Thiol agents potentiate glyceryl trinitrate mediated relaxation of rabbit taenia coli: Evidence for thiol-dependent biotransformation

Canadian Journal of Physiology and Pharmacology

Volumn 75, Issue 7, 1997, Pages 807-811

  Hussain, Aman S ^a   Abu Zahra, Tawfic N ^a   Brien, James F ^a   Marks, Gerald S ^a   Nakatsu, Kanji ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

Biotransformation; Cysteine; Glyceryl trinitrate; Methionine; Sulhydryl

Indexed keywords

ACETYLCYSTEINE; CYSTEINE; GLYCERYL TRINITRATE; METHIONINE; THIOL DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; COLON TENIA; CONTROLLED STUDY; DRUG SENSITIVITY; NONHUMAN; PRIORITY JOURNAL; RABBIT; SMOOTH MUSCLE RELAXATION; STEREOSPECIFICITY;

EID: 0030809614     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y97-092     Document Type: Article

References (2)

1. Bauer, J. A., and Fung, H.L. 1996. Specific binding of nitre-glycerin to coronary artery microsomes. Biochem. Pharmacol. 52(4): 619-625.
2. Bennett, B.M., McDonald, B.J., Nigam, R., and Simon, C.W. 1994. Biotransformation of organic nitrates and vascular smooth muscle function. Trends Pharmacol. Sci. 15: 245-249.