Relation between free fatty acid and acyl-CoA concentrations in rat brain following decapitation

Neurochemical Research

Volumn 22, Issue 7, 1997, Pages 759-765

  Deutsch, Joseph ^b   Rapoport, S I ^a   Purdon, A David ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Acyl CoA; Arachidonic acid; Brain; Docosahexaenoic acid; Fatty acids; Ischemia; Phospholipid; Rats; Stroke

Indexed keywords

ACYL COENZYME A; ARACHIDONIC ACID; DOCOSAHEXAENOIC ACID; FATTY ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; DECAPITATION; EXPERIMENTAL MODEL; GAS CHROMATOGRAPHY; LIPID ANALYSIS; LIPID COMPOSITION; MALE; NEUROCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE; THIN LAYER CHROMATOGRAPHY;

ACYL COENZYME A; ANIMALS; BRAIN; BRAIN ISCHEMIA; FATTY ACIDS, NONESTERIFIED; HUMANS; MALE; MICROWAVES; PHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030809527     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022030306359     Document Type: Article

References (30)

1. Rapoport, S. I., Lust, W. D., and Fredericks, W. R. 1986. Effects of hypoxia on rat brain metabolism: unilateral in vivo carotid infusion. Exp. Neurobiol. 91, 319-330.
2. Farooqui, A. A., and Horrocks, L. A. 1991. Excitatory amino acid receptors, neural membrane phospholipid metabolism and neurological disorders. Brain Res. Rev. 16:171-191.
3. Siesjö, B. K. 1992. Pathophysiology and treatment of focal cerebral ischemia. J. Neurosurg. 77:169-184.
4. Choi, D. W. 1990. Methods for antagonizing glutamate neurotoxicity. Cerebrovascular and Brain Metabolism Rev. 2:105-147.
5. Birkle, D. L. 1992. Reciprocal regulation of fatty acid release in the brain by GABA and glutamate in Neurobiology of Essential Fatty Acids (Bazan N. G., ed.) pp. 57-71. Plenum Press, New York.
6. Bazan, N. G. 1970. Effects of ischemia and electroconvulsive shock on free fatty acid pool in the brain. Biochim. Biophys. Acta 218:1-10.
7. Bazan, N. G. 1976. Free arachidonic acid and other lipids in the nervous system during early ischemia and after electroshock, in Advances in Experimental Medicine and Biology, Vol. 72: Function and Metabolism of Phospholipids in the Central and Peripheral Nervous System (Porcellati G., Amaducci, L., and Galli, C., eds), pp. 317-335. Plenum Press, New York/London.
8. Sun, G. Y., Lu, F. L., Lin, S. E., and Ko, M. R. 1992. Decapitation ischemia-induced release of free fatty acids in mouse brain. Mol Cell Neuropathol. 17:39-50.
9. Reddy, T. S., and Bazan, N. G. 1987. Arachidonic acid, stearic acid, and diacylglycerol accumulation correlates with the loss of phosphatidylinositol 4,5-bisphosphate in cerebrum 2 seconds after electroconvulsive shock: complete reversion of changes 5 minutes after stimulation. J. Neurosci. Res. 18:449-455.
10. Ikeda, M., Yoshida, S., Busto, R., Santiso, M., and Ginsberg, M. D. 1986. Polyphosphoinositides as a probable source of brain free fatty acids accumulated at the onset of ischemia. J. Neurochem. 47:123-132.
11. Lee, C., and Hajra, A. K. 1991. Molecular species of diacylglycerols and phosphoglycerides and the postmortem changes in the molecular species of diacylglycerols in rat brains. J. Neurochem. 56:370-379.
12. Kumar, R., Harvey, S., Kester, N., Hanahan, D., and Olson, M. 1988. Production and effects of platelet-activating factor in the rat brain. Biochim. Biophys. Acta 963:375-383.
13. Birkle, D. L., Kurian, P., Braquet, P., and Bazan, N. G. 1988. Platelet-activating factor antagonist BN 52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock. J. Neurochem. 51:1900-1905.
14. Edgar, A. D., Strosznajder, J., and Horrocks, L. A. 1982. Activation of ethanolamine phospholipase A2 in brain during ischemia. J. Neurochem. 39:1111-1116.
15. MacDonald, J. I. S, and Sprecher, H. 1991. Phospholipid fatty acid remodeling in mammalian cells. Biochim. Biophys. Acta 1084:105-121.
16. Waku, K. 1992. Origins and fates of fatty acyl-CoA esters. Biochim. Biophys. Acta 1124:101-111.
17. Rehncrona, S., Westerberg, E., Akesson, B., and Siesjö, B. K. 1982. Brain cortical fatty acids and phospholipids during and following complete and severe incomplete ischemia. J. Neurochem. 38:84-93.
18. Yoshida, S., Ikeda, M., Busto, R., Santiso, M., Martinez, E., and Ginsberg, M. D. 1986. Cerebral phosphoinositide, triacylglycerol, and energy metabolism in reversible ischemia:origin and fate of free fatty acids. J. Neurochem. 47:744-757.
19. Ikeda, M., Busto, R., Yoshida, S., Santiso, M., Martinez, E., and Ginsberg, M. D. 1988. Cerebral phosphoinositide, triacylglycerol and energy metabolism during severe hypoxia and recovery. Brain Research 459:344-350.
20. Deutsch, J., Grange, E., Rapoport, S. I., and Purdon, A. D. 1994. Isolation and quantitation of acyl-CoA esters in brain tissue by solid phase extraction. Analytical Biochem. 220:321-23.
21. Okuyama, H., Lands, W. E. M., Christie, W. W., and Gunstone, F. D. 1969. Selective transfer of cyclopropane acids by acyl-coenzyme A:phospholipid acyltransferase. J. Biol. Chem. 244, 6514-6519.
22. 3H]arachidonate in the anesthetized rat J. Neurochem. 63:727-736.
23. Folch, J., Lees, M., and Stanley, G. H. S. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226, 497-509.
24. Begun, J. M. 1985. Newman-Keuls Procedure in Encyclopaedia of Statistical Sciences, pp 200-201.
25. Robinson, P. J., Noronha, J., DeGeorge, J. J., Freed, L. M., Nariai, T., and Rapoport, S. I. 1992. A quantitative method for measuring regional in vivo fatty-acid incorporation into and turnover within brain phospholipids: review and critical analysis. Brain Res. Rev. 17:187-214.
26. Rosendal, J., and Knudsen, J. 1992. A fast and versatile method for extraction and quantitation of long-chain acyl-CoA esters from tissue:content of individual long-chain acyl-CoA esters in various tissues from fed rats. Analytical Biochem. 207:63-67.
27. Reddy, T. S., and Bazan, N. G. 1983. Kinetic properties of arachidonoyl-Coenzyme A synthetase in rat brain microsomes. Arch. Biochem. Biophys. 226:125-133.
28. 14C]docosahexaenoic acid substrate. Eur. J. Biochem. 145:21-29.
29. Laposata, M., Reich, E. L., and Majerus, P. W. 1985. Arachidonoyl-CoA Synthetase. Separation from nonspecific acyl-CoA synthetase and distribution in various cells and tissues. J. Biol. Chem. 260:11016-11020.
30. Mandings, S., Hummel, R., Rawn, S., Jensen, G., Andreison, P. H., Gregersen, N., Knudsen, J., and Kristiansen, K. 1992. Acyl-CoA binding protein/diazepam-binding inhibitor gene and pseudogenes. A typical housekeeping gene family. J. Mol Biol. 228: 1011-1022.