Expression of CD44 standard form and variant isoforms in non-small cell lung carcinomas

Human Pathology

Volumn 28, Issue 7, 1997, Pages 809-814

  Tran, T Anh ^a   Kallakury, Bhaskar V S ^a   Sheehan, Christine E ^a   Ross, Jeffrey S ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

Author keywords

CD44s; CD44v; Immunohistochemistry; Non small cell lung carcinoma

Indexed keywords

CELL ADHESION MOLECULE; HERMES ANTIGEN; MONOCLONAL ANTIBODY;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER RECURRENCE; CANCER STAGING; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG ALVEOLUS CELL; LUNG NON SMALL CELL CANCER; LUNG SQUAMOUS CELL CARCINOMA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PROGNOSIS; SURVIVAL RATE; TUMOR DIFFERENTIATION;

EID: 0030806945     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(97)90154-4     Document Type: Article

References (36)

1. Aruffo A, Stamenkovic I, Melnick M, et al: CD44 is the principal cell surface receptor for hyaluronate. Cell 61:1303-1313, 1990
2. Jalkanen ST, Bargatze RF, Herron LR, et al: A lymphoid cell-surface glycoprotein involved in endothelial-cell recognition and lymphocyte homing in man. Eur J Immunol 16:1195-1202, 1986
3. Kansas GS, Wood GS, Daily MO: A family of cell-surface glycoproteins defined by a putative anti-endothelial cell receptor antibody in man. J Immunol 142:3050-3057, 1989
4. Picker LJ, Nakache M, Butcher EC: Monoclonal antibodies to human lymphocyte homing receptors define a novel class of adhesion molecules on diverse types. J Cell Biol 109:927-937, 1989
5. St John T, Meyer J, Idzera R, et al: Expression of CD44 confers a new adhesive phenotype on transfected cells. Cell 60:45-52, 1990
6. Carter WG, Wayner EA: Characterization of a collagen-binding phosphorylated transmembrane glycoprotein expressed in nucleated human cells. J Biol Chem 263:4193-4201, 1988
7. Stamenkovic I, Amiot M, Pesando LM, et al: A lymphocyte molecule implicated in lymph node homing is a member of the cartilage link protein family. Cell 56:1057-1062, 1989
8. Brown TA, Bouchard T, St John T, et al: Human keratinocytes express a new CD44 core protein (CD44E) as a heparin-sulfate intrinsic membranes proteoglycan with additional exons. J Cell Biol 113:207-221, 1991
9. Haynes BF, Telen MJ, Hale LP, et al: CD44: A molecule involved in leukocyte adherence and T-cell activation. Immunol Today 10:424-428, 1989
10. Screaton GR, Bell MV, Jackson DG, et al: Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci USA 89:12160-12164, 1992
11. Shtivelman E, Bishop JM: Expression of CD44 is repressed in neuroblastoma cells. Mol Cell Biol 11:5446-5453, 1991
12. Screaton GR, Bell MV, Bell JI, et al: The identification of a new alternative exon with highly restricted tissue expression in transcripts encoding the mouse Pgp-1 (CD44) homing receptor: Comparison of all 10 variant exons between mouse, human, and rat. J Biol Chem 268:12235-12238, 1993
13. Tolg C, Hofmann M, Herrlich P, et al: Splicing choice from ten variant exons establishes CD44 variability. Nucl Acids Res 21:1225-1229, 1993
14. Jackson DG, BuckleyJ, Bell JI: Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain. J Biol Chem 267:4732-4739, 1992
15. Goldstein LA, Zhou DF, Picker LJ, et al: A human lymphocyte homing receptor, the heme antigen, is related to cartilage proteoglycan core and link proteins. Cell 56:1063-1072, 1989
16. Jakanen S, Joensuu H, Soderstrom FO, et al: Lymphocyte homing and clinical behavior of non-Hodgkin lymphoma. J Clin Invest 87:1835-1840, 1991
17. Joensuu H, Klemi PJ, Toikkanen S, et al: Glycoproteins CD44 expression and its association with survival in breast cancer. Am J Pathol 143:867-874, 1993
18. Moshaluk CA, Hamilton SR: Expression of CD44 in Barretts esophagus and associated neoplasms. Mod Pathol 7:65A, 1994
19. Fujita N, Yaegashi N, Ide Y, et al: Expression of CD44 in normal human versus tumor endometrial tissues: Possible implication of reduced expression of CD44 in lymph-vascular space. Cancer Res 54:3922-3928, 1994
20. del Rosario AD, Bui HX, Wu AS, et al: CD44 and E-cadherin expression in transitional cell carcinoma of the urinary bladder. Mod Pathol 7:73A, 1994
21. Kallakury BVS, Yang F, Figge J, et al: Decreased levels of CD44 protein and mRNA in prostate cancer: Correlation with tumor grade and ploidy. Mod Pathol 7:75A, 1996
22. Gunthert U, Hofmann M: A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells. Cell 65:13-24, 1991
23. Harn HJ, Ho LI, Chang JY, et al: Differential expression of the human metastasis adhesion molecule CD44v in normal and carcinomatous stomach mucosa of Chinese subjects. Cancer 75:1065-1071, 1994
24. Heider KH, Dammrich J, Skroch-Angel P, et al: Differential expression of CD44 splice variants in intestinal and diffuse human gastric carcinomas and normal gastric mucosa. Cancer Res 53:4197-4203, 1993
25. Mulder JWR, Kruyt PM, Sewnath M, et al: Colorectal cancer prognosis and expression of exon v6 containing CD44 proteins. Lancet 344:1470-1472, 1994
26. Takenchi K, Yamaguchi A, Urano T, et al: Expression of CD44 variant exons 8-10 in colorectal cancer and its relationship to metastasis. Jpn J Cancer Res 86:292-297, 1995
27. Dall P, Heider KH, Sinn HP, et al: Comparison of immunohistochemistry and RT-PCR for detection of CD44v expression, a new prognostic factor in human breast cancer. Int J Cancer 60:471-477, 1995
28. Kaufmann M, Heider KH, Sinn HP, et al: CD44 variant exon epitopes in primary breast cancer and length of survival. Lancet 345:615-619, 1995
29. Kainz CH, Kohlberger P, Slintz G, et al: Splice variants of CD44 in human cervical cancer stage IB to IIB. Gynecol Oncol 54:383-387, 1995
30. Penno MB, August JT, Baylin SB, et al: Expression of CD44 in human lung tumors. Cancer Res 54:1381-1387, 1994
31. Jackson DG, Schenker T, Weibel R, et al: Expression of alter-natively spliced forms of the CD44 extracellular-matrix receptor on human lung carcinomas. Int J Cancer Suppl 8:110-115, 1994
32. Washimi O, Ueda R, Ariyoshi Y, et al: Expression of CD44 variant isoforms in normal and neoplastic cells of the lung. Jpn J Cancer Res 85:1112-1116, 1994
33. Telen MJ, Eisenbarth GS, Haynes BF: Human erythrocyte antigen: Regulation of expression of a novel erythrocyte surface antigen by the inhibitor Lutheran [N(Lu)] gene. J Clin Invest 71:1878-1886, 1983
34. Shi SR, Key ME, Kalra KL: Antigen retrieval in formalinfixed, paraffin-embedded tissues: An enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. J Histochem Cytochem 39:741-748, 1991
35. Auerbach: Natural history of carcinoma of the lung, in Fisherman AP (ed): Pulmonary Diseases and Disorders. New York, NY, Mc Graw-Hill, 1980, pp 1388-1396
36. Mackay CR, Terpe HJ, Stander R, et al: Expression and modulation of CD44 variant isoforms in humans. J Cell Biol 124:71-82, 1994