Toxicity of Subacute Intravenous Manganese Chloride Administration in Beagle Dogs

Toxicologic Pathology

Volumn 25, Issue 4, 1997, Pages 344-350

  Khan, K Nasir ^a   Andress, James M ^a   Smith, Peter F ^a  

^a PFIZER INC   (United States)

Author keywords

Cardiotoxicity; clinical pathology; hepatotoxicity; histopathology; manganese chloride; manganese complexes; safety assessment

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; LIVER ENZYME; MANGANESE CHLORIDE; NUCLEAR MAGNETIC RESONANCE IMAGING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOTOXICITY; CONTROLLED STUDY; DOSE LIVER FUNCTION RELATION; DOSE TIME EFFECT RELATION; DRUG SAFETY; HISTOPATHOLOGY; HYPOTENSION; LIVER NECROSIS; MALE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTHROMBIN TIME; TOXICITY TESTING;

ANIMALS; BLOOD CHEMICAL ANALYSIS; BODY WEIGHT; CARDIOVASCULAR SYSTEM; CHLORIDES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; INFUSIONS, INTRAVENOUS; LIVER; MALE; MANGANESE COMPOUNDS; MANGANESE POISONING; SURVIVAL;

ANIMALIA; CANIS FAMILIARIS;

EID: 0030809509     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339702500402     Document Type: Article

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