Analysis of TH1 and TH2 cytokine production in low grade B cell gastric MALT-type lymphomas stimulated in vitro with Helicobacter pylori

Journal of Clinical Pathology

Volumn 50, Issue 11, 1997, Pages 957-959

  Hauer, A C ^a   Finn, T M ^b   MacDonald, T T ^a   Spencer, J ^c   Isaacson, P G ^b  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Cytokines; Helicobacter pylori; Lymphoma; Stomach

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 5;

ARTICLE; B CELL LYMPHOMA; CANCER GRADING; CONTROLLED STUDY; HELICOBACTER PYLORI; HELPER CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LYMPHOMA; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA; PRIORITY JOURNAL; SALIVARY GLAND TUMOR; STOMACH LYMPHOMA; THYROID TUMOR;

EID: 0030809797     PISSN: 00219746     EISSN: None     Source Type: Journal    
DOI: 10.1136/jcp.50.11.957     Document Type: Article

References (10)

1. Wotherspoon AC, Doglioni C, Diss TC, Pan L, Moschini A, de Boni M, et al. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue following eradication of Helicobacter pylori. Lancet 1993;342:575-7.
2. Hussell T, Isaacson PG, Crabtree JE, Spencer J. The response of cells from low-grade B-cell gastric lymphomas of mucosa associated lymphoid tissue to Helicobacter pylori. Lancet 1993;342:571-4.
3. Hussell T, Isaacson PG, Crabtree JE, Spencer J. Helicobacter pylori-specific tumour- infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue. J Pathol 1996;178:122-7.
4. Karttunen R, Karttunen T, Ekre H-P T, MacDonald TT. Interferon gamma and interleukin 4 secreting cells in the gastric antrum in Helicobacter pylori positive and negative gastritis. Gut 1995;36:341-5.
5. D'Elios MM, Manghetti M, De Carli M, Costa F, Baldari CT, Burroni D, et al. T helper effector 1 cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J Immunol 1997;158:962-7.
6. Hussell T, Isaacsan PG, Spencer J. Proliferation and differentiation of tumour cells from B-cell lymphoma of mucosa-associated lymphoid tissue in vitro. J Pathol 1993; 169:221-7.
7. Petersen GL. A simplification of the protein assay method of Lowry et al which is more generally applicable. Anal Biochem 1987;83:346-56.
8. Hauer AC, Breese EJ, Walker-Smith JA, MacDonald TT. The frequency of cells secreting interferon-γ, IL-4, IL-5 and IL-10 in the blood and duodenal mucosa of children with cow's milk hypersensitivity. Paediatr Res. [In press.]
9. Defrance T, Aubry J-P, Vanbervliet B, Banchereau J. Human interferon-γ acts as a B cell growth factor in the anti-IgM antibody co-stimlatory assay but has no direct B cell differentiation activity. J Immunol 1986;137:3861-7.
10. Di Tommaso A, Xiang Z, Bugnoli M, Pileri P, Figura N, Bayeli PF, et al. Helicobacter pylori specific CD4+ T-cell clones from peripheral blood and gastric biopsies. Infect Immun 1995;63:1102-12.