Effects of vanadyl sulphate on glucose homeostasis in severe diabetes induced by streptozotocin in rats

Indian Journal of Medical Research

Volumn 106, Issue NOV., 1997, Pages 481-485

  Dehghani, G A ^a   Ahmadi, S ^a   Omrani, G R ^a  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Antidiabetic action; Insulin sensitivity; Vanadyl

Indexed keywords

ANTIDIABETIC AGENT; GLUCOSE; INSULIN; ISOPHANE INSULIN; STREPTOZOCIN; VANADYL SULFATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FLUID INTAKE; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; STREPTOZOCIN DIABETES;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DRINKING; HOMEOSTASIS; HYPOGLYCEMIC AGENTS; INSULIN; MALE; RATS; STREPTOZOCIN; VANADIUM COMPOUNDS; WEIGHT LOSS;

EID: 0030806628     PISSN: 09715916     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Becker DJ, Ongemba LN, Henquin JC. Comparison of the effects of various vanadium salts on glucose homeostasis in streptozotocin-diabetic rats. Eur J Pharmacol 1994 : 260 : 169-75.
2. Malabu UH, Dryden S, McCarthy HD, Kilpatric KA, Williams G. Effects of chronic vanadate administration in the STZ-induced diabetic rat. Diabetes 1994; 43 : 9-15.
3. Pederson RA, Ramanadham S, Buchan AMJ, McNeill JH. Long-term effects of vanadyl treatment on streptozocin-induced diabetes in rats. Diabetes 1989; 38 : 1390-5.
4. Heyliger CE, Tahiliani AG, McNeill JH. Effect of vanadate on elevated blood glucose and depressed cardiac performance of diabetic rats. Science 1985; 227 : 1474-7.
5. Duckworth WC, Solomon SS, Liepnieks J, Hamel FG, Hand S, Peavy DE. Insulin-like effects of vanadate in isolated rat adipocytes. Endocrinology 1988; 122 : 2285-9.
6. Venkatesan N, Avidan A, Davidson MB. Antidiabetic action of vanadyl in rats independent of in vivo insulin-receptor kinase activity. Diabetes 1991; 40 : 492-8.
7. Pugazhenthi S, Khandelwal RL. Insulin-like effects of vanadate on hepatic glycogen metabolism in nondiabetic and streptozocin-induced diabetic rats. Diabetes 1990; 39 : 821-7.
8. Dehghani GA, Atapour N, Sotoodeh M, Omrani GR. The influences of vanadyl sulphate on islet cells, blood glucose, and insulin levels of normal and STZ-induced diabetic rats. Iranian J Med Sci 1992; 13 : 167-73.
9. Dehghani GA, Atapour N, Sotoodeh M, Omrani GR. Trophic effects of vanadyl sulphate on pancreatic beta cells of chronic partially streptozotocin-induced diabetic rats. Iranian J Med Sci 1994; 19(1&2): 22-7.
10. Cam MC, Pederson RA, Brownsey RW, McNeill JH. Long-term effectiveness of oral vanadyl sulphate in streptozotocin diabetic rats. Diabetologia 1993; 36 : 218-24.
11. Cam MC, Faun, J, McNeill JH. Concentration-dependent glucose-lowering effects of oral vanadyl are maintained following treatment withdrawl in streptozotocin-diabetic rats. Metabolism 1995; 44 : 332-9.
12. Yuen VG, Orving C, McNeill JH. Glucose lowering effects of a new complex, bis(maltolato) oxovanadium (IV). Can J Physiol Pharmacol 1993; 71 : 263-9.