Allogeneic bone marrow transplantation with matched unrelated donors for patients with hematologic malignancies using a preparative regimen of high-dose cyclophosphamide and fractionated total body irradiation

Bone Marrow Transplantation

Volumn 20, Issue 3, 1997, Pages 219-225

  Geller, R B ^a,b   Devine, S M ^a   O'Toole, K ^a   Persons, L ^a   Keller, J ^a   Mauer, D ^a   Holland, H K ^a   Dix, S P ^a   Piotti, M ^a   Redei, I ^a   Connaghan, G ^a   Heffner, L T ^a   Hillyer, C D ^a   Waller, E K ^a   Winton, E F ^a   Wingard, J R ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST LUKE S HOSPITAL   (United States)

Author keywords

Bone marrow transplant; CY TBI; Hematologic malignancies; Preparative regimen; Unrelated donors

Indexed keywords

CREATININE; CYCLOPHOSPHAMIDE; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; TACROLIMUS;

ADULT; ALLOGENIC BONE MARROW TRANSPLANTATION; ARTICLE; BONE MARROW DEPRESSION; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONDITIONING; CREATININE BLOOD LEVEL; DONOR; DRUG MEGADOSE; GRAFT FAILURE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HLA MATCHING; HUMAN; LIVER VEIN OBSTRUCTION; MYELOPROLIFERATIVE DISORDER; NEPHROTOXICITY; PRIORITY JOURNAL; PROGNOSIS; RELAPSE; REMISSION; WHOLE BODY RADIATION;

EID: 0030806784     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1700874     Document Type: Article

References (25)

1. Geller RB, Saral R, Piantadosi S et al. Allogeneic bone marrow transplantation after high dose busulfan and cyclophosphamide in patients with acute nonlymphocytic leukemia. Blood 1989; 73: 2209-2218.
2. Copelan EA, Biggs JC, Thompson JM et al. Treatment for acute myelocytic leukemia with allogeneic bone marrow transplantation following preparation with Bu/Cy 2. Blood 1991; 78: 838-843.
3. Clift RA, Buckner CD, Appelbaum FR et al. Allogeneic marrow transplantation in patients with chronic myeloid leukemia in the chronic phase: a randomized trial of two irradiation regimens. Blood 1991; 77: 1660-1665.
4. Buckner CD, Clift RA, Appelbaum FR et al. A randomized study comparing two transplant regimens for CML in chronic phase. Blood 1992; 80: 72a.
5. Gahrton G, Tura S, Ljungman P et al. Allogeneic bone marrow transplantation in multiple myeloma. New Engl J Med 1991; 325: 1267-1273.
6. Copelan EA, Kapoor N, Gibbins B et al. Allogeneic marrow transplantation in non-Hodgkin's lymphoma. Bone Marrow Transplant 1990; 5: 47-50.
7. Storb R, Deeg HJ, Farewell K et al. Marrow transplantation for severe aplastic anemia: methotrexate alone compared with a combination of methotrexate and cyclosporine for prevention of graft-vs-host disease. Blood 1986; 68: 119-125.
8. Gluckman E, Devergie A, Meletis J et al. Bone marrow transplantation in severe aplastic anemia. Report of 97 consecutive patients. Bone Marrow Transplant 1987; 2: 101-107.
9. O'Reilly RJ, Dupont B, Pahwa S et al. Reconstitution in severe combined immunodeficiency by transplantation of marrow from an unrelated donor. New Engl J Med 1977; 297: 1311-1318.
10. Gordon-Smith EC, Fairhead SM, Chipping PM et al. Bone marrow transplantation for severe aplastic anemia using histocompatible unrelated volunteer donors. Br Med J 1982; 285: 835-837.
11. Kernan NA, Bartsch G, Ash RC et al. Analysis of 462 transplantations from unrelated donors facilitated by the National Marrow Donor Program. New Engl J Med 1993; 328: 593-602.
12. McGlave P, Bartsch G, Anasetti C et al. Unrelated donor marrow transplantation therapy for CML. Initial experience of the NMDP. Blood 1993; 81: 543-551.
13. Beatty PG, Dahlberg S, Mickelson EM et al. Probability of finding HLA matched unrelated marrow donors. Transplantation 1988; 45: 714-718.
14. Clift RA, Buckner CD, Thomas ED et al. The treatment of acute non-lymphoblastic leukemia by allogeneic marrow transplantation. Bone Marrow Transplant 1987; 2: 243-258.
15. Wingard JR, Piantadosi S, Santos GW et al. Allogeneic bone marrow transplantation for patients with high risk acute lymphoblastic leukemia. J Clin Oncol 1990; 8: 820-830.
16. Goodrich JM, Mori M, Gleaves C et al. Early treatment with ganciclovir to prevent cytomegalovirus disease after allogeneic bone marrow transplantation. New Engl J Med 1991: 325: 1601-1607.
17. Devine SM, Geller RB, Lin LB et al. The outcome of unrelated donor bone marrow transplantation in patients with hematologic malignancies using tacrolimus (FK506) and low dose methotrexate for graft-versus-host prophylaxis. Biol Blood Marrow Transplant (in press).
18. Green S, Weiss G. Southwest Oncology Group standard response criteria, endpoint definitions, and toxicity criteria. Invest New Drugs 1992; 10: 239-253.
19. Thomas ED, Storb R, Clift RA et al. Bone marrow transplantation. New Engl J Med 1975; 292: 832-836.
20. McDonald GB, Hinds MS, Fisher LD et al. Venocclusive disease of the liver and multiorgan failure following marrow transplantation: a cohort study of 355 patients. Ann Intern Med 1993; 118: 225-267.
21. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1985; 53: 457-461.
22. Ash RC, Casper JT, Chitambar CR et al. Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors. New Engl J Med 1990; 322: 485-494.
23. Clift RA, Buckner CD, Appelbaum FR et al. Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission. A randomized trial of two irradiation regimens. Blood 1990; 76: 1867-1871.
24. Bearman SI, Mori M, Beatty PG et al. Comparison of morbidity and mortality after marrow transplantation from HLA-genotypically identical siblings and HLA-phenotypically identical unrelated donors. Bone Marrow Transplant 1994; 13: 31-35.
25. Miralbell R, Bieri S, Mermillod B et al. Renal toxicity after allogeneic bone marrow transplantation: the combined effects of total-body irradiation and graft-versus-host disease. J Clin Oncol 1996; 14: 579-585.