메뉴 건너뛰기




Volumn 100, Issue 1, 1997, Pages 23-29

Short-term immunotherapy: A prospective, randomized, double-blind, placebo-controlled multicenter study of molecular standardized grass and rye allergens in patients with grass pollen-induced allergic rhinitis

(16)  Zenner, Hans Peter a   Baumgarten, Claus b   Rasp, Gerd c   Fuchs, Thomas d   Kunkel, Gert b   Hauswald, Bettina e   Ring, Johannes f   Effendy, Isaak g   Behrendt, Wolfram h   Frosch, Peter J i   Przybilla, Bernhard c   Brunner, Franz X j   Merk, Hans F k   Kapp, Alexander l   Schnitker, Jörg m   Wolf, Hendrik n  


Author keywords

Allergic rhinitis; Grass pollen; Rye pollen; Short term immunotherapy; Skin prick test; Specific IgE; Specific IgG4; Specific immunotherapy

Indexed keywords

ADOLESCENT; ADULT; ALLERGIC RHINITIS; ARTICLE; CEREAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GRASS POLLEN; HUMAN; IMMUNOTHERAPY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SKIN TEST; TREATMENT OUTCOME;

EID: 0030808143     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(97)70190-8     Document Type: Article
Times cited : (62)

References (24)
  • 1
    • 0026601094 scopus 로고
    • Allergic rhinitis to ragweed pollen. I. Reassessment of the effects of immunotherapy on cellular and humoral responses
    • Brunet C, Bedard PM, Lavoie A, Jobin M, Hebert J. Allergic rhinitis to ragweed pollen. I. Reassessment of the effects of immunotherapy on cellular and humoral responses. J Allergy Clin Immunol 1992;89:87-94.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 87-94
    • Brunet, C.1    Bedard, P.M.2    Lavoie, A.3    Jobin, M.4    Hebert, J.5
  • 3
    • 0024408780 scopus 로고
    • The relationships between late cutaneous responses and specific antibody responses with outcome of immunotherapy for seasonal allergic rhinitis
    • Parker WA, Wishman BA, Apaliski SJ, Reid MJ. The relationships between late cutaneous responses and specific antibody responses with outcome of immunotherapy for seasonal allergic rhinitis. J Allergy Clin Immunol 1989;84:667-77.
    • (1989) J Allergy Clin Immunol , vol.84 , pp. 667-677
    • Parker, W.A.1    Wishman, B.A.2    Apaliski, S.J.3    Reid, M.J.4
  • 4
    • 0025165631 scopus 로고
    • Comparative safety and efficacy of short ragweed extracts differing in potency and composition in the treatment of fall hay fever. Use of allergenically bioequivalent doses by parallel line bioassay to evaluate comparative safety and efficacy
    • Turkeltaub PC, Campbell G, Mosimann JE. Comparative safety and efficacy of short ragweed extracts differing in potency and composition in the treatment of fall hay fever. Use of allergenically bioequivalent doses by parallel line bioassay to evaluate comparative safety and efficacy. Allergy 1990;45:528-46.
    • (1990) Allergy , vol.45 , pp. 528-546
    • Turkeltaub, P.C.1    Campbell, G.2    Mosimann, J.E.3
  • 5
    • 0023774406 scopus 로고
    • Immunotherapy with partially purified and standardized tree pollen extracts. I. Clinical results from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel
    • Nüchel-Petersen B, Janniche H, Munch EP, Wihl JA, Böwadt H, Ipsen H, et al. Immunotherapy with partially purified and standardized tree pollen extracts. I. Clinical results from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel. Allergy 1988;43:353-62.
    • (1988) Allergy , vol.43 , pp. 353-362
    • Nüchel-Petersen, B.1    Janniche, H.2    Munch, E.P.3    Wihl, J.A.4    Böwadt, H.5    Ipsen, H.6
  • 6
    • 0023720329 scopus 로고
    • Prospective study on immunologic changes induced by two different Dermatophagoides pteronyssinus extracts prepared from whole mite culture and mite bodies
    • Wahn U, Schweter C, Lind P, Løwenstein H. Prospective study on immunologic changes induced by two different Dermatophagoides pteronyssinus extracts prepared from whole mite culture and mite bodies. J Allergy Clin Immunol 1988;82:360-70.
    • (1988) J Allergy Clin Immunol , vol.82 , pp. 360-370
    • Wahn, U.1    Schweter, C.2    Lind, P.3    Løwenstein, H.4
  • 8
    • 0023693592 scopus 로고
    • Immunotherapy with partially purified and standardized tree pollen extracts. II. Results of skin prick tests and nasal provocation tests from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel
    • Wihl JA, Ipsen H, Nüchel-Petersen B, Munch EP, Janniche H, Löwenstein H. Immunotherapy with partially purified and standardized tree pollen extracts. II. Results of skin prick tests and nasal provocation tests from a three-year double-blind study of patients treated with pollen extracts either of birch or combinations of alder, birch and hazel. Allergy 1988;43:363-9.
    • (1988) Allergy , vol.43 , pp. 363-369
    • Wihl, J.A.1    Ipsen, H.2    Nüchel-Petersen, B.3    Munch, E.P.4    Janniche, H.5    Löwenstein, H.6
  • 9
    • 0019976416 scopus 로고
    • Immunotherapy with grass pollen major allergens: Clinical results from a prospective 3-year double blind study
    • Österballe O. Immunotherapy with grass pollen major allergens: clinical results from a prospective 3-year double blind study. Allergy 1982;37:379-88.
    • (1982) Allergy , vol.37 , pp. 379-388
    • Österballe, O.1
  • 10
    • 0027467542 scopus 로고
    • A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: Clinical efficacy and side effects
    • Haugaard L, Dahl R, Jacobsen L. A controlled dose-response study of immunotherapy with standardized, partially purified extract of house dust mite: clinical efficacy and side effects. J Allergy Clin Immunol 1993;91:709-22.
    • (1993) J Allergy Clin Immunol , vol.91 , pp. 709-722
    • Haugaard, L.1    Dahl, R.2    Jacobsen, L.3
  • 11
    • 0025979907 scopus 로고
    • Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs
    • Varney VA, Gaga M, Frew AJ, Aber VR, Kay AB, Durham SR. Usefulness of immunotherapy in patients with severe summer hay fever uncontrolled by antiallergic drugs. Br Med J 1991;302:265-9.
    • (1991) Br Med J , vol.302 , pp. 265-269
    • Varney, V.A.1    Gaga, M.2    Frew, A.J.3    Aber, V.R.4    Kay, A.B.5    Durham, S.R.6
  • 12
    • 0002457760 scopus 로고
    • Immunotherapy [position paper]. EAACI Immunotherapy subcommittee
    • Mailing HJ, Weeke B, editors.
    • Mailing HJ, Weeke B, editors. Immunotherapy [position paper]. EAACI Immunotherapy subcommittee. Allergy 1993;48:3-35
    • (1993) Allergy , vol.48 , pp. 3-35
  • 13
    • 0025010886 scopus 로고
    • European Economic Community (EEC) Note for Guidance, Good Clinical Practice for Trials on Medicinal Products in the European Community
    • CPMP Working Party on Efficacy of Medicinal Products. Final Approval 11.7.1990, Date for Coming into Operation 1.7. 1991
    • European Economic Community (EEC) Note for Guidance, Good Clinical Practice for Trials on Medicinal Products in the European Community. CPMP Working Party on Efficacy of Medicinal Products. Final Approval 11.7.1990, Date for Coming into Operation 1.7. 1991, Pharm Toxicol 1990;67:361-72.
    • (1990) Pharm Toxicol , vol.67 , pp. 361-372
  • 14
  • 15
    • 0021932910 scopus 로고
    • The international collaborative study establishing the first international standard for timothy (Phleum pratense) grass pollen allergenic extract
    • Gjesing B, Jaeger L, Marsh DG, Lowenstein H. The international collaborative study establishing the first international standard for timothy (Phleum pratense) grass pollen allergenic extract. J Allergy Clin Immunol 1985;75:258-67.
    • (1985) J Allergy Clin Immunol , vol.75 , pp. 258-267
    • Gjesing, B.1    Jaeger, L.2    Marsh, D.G.3    Lowenstein, H.4
  • 16
    • 0022651777 scopus 로고
    • Immunotherapy with partially purified and standardized animal dander extracts. I. Clinical results from a double-blind study on patients with animal dander asthma
    • Sundin B, Lilja G, Graff-Lonnevig V, Hedlin G, Heilborn H, Norrlind K, et al. Immunotherapy with partially purified and standardized animal dander extracts. I. Clinical results from a double-blind study on patients with animal dander asthma. J Allergy Clin Immunol 1986;77:478-87.
    • (1986) J Allergy Clin Immunol , vol.77 , pp. 478-487
    • Sundin, B.1    Lilja, G.2    Graff-Lonnevig, V.3    Hedlin, G.4    Heilborn, H.5    Norrlind, K.6
  • 17
    • 0018166759 scopus 로고
    • Standardization of allergen extracts with appropriate methods. the combined use of skin prick testing and radio-allergosorbent tests
    • Aas K, Backmann A, Belin L, Weeke B. Standardization of allergen extracts with appropriate methods. The combined use of skin prick testing and radio-allergosorbent tests. Allergy 1978;33:130-7.
    • (1978) Allergy , vol.33 , pp. 130-137
    • Aas, K.1    Backmann, A.2    Belin, L.3    Weeke, B.4
  • 18
    • 0021666221 scopus 로고
    • Procedures for comparing samples with multiple endpoints
    • O'Brien PC. Procedures for comparing samples with multiple endpoints. Biometrics 1984;40:1079-87.
    • (1984) Biometrics , vol.40 , pp. 1079-1087
    • O'Brien, P.C.1
  • 19
    • 0025882782 scopus 로고
    • Procedures for two-sample comparisons with multiple endpoints controlling the experimentwise error rate
    • Lehmacher W, Wassmer G, Reitmeir P. Procedures for two-sample comparisons with multiple endpoints controlling the experimentwise error rate. Biometrics 1991;47:511-21.
    • (1991) Biometrics , vol.47 , pp. 511-521
    • Lehmacher, W.1    Wassmer, G.2    Reitmeir, P.3
  • 20
    • 0025183661 scopus 로고
    • Comparison of the in-vivo and in-vitro response to ragweed immunotherapy in children and adults with ragweed-induced rhinitis
    • Hedlin G, Silber G, Naclerio R, Proud D, Lamas AM, Eggleston P, et al. Comparison of the in-vivo and in-vitro response to ragweed immunotherapy in children and adults with ragweed-induced rhinitis. Clin Exp Allergy 1990;20:491-500.
    • (1990) Clin Exp Allergy , vol.20 , pp. 491-500
    • Hedlin, G.1    Silber, G.2    Naclerio, R.3    Proud, D.4    Lamas, A.M.5    Eggleston, P.6
  • 21
    • 0025047538 scopus 로고
    • A placebo-controlled trial of immunotherapy with two extracts of Dermatophagoides pteronyssinus in allergic rhinitis, comparing clinical outcome with changes in antigen-specific IgE, IgG, and IgG subclasses
    • McHugh SM, Lavelle B, Kemeny DM, Patel S, Ewan PW. A placebo-controlled trial of immunotherapy with two extracts of Dermatophagoides pteronyssinus in allergic rhinitis, comparing clinical outcome with changes in antigen-specific IgE, IgG, and IgG subclasses. J Allergy Clin Immunol 1990;86:521-32.
    • (1990) J Allergy Clin Immunol , vol.86 , pp. 521-532
    • McHugh, S.M.1    Lavelle, B.2    Kemeny, D.M.3    Patel, S.4    Ewan, P.W.5
  • 22
    • 0022411593 scopus 로고
    • The subclass nature and clinical significance of the IgG antibody response in patients undergoing allergen-specific immunotherapy
    • Djurup R. The subclass nature and clinical significance of the IgG antibody response in patients undergoing allergen-specific immunotherapy. Allergy 1985;40:469-86.
    • (1985) Allergy , vol.40 , pp. 469-486
    • Djurup, R.1
  • 23
    • 0025910635 scopus 로고
    • The role of IgG subclass antibodies in the clinical response to immunotherapy in allergic disease
    • Nakagawa T. The role of IgG subclass antibodies in the clinical response to immunotherapy in allergic disease. Clin Exp Allergy 1991;21:289-96.
    • (1991) Clin Exp Allergy , vol.21 , pp. 289-296
    • Nakagawa, T.1
  • 24
    • 0025179309 scopus 로고
    • Evaluation of immunotherapy-induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting: Correlation with clinical response
    • Birkner T, Rumpold H, Jarolin E, Ebner H, Breitenbach M, Skvaril F, et al. Evaluation of immunotherapy-induced changes in specific IgE, IgG and IgG subclasses in birch pollen allergic patients by means of immunoblotting: correlation with clinical response. Allergy 1990;45:418-26.
    • (1990) Allergy , vol.45 , pp. 418-426
    • Birkner, T.1    Rumpold, H.2    Jarolin, E.3    Ebner, H.4    Breitenbach, M.5    Skvaril, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.