9-Hydroxycrisamicin A, a new cytotoxic isochromanquinone antibiotic produced by Micromonospora sp. SA246

Journal of Antibiotics

Volumn 50, Issue 7, 1997, Pages 546-550

  Yeo, Woon Hyung ^a   Yun, Bong Sik ^b   Back, Nam In ^c   Kim, Young Ho ^a   Kim, Sang Seock ^a   Park, Eun Kyung ^a   Whang, Kyung Sook ^d   Yu, Seung Hun ^e  

^a Korea Ginseng Corporation   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Kyung Hee University   (South Korea)

^d Mokwon University   (South Korea)

^e Chungnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

9 HYDROXYCRISAMICIN A; ANTINEOPLASTIC ANTIBIOTIC; CYTOTOXIC AGENT; UNCLASSIFIED DRUG;

ANTIBIOTIC BIOSYNTHESIS; ANTIMICROBIAL ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CENTRAL NERVOUS SYSTEM TUMOR; COLON CANCER; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; FAST ATOM BOMBARDMENT MASS SPECTROMETRY; FERMENTATION; GRAM POSITIVE BACTERIUM; HUMAN; HUMAN CELL; LUNG CANCER; MELANOMA; MICROMONOSPORA; MINIMUM INHIBITORY CONCENTRATION; OVARY CANCER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TAXONOMY;

EID: 0030806549     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.50.546     Document Type: Article

References (10)

1. NELSON, R. A.; J. A. POPE, Jr., G. M. LUEDEMANN, L. E. MCDANIEL & C. P. SCHAFFNER: Crisamicin A, a new antibiotic from Micromonospora. I. Taxonomy of the producing strain, fermentation, isolation, physicochemical characterization and antimicrobial properties. J. Antibiotics 39: 335-344, 1986
2. LING, D.; L. S. SHIELD & K. L. RINEHART, Jr.: Isolation and structure determination of crisamicin A, a new antibiotic from Micromonospora purpureochromogenes subsp. halotolerans. J. Antibiotics 39: 345-353, 1986
3. NELSON, R. A.; J. A. POPE, Jr., R. C. PANDEY, L. E. MCDANIEL, C. P. SCHAFFNER, R. L. BEVERIDGE, P. H. HOOPS & F. JORDAN: Studies on the biosynthesis of the antibiotic crisamicin A and carbon-13 magnetic resonance assignments. J. Antibiotics 41: 1659-1667, 1988
4. RUSSELL, W. L.; R. C. PANDEY & C. P. SCHAFFNER: Crisamicin C, a new isochromanquinone antibiotic. Isolation, structure determination, and biosynthesis. J. Antibiotics 41: 149-156, 1988
5. WILLIAMS, S. T.; M. GOODFELLOW, G. ALDERSON, E. M. H. WELLINGTON, P. H. A. SNEATH & M. J. SACKIN: Numerical classification of Streptomyces and related genera. J. General Microbiol. 129: 1743-1813, 1983
6. SHIRLING, E. B. & D. GOTTLIEB: Methods for characterization of Streptomyces species. Int. J. Syst. Bacteriol. 16: 313-340, 1966
7. SCHAAL, K., P.: In Chemical Methods in Bacterial Systematics. Eds., GOODFELLOW and MINNIKIN, pp. 359-381, Academic Press, 1985
8. DIETZ, A. & J. MATHEWS: Classification of Streptomyces spore surface into five groups. Appl. Microbiol. 21: 527-533, 1971
9. SKEHAN, P. R.; STORENG, D. SCUDIERO, A. MONKS, J. MCMAHON, D. VISTICA, J. T. WARREN, H. BOKESCH, S. KENNY & M. R. BOYD: New calorimetric cytotoxicity assay for anticancer-drug screening. J. NCI. 82: 1107-1112, 1990
10. WILLIAMS, S. T.; M. GOODFELLOW & G. ALDERSON: In BERGEY'S Manual of Systematic Bacteriology. Volume 4. Eds., S. T. WILLIAMS et al., pp. 2348-2492, Williams & Wilkins Co., 1989