Yeast hexokinase inhibitors designed from the 3-D enzyme structure rebuilding

Journal of Enzyme Inhibition

Volumn 12, Issue 2, 1997, Pages 101-121

  Willson, Michele ^a   Alric, Isabelle ^a   Perie, Jacques ^a   Sanejouand, Yves Henri ^b  

^a Université Paul Sabatier   (France)

^b CNRS   (France)

Author keywords

Enzyme structure rebuilding; Hexokinase; Inhibitors; Kinetics; NMR spectroscopy

Indexed keywords

ENZYME INHIBITOR; HEXOKINASE;

ARTICLE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; YEAST;

EID: 0030806989     PISSN: 87555093     EISSN: None     Source Type: Journal    
DOI: 10.3109/14756369709035812     Document Type: Article

References (34)

1. Willson, M., Callens, M., Kuntz, D.A., Périé, J. and Opperdoes, F.R. (1993) Mol. Biochem. Parasitol., 59, 201-210.
2. Willson, M., Lauth, N., Périé, J., Callens, M. and Opperdoes, F.R. (1994) Biochemistry, 33, 214-220.
3. Potsma, P.W. and Lengerler, J.W. (1985) Microbiol. Rev., 49, 232-239.
4. Bisson, L.F. and Fraenkel, D.F. (1983) Proc. Natl. Acad. Sci. USA, 80, 1730-1734.
5. Visser, N. and Opperdoes, F.R. (1980) Eur. J. Biochem., 103, 623-632.
6. Périé, J., Alric, I., Blonski, C., Gefflaut, T., Lauth de Viguerie, N., Trinquier, M., Willson, M., Callens, M. and Opperdoes, F.R. (1994) Pharmac. Ther., 60, 347-365.
7. Swarup, G. and Kenkare, U.W. (1980) Biochemistry, 19, 4058-4064.
8. Schirch, D.M. and Wilson, J.E. (1987) Arch. Biochem. Biophys., 254, 385-396.
9. Magnani, M., Stocchi, V., Serafini, G. and Chiarantini, L. (1988) Biochem. Biophys. Acta, 954, 336-343.
10. Mehta, A.M., Jarori, G.K. and Kenkare, U.W. (1988) Biol. Chem., 263, 15492-15498.
11. Akerfeldt, K.S. and Bartlett, P.A. (1991) J. Org. Chem., 56, 7133-7144.
12. Alric, I., Willson, M. and Périé, J. (1991) Phosphorus and Sulfur, 56, 71-80.
13. Bennett, W.S. and Steitz, T.A. (1980) J. Mol. Biol., 140, 183-209.
14. Bennett, W.S. and Steitz, T.A. (1980) J. Mol. Biol., 140, 211-230.
15. Steitz, T.A., Fletteik, R.J., Anderson, W.F. and Anderson, C.M. (1976) J. Mol. Biol., 104, 197-222.
16. Anderson, C.M., Sienkamp, R.E., McDonald, R.C. and Steitz, T.A. (1978) J. Mol. Biol., 123, 207-219.
17. Maley, F. and Lardy, H.A. (1955) J. Biol. Chem., 214, 765-773.
18. Perie, J., Alric, I., Blonski, C., Chauviére, G., Lauth, N., Willson, M., Albuquerque, C., Gefflaut, T. and Trinquier, M. (1993) Actual. Chim. Ther., 20, 111-148.
19. Steitz, T.A., Anderson, W.F., Fletterick, R.J. and Anderson, C.M. (1977) J. Biol. Chem., 252, 4494-4500.
20. Stachelek, C., Stachelek, J., Swan, J., Boistein, D. and Konisgberg, W. (1986) Nucleic Acid Res., 14, 945-963.
21. Fothergill-Gilmore, L. and Michels, P.A.M. (1993) Prog. Biophys. Mol. Biol., 2, 105-177.
22. Coats, E.A., Skau, K.A., Caperelli, C.A. and Solamacha, D. (1993) J. Enz. Inhibit., 6, 271-282.
23. Alric, I. (1991) Thesis, no. 1026, Paul Sabatier University, Toulouse France.
24. Rose, I.A. (1995) Meth. Enzymol., 249, 315-340.
25. Kaji, A., Trayser, K.A. and Colowick, S.P. (1961) Fed. Proc., 20, 233-239.
26. Zewe, V., Fromm, M. and Fabiano, R. (1964) J. Biol. Chem., 239, 1625-1634.
27. Tebby, J.C. and Glonek, T. (1991) Handbook of Phosphorus-31 NMR Data (J. Tebby (ed.)). CRC press; Boca Raton, Fl.
28. Baijal, M. and Wilson, J.E. (1992) Arch. Biochem. Biophys., 298, 271-278.
29. Sols, A., De La Fuente, G., Villar-Palasi, C. and Asensio, C. (1958) Biochem. Biophys. Acta, 30, 92-101.
30. De la Fuente, G., Lagunas, R. and Sols, A. (1970) Eur. J. Biochem., 16, 226-233.
31. Menezez, L.C. and Pudles, J. (1977) Arch. Biochem. Biophys., 178, 34-42.
32. Trinquier-Dinet, M. (1995) Thesis, no. 126, Paul Sabatier University, Toulouse France.
33. Lipmar, D.J. and Pearson, W.R. (1985) Science, 227, 1435-1446.
34. Krauslis, P.J. (1991) J. Appl. Crystallogr., 24, 946-952.