Functional ablation of afferent nerves aggravates dextran sulphate sodium-induced colonic damage in rats

Journal of Gastroenterology and Hepatology (Australia)

Volumn 12, Issue 11, 1997, Pages 698-702

  Domek, Matthew J ^a   Blackman, Edward I ^a   Kao, John ^a   Zhang, Xiang Y ^a   Iwata, Fumihiro ^a   Seno, Kyoji ^a   Leung, Felix W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Afferent nerves; Capsaicin; Diarrhoea

Indexed keywords

CAPSAICIN; DEXTRAN SULFATE;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; COLITIS; COLON INJURY; COLON MUCOSA; CONTROLLED STUDY; DIARRHEA; HISTOLOGY; MALE; MORTALITY; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE;

EID: 0030810302     PISSN: 08159319     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1746.1997.tb00355.x     Document Type: Article

References (22)

1. Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 1990; 98: 694-702.
2. Zijlstra FJ, Garrelds IM, van Dijk AP, Wilson JH. Experimental colitis in mice: effects of olsalazine on eicosanoid production in colonic tissue. Agents Actions 1992; Spec. No: C76-8.
3. Kishimoto S, Kobayashi H, Shimizu S et al. Changes of colonic vasoactive intestinal peptide and cholinergic activity in rats with chemical colitis. Dig. Dis. Sci. 1992; 37: 1729-37.
4. Yamada M, Ohkusa T, Okayasu I. Occurrence of dysplasia and adenocarcinoma after experimental chronic ulcerative colitis in hamsters induced by dextran sulphate sodium. Gut 1992; 33: 1521-7.
5. van Dijk AP, McCafferty DM, Wilson JH, Zijlstra FJ. 15-Hydroxy-eicosatetraenoic acid has minor antiinflammatory properties in colitis. Agents Actions 1993; 38 Spec. No: C120-1.
6. Murthy SN, Cooper HS, Shim H, Shah RS, Ibrahim SA, Sedergran DJ. Treatment of dextran sulfate sodium-induced murine colitis by intracolonic cyclosporin. Dig. Dis. Sci. 1993; 38: 1722-34.
7. Tamaru T, Kobayashi H, Kishimoto S, Kajiyama G, Shimamoto F, Brown WR. Histochemical study of colonic cancer in experimental colitis of rats. Dig. Dis. Sci. 1993; 38: 529-37.
8. Yamashita S. Studies on changes of colonic mucosal PGE2 levels and tissue localization in experimental colitis. Gastroenterol. Jpn. 1993; 28: 224-35.
9. Cooper HS, Murthy SN, Shah RS, Sedergran DJ. Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab. Invest. 1993; 69: 238-49.
10. Dieleman LA, Ridwan BU, Tennyson GS, Beagley KW, Bucy RP, Elson CO. Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology 1994; 107: 1643-52.
11. Iwanaga T, Hoshi O, Han H, Fujita T. Morphological analysis of acute ulcerative colitis experimentally induced by dextran sulfate sodium in the guinea pig: some possible mechanisms of cecal ulceration. J. Gastroenterol. 1994; 29: 430-8.
12. Domek MJ, Iwata F, Blackman EI et al. Anti-neutrophil serum attenuates dextran sulfate sodium-induced colonic damage in rats. Scand. J. Gastroenterol. 1995; 30: 1089-94.
13. Holzer P, Sametz W. Gastric mucosal protection against ulcerogenic factors in the rat mediated by capsaicin-sensitive afferent neurons. Gastroenterology 1986; 91: 975-81.
14. Leung FW. Primary sensory nerves mediate in part the protective mesenteric hyperemia after intraduodenal acidification in rats. Gastroenterology 1993; 105: 1737-45.
15. Leung FW. Role of capsaicin-sensitive afferent nerves in mucosal injury and injury-induced hyperemia in rat colon. Am. J. Physiol. 1992; 262: G332-7.
16. Zipser RD, Nast CC, Lee M, Kao HW, Duke R. In vivo production of leukotriene B4 and leukotriene C4 in rabbit colitis. Gastroenterology 1987; 92: 33-9.
17. Onderdonk AB, Hermos JA, Dzink JL, Barlett JG. Protective effect of metronidazole in experimental ulcerative colitis. Gastroenterology 1978; 74: 521-6.
18. Buck SH, Walsh JH, Yamamura HI, Burks TF. Neuropeptides in sensory neurons. Life Sci. 1982; 30: 1857-66.
19. Yonei Y, Holzer P, Guth PH. Laparotomy-induced gastric protection against ethanol injury is mediated by capsaicin-sensitive sensory neurons. Gastroenterology 1990; 99: 3-9.
20. Gamse R, Leeman SE, Holzer P, Lembeck F. Differential effects of capsaicin on the content of somatostatin, substance P, and neurotensin in the nervous system of the rat. Naunyn Schmiedeberg's Arch. Pharmacol. 1981; 317: 140-8.
21. Sternini C, Reeve JR Jr, Brecha N. Distribution and characterization of calcitonin gene-related peptide immunoreactivity in the digestive system of normal and capsaicin-treated rats. Gastroenterology 1987; 93: 852-62.
22. Gamse R. Capsaicin and nociception in the rat and mouse. Naunyn Schmiedeberg's Arch. Pharmacol. 1982; 320: 205-16.