Molecular cloning of the dog β1 and β2 adrenergic receptors

Journal of Receptor and Signal Transduction Research

Volumn 17, Issue 4, 1997, Pages 599-607

  Huang, R R C ^a   Rapoport, D ^a   Schaeffer, M T ^a   Cascieri, M A ^a   Fong, T M ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR;

ARTICLE; CHO CELL; DNA SEQUENCE; DOG; GENE ISOLATION; GENOME; MOLECULAR CLONING; NONHUMAN; OPEN READING FRAME; PROTEIN EXPRESSION;

CANIS FAMILIARIS;

EID: 0030808233     PISSN: 10799893     EISSN: None     Source Type: Journal    
DOI: 10.3109/10799899709039152     Document Type: Article

References (12)

1. Dixon, R. A. F.; Kolbilka, B. K.; Strader, D. J.; Benovic, J. L.; Dohlman, H. G.; Frielle, T.; Bolanowski, M. A.; Bennet, C. D.; Rands, E.; Diehl, R. E.; Mumford, R. A.; Slater, E. E.; Sigal, I. S.; Caron, M. G.; Lefkowitz, R. J., and Strader, C. D. Cloning of the gene and cDNA for mammalian b-adrenergic receptor and homology with rhodopsin, Nature 321, 75-79, 1986.
2. Frielle, T.; Collins, S.; Daniel, K. W.; Caron, M. G., and Lefkowitz, R. J. Cloning of the cDNA for the human betal adrenergic receptor, Proc. Nat. Acad. Sci. 84, 7920-7924, 1987.
3. Emorine, L. J.; Marullo, S.; Briend-Sutren, M.-M.; Patey, G.; Tate, K.; Delavier-Klutchko, C., and Strosberg, A. D. Molecular characterization of the human b3-adrenergic receptor, Science 245, 1118-1121, 1989.
4. Frielle, T.; Kolbilka, B.; Lefkowitz, R. J., and Caron, M. G. Human beta1 and beta2 adrenergic receptors: structurally and functionally related receptors derived from distinct genes, Trends Neurosci. 7, 321-324, 1988.
5. Howe, R.; Rao, B. S.; Holloway, B. R., and Stribling, D. Selective beta3 adrenergic agonists of brown adipose tissue and thermogenesis, J. Med. Chem. 35, 1759-1764, 1992.
6. Arch, J. R. S.; Ainsworth, A. T.; Cawthorne, M. A.; Piercy, V.; Sennitt, M. V.; Thody, V. E.; Wilson, C., and Wilson, S. Atypical ß-adrenoceptor on brown adipocyts as target for anti-obesity drugs, Nature 309, 163-165, 1984.
7. Amend, A. M., and Guan, X.-M. Cloning, sequencing and expression of the rhesus monkey beta2 adrenergic receptor, DNA Cell Biol. 14, 753-757, 1995.
8. Cheung, A. H.; Huang, R. R. C., and Strader, C. D. Involvement of specific hydrophobic, but not hydrophilic, amino acids in the third intracellular loop of the bete-adrenergic receptor in the activation of Gs, Mol. Pharmacol. 41, 1061-1065, 1992.
9. Strader, C. D.; Sigal, I. S.; Canderlore, M. R.; Rands, E.; Hill, W. S., and Dixon, R. A. F. Conserved aspartic acid residues 79 and 113 of the beta-adrenergic receptor have different roles in receptor function, J. Biol. Chem. 263, 10267-10271, 1988.
10. Searles, R. P.; Nipper, V. J., and Machida, C. A. The rat beta1 adrenergic receptor gene, DNA Seq. 4, 231-241, 1994.
11. Strader, C. D.; Fong, T. M.; Tota, M. R.; Underwood, D., and Dixon, R. A. F. Structure and function of G protein coupled receptors, Ann. Rev. Biochem. 63, 101-132, 1994.
12. DeBlasi, A.; O'Reilly, K., and Motulsky, H. J. Calculating receptor number from binding experiments using same compound as radioligand and competitor, Trends Pharmacol. Sci. 10, 227-229, 1989.