A novel compound, 1,1-dimethyl-5-(1-hydroxypropyl)-4,6,7-trimethylindan, is an effective inhibitor of the tet(K) gene-encoded metal-tetracycline/H+ antiporter of Staphylococcus aureus

FEBS Letters

Volumn 412, Issue 2, 1997, Pages 337-340

  Hirata, Takahiro ^a,b   Wakatabe, Rumi ^b   Nielsen, Joergen ^c   Someya, Yuichi ^a   Fujihira, Erika ^a   Kimura, Tomomi ^a   Yamaguchi, Akihito ^a  

^a OSAKA UNIVERSITY   (Japan)

^b NIPPON ROCHE RESEARCH CENTER   (Japan)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Antiporter; Ro 07 3149; Staphyloccus aureus; TetK; Tetracycline

Indexed keywords

ANTIPORTER; INDAN DERIVATIVE; RO 07 3149; TETRACYCLINE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; ESCHERICHIA COLI; MEMBRANE VESICLE; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANTIPORTERS; BACTERIAL PROTEINS; CARBON RADIOISOTOPES; HYDROGEN-ION CONCENTRATION; INDANS; KINETICS; METHYLAMINES; STAPHYLOCOCCUS AUREUS; TETRACYCLINE; TRITIUM;

ESCHERICHIA COLI; STAPHYLOCCUS; STAPHYLOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 0030810738     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00796-5     Document Type: Article

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