholesterolemic rabbits. Int J Cardiol. 1992;35:323-332.
4. Sun YP, Zhu BQ, Sievers RE, Glantz SA, Parmley WW. Metoprolol does not attenuate atherosclerosis in lipid-fed rabbits exposed to environmental tobacco smoke. Circulation. 1994;89:2260-2265.
5. Child GV, Thurlbeck WM, Weigensberg BI. Severe pulmonary atherosclerosis in hypercholesterolemic rabbits. Arch Pathol. 1974; 98:47-50.
6. Zhu B-Q, Sievers RE, Sun Y-P, Isenberg WM, Parmley WW. Effect of lovastatin on suppression and regression of atherosclerosis in lipid-fed rabbits. J Cardiovasc Pharmacol. 1992;19:246-255.
7. Zhu B-Q, Smith DL, Sievers RE, Isenberg WM, Parmley WW. Inhibition of atherosclerosis by fish oil in cholesterol-fed rabbits. J Am Coll Cardiol. 1988;12:1073-1078.
8. Zhu B-Q, Sievers RE, Isenberg WM, Smith DL, Parmley WW. Regression of atherosclerosis in cholesterol-fed rabbits: effects of fish oil and verapamil. J Am Coll Cardiol. 1990;15:231-237.
9. Eckert H. Lung changes by experimentally induced cholesterol atheromatosis. Z Erkr Atmungsorgane. 1976;145:202-207.
10. Plump AS, Smith JD, Hayek T, Aalto-Setala K, Walsh A, Verstuyft JG, Rubin EM, Breslow JL. Severe hypercholesterolemia and atherosclerosis in apolipoprotein-E-deficient mice created by homologous recombination in ES cells. Cell. 1992;71:343-353.
11. Carew TE, Schwenke DC, Steinberg D, Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. Proc Natl Acad Sci U S A. 1987;84:7725-7729.
12. Shiomi M, Ito T, Watanabe Y, Tsujita Y, Kuroda M, Arai M, Fukami M, Fukushige J, Tamura A. Suppression of established atherosclerosis and xanthomas in mature WHHL rabbits by keeping their serum cholesterol levels extremely low: effect of pravastatin sodium in combination with cholestyramine. Atherosclerosis. 1990;83:69-80.
13. Chobanian AV, Haudenschild CC, Nickerson C, Drago R. Antiatherogenic effect of captopril in the Watanabe heritable hyperlipidemic rabbit. Hypertension. 1990;15:327-331.
14. Chobanian AV, Haudenschild CC, Nickerson C, Hope S. Trandolapril inhibits atherosclerosis in the Watanabe heritable hyperlipidemic rabbit. Hypertension. 1992;20:473-477.
15. Chobanian AV, Lichtenstein AH, Nilakhe V, Haudenschild CC, Drago R, Nickerson C. Influence of hypertension on aortic atherosclerosis in the Watanabe rabbit. Hypertension. 1989;14:203-209.
16. Schwenke DC. Comparison of aorta and pulmonary artery, I: early cholesterol accumulation and relative susceptibility to atheromatous lesions. Circ Res. 1997;81:338-345.
17. Newman HAI, Zilversmit DB. Quantitative aspects of cholesterol flux in rabbit atheromatous lesions. J Biol Chem. 1962;237:2078-2084.
18. Christensen S. Transfer with labeled cholesterol across the aortic intimal surface of normal and cholesterol-fed cockerels. J Atheroscler Res. 1964;4:151-160.
19. Zilversmit DB. Cholesterol flux in the atherosclerotic plaque. Ann NY Acad Sci. 1968;149:710-724.
20. Dayton S, Hashimoto S. Recent advances in molecular pathology: a review: cholesterol flux and metabolism in arterial tissue and in atheroma. Exp Mol Pathol. 1970;13:253-268.
21. Christensen S, Stender S, Nyvad O, Bagger H. In vivo fluxes of plasma cholesterol, phosphatidylcholine and protein into mini-pig aortic and pulmonary segments. Atherosclerosis. 1982;41:309-319.
22. Tompkins RG. Quantitative analysis of blood vessel permeability of squirrel monkeys. Am J Physiol. 1991;260:H1194-H1204.
23. 125I-low density lipoprotein uptake in selected tissues of the squirrel monkey by quantitative autoradiography. Am J Pathol. 1988;132:526-542.
24. Tompkins RG, Yarmush ML, Schnitzer JJ, Colton CK, Smith KA, Stemerman MB. Low-density lipoprotein transport in blood vessel walls of squirrel monkeys. Am J Physiol. 1989;257:H452-H464.
25. Schwenke DC, St Clair RW. Influx, efflux, and accumulation of LDL in normal arterial areas and atherosclerotic lesions of White Carneau pigeons with naturally occurring and cholesterol-aggravated aortic atherosclerosis. Arterioscler Thromb. 1993;13:1368-1381.
26. Schwenke DC. Gender differences in intima-media permeability to low density lipoprotein at atherosclerosis-prone aortic sites in rabbits: lack of effect of 17beta-estradiol. Arterioscler Thromb Vasc Biol. In press.
27. Schwenke DC, Carew TE. Quantification in vivo of increased LDL content and rate of LDL degradation in normal rabbit aorta occurring at sites susceptible to early atherosclerotic lesions. Circ Res. 1988;62:699-710.
28. Schwenke DC, Carew TE. Initiation of atherosclerotic lesions in cholesterol-fed rabbits, I: focal increases in arterial LDL concentration precede development of fatty streak lesions. Arteriosclerosis. 1989;9:895-907.
29. Lever MJ, Jay MT. Albumin and Cr-EDTA uptake by systemic arteries, veins, and pulmonary artery of rabbit. Arteriosclerosis. 1990;10:551-558.
30. Schwenke DC. Selective increase in cholesterol at atherosclerosis-susceptible aortic sites after short-term cholesterol feeding. Arterioscler Thromb Vasc Biol. 1995;15:1928-1937.
31. Terpstra AHM, Woodward CJH, Sanchez-Muniz FJ. Improved techniques for the separation of serum lipoproteins by density gradient ultracentrifugation: visualization by prestaining and rapid separation of serum lipoproteins from small volumes of serum. Anal Biochem. 1981;111:149-157.
32. Havel RJ, Eder HA, Bragdon JH. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J Clin Invest. 1955;34:1345-1353.
33. Schwenke DC, Carew TE. Initiation of atherosclerotic lesions in cholesterol-fed rabbits, II: selective retention of LDL vs. selective increases in LDL permeability in susceptible sites of arteries. Arteriosclerosis. 1989;9:908-918.
34. Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem. 1977;83:346-356.
35. Carew TE, Pittman RC, Marchand ER, Steinberg D. Measurement in vivo of irreversible degradation of low density lipoprotein in the rabbit aorta: predominance of intimal degradation. Arteriosclerosis. 1984;4:214-224.
36. Fraker PJ, Speck JC Jr. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril. Biochem Biophys Res Commun. 1978;80:849-857.
37. Pittman RC, Carew TE, Glass CK, Green SR, Taylor CA Jr, Attie AD. A radioiodinated, intracellularly trapped ligand for determining the sites of plasma protein degradation in vivo. Biochem J. 1983;212:791-800.
38. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 1970;227:680-685.
39. 125I-tyramine cello-biose-labeled low density lipoprotein is greater in the atherosclerosis-susceptible region of White Carneau pigeon aorta and further enhanced once atherosclerotic lesions develop. Arterioscler Thromb. 1992;12:446-460.
40. Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem. 1957;226:497-509.
41. Noble RP. Electrophoretic separation of plasma lipoproteins in agarose gel. J Lipid Res. 1968;9:693-700.
42. Wiklund O, Carew TE, Steinberg D. Role of the low density lipoprotein receptor in penetration of low density lipoprotein into rabbit aortic wall. Arteriosclerosis. 1985;5:135-141.
43. Lipid Research Clinics Program. Manual of Laboratory Operations: Lipid and Lipoprotein Analysis. Washington, DC: US Government Printing Office, 1982. US Dept of Health, Education, and Welfare publication NIH 75-629.
44. Winer BJ. Statistical Principles in Experimental Design. 2nd ed. New York, NY: McGraw-Hill Publishing Co; 1971.
45. Snedecor GW, Cochran WG. Statistical Methods. 6th ed. Ames, Iowa: The Iowa State University Press; 1979:3-593.
46. Wallenstein S, Zucker CL, Fleiss JL. Some statistical methods useful in circulation research. Circ Res. 1980;47:1-9.
47. Khouw AS, Parthasarathy S, Witztum JL. Radioiodination of low density lipoprotein initiates lipid peroxidation: protection by use of antioxidants. J Lipid Res. 1993;34:1483-1496.
48. Leung DYM, Glagov S, Mathews MB. Elastin and collagen accumulation in rabbit ascending aorta and pulmonary artery trunk during postnatal growth: correlation of cellular synthetic response with medial tension. Circ Res. 1977;41:316-323.
49. Shafi S, Palinski W, Born GVR. Comparison of uptake and degradation of low density lipoproteins by arteries and veins of rabbits. Atherosclerosis. 1987;66:131-138.
50. Berceli SA, Borovetz HS, Sheppeck RA, Moosa HH, Warty VS, Armany MA, Herman IM. Mechanisms of vein graft atherosclerosis - LDL metabolism and endothelial actin reorganization. J Vasc Surg. 1991;13:336-347.
51. Walton KW, Dunkerley DJ, Johnson AG, Khan MK, Morris C, Watts RB. Investigation by immunofluorescence of arterial lesions in rabbits on two different lipid supplements and treated with pyridinol carbamate. Atherosclerosis. 1976;23:117-139.
52. Bratzler RL, Chisolm GM, Colton CK, Smith KA, Lees RS. The distribution of labeled low-density lipoproteins across the rabbit thoracic aorta in vivo. Atherosclerosis. 1977;28:289-307.
53. Stender S, Hjelms E. In vivo transfer of cholesteryl ester from high and low density plasma lipoproteins into human aortic tissue. Arteriosclerosis. 1988;8:252-262.
54. Fry DL. Mass transport, atherogenesis, and risk. Arteriosclerosis. 1987;7:88-100.
55. Nordestgaard BG, Hjelms E, Stender S, Kjeldsen K. Different efflux pathways for high and low density lipoproteins from porcine aortic intima. Arteriosclerosis. 1990;10:477-485.
56. Roach MR, Fletcher J, Cornhill JF. The effect of the duration of cholesterol feeding on the development of sudanophilic lesions in the rabbit aorta. Atherosclerosis. 1976;25:1-11.
57. Roach MR, Fletcher J, Alterations in distribution of sudanophilic lesions in rabbits after cessation of a cholesterol-rich diet. Atherosclerosis. 1979;32:1-10.
58. Roach MR, Cornhill JF, Fletcher J. A quantitative study of the development of sudanophilic lesions in the aorta of rabbits fed a low-cholesterol diet for up to six months. Atherosclerosis. 1978;29:259-264.
59. Kratky RG, Ivey J, Rogers KA, Daley S, Roach MR. The distribution of fibro-fatty atherosclerotic lesions in the aortae of casein- and cholesterol-fed rabbits. Atherosclerosis. 1993;99:121-131.
60. Cornhill JF, Roach MR. A quantitative study of the localization of atherosclerotic lesions in the rabbit aorta. Atherosclerosis. 1976;23:489-501.
61. Daley SJ, Herderick EE, Cornhill JF, Rogers KA. Cholesterol-fed and casein-fed rabbit models of atherosclerosis, 1: differing lesion area and volume despite equal plasma cholesterol levels. Arterioscler Thromb. 1994;14:95-104.
62. Zeindler CM, Kratky RG, Roach MR. Quantitative measurements of early atherosclerotic lesions on rabbit aortae from vascular casts. Atherosclerosis. 1989;76:245-255.
63. Quinn MT, Parthasarathy S, Fong LG, Steinberg D. Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis. Proc Natl Acad Sci U S A. 1987;84:2995-2998.
64. Kume N, Cybulsky MI, Gimbrone MA, Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest. 1992;90:1138-1144.
65. Kim JA, Territo MC, Wayner E, Carlos TM, Parhami F, Smith CW, Haberland ME, Fogelman AM, Berliner JA. Partial characterization of leukocyte binding molecules on endothelial cells induced by minimally oxidized LDL. Arterioscler Thromb. 1994;14:427-433.
66. Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM. Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci U S A. 1990;87:5134-5138.
67. Rosenfeld ME, Khoo JC, Miller E, Parthasarathy S, Palinski W, Witztum JL. Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts. J Clin Invest. 1991;87:90-99.
68. Hurt-Camejo E, Camejo G, Rosengren B, Lopez F, Ahlstrom C, Fager G, Bondjers G. Effect of arterial proteoglycans and glycosaminoglycans on low density lipoprotein oxidation and its by human macrophages and arterial smooth muscle cells. Arterioscler Thromb. 1992;12:569-583.