Hypoxia inhibits nitric oxide synthesis in isolated rabbit lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 272, Issue 6 16-6, 1997, Pages

  Kantrow, Stephen P ^a   Huang, Yuh Chin T ^a   Whorton, A Richard ^a   Grayck, Eva N ^a   Knight, Jennifer M ^a   Millington, David S ^a   Piantadosi, Claude A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Hypoxic pulmonary vasoconstriction; Oxygen

Indexed keywords

N(G) METHYLARGININE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; OXYGEN; S NITROSOGLUTATHIONE; VANADIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANOXIA; ARTICLE; CONTROLLED STUDY; HYPOXIA; LUNG; LUNG VASOCONSTRICTION; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SYNTHESIS;

EID: 0030806363     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1997.272.6.l1167     Document Type: Article

References (32)

1. 2 sensor in rat pulmonary vasculature. Circ. Res. 73: 1100-1112, 1993.
2. Braman, R. S., and S. A. Hendrix. Nanogram nitrite and nitrate determination in environmental and biological materials by vanadium (III) reduction with chemiluminescence detection. Anal. Chem. 61: 2715-2718, 1989.
3. 2+-dependent nitric oxide synthase in bovine aortic endothelial cells. Am. J. Physiol. 269 (Cell Physiol. 38): C757-C765, 1995.
4. Campos, K. L., J. Giovanelli, and S. Kaufman. Characteristics of the nitric oxide synthase-catalyzed conversion of arginine to N-hydroxyarginine, the first oxygenation step in the enzymic synthesis of nitric oxide. J. Biol. Chem. 270: 1721-1728, 1995.
5. 2 sensor protein in the rat carotid body. Biochem. J. 272: 743-747, 1990.
6. Fishman, A. P. Hypoxia on the pulmonary circulation. How and where it acts. Circ. Res. 38: 221-231, 1976.
7. Greene, B., A. J. Pacitti, and W. W. Souba. Characterization of L-arginine transport by pulmonary artery endothelial cells. Am. J. Physiol. 264 (Lung Cell. Mol. Physiol. 8): L351-L356, 1993.
8. Grimminger, F., R. Spriestersbach, N. Weissmann, D. Walmrath, and W. Seeger. Nitric oxide generation and hypoxic vasoconstriction in buffer-perfused rabbit lungs. J. Appl. Physiol. 78: 1509-1515, 1995.
9. Grimminger, F., N. Weissmann, R. Spriestersbach, E. Becker, S. Rosseau, and W. Seeger. Effects of NADPH oxidase inhibitors on hypoxic vasoconstriction in buffer-perfused rabbit lungs. Am. J. Physiol. 268 (Lung Cell. Mol. Physiol. 12): L747-L752, 1995.
10. Hampl, V., D. N. Cornfield, N. J. Cowan, and S. L. Archer. Hypoxia potentiates nitric oxide synthesis and transiently increases cytosolic calcium levels in pulmonary artery endothelial cells. Eur. Respir. J. 8: 515-522, 1995.
11. Hey, C., I. Wessler, and K. Racke. Nitric oxide synthase activity is inducible in rat, but not rabbit alveolar macrophages, with a concomitant reduction in arginase activity. Naunyn Schmiedebergs Arch. Pharmacol. 351: 651-659, 1995.
12. Huang, Y. C., E. S. Nozik, and C. A. Piantadosi. Superoxide dismutase potentiates platelet-activating factor-induced injury in perfused lung. Am. J. Physiol. 266 (Lung Cell. Mol. Physiol. 10): L246-L254, 1994.
13. Ischiropoulos, H., L. Zhu, and J. S. Beckman. Peroxynitrite formation from macrophage-derived nitric oxide. Arch. Biochem. Biophys. 298: 446-451, 1992.
14. Kim, Y. M., and J. R. Lancaster. Tetrahydrobiopterin-dependent nitrite oxidation to nitrate in isolated rat hepatocytes. FEBS Lett. 332: 255-259, 1993.
15. Kozlowski, R. Z. Ion channels, oxygen sensation and signal transduction in pulmonary arterial smooth muscle. Cardiovasc. Res. 30: 318-325, 1995.
16. Malinski, T., Z. Taha, S. Grunfeld, S. Patton, M. Kapturczak, and P. Tomboulian. Diffusion of nitric oxide in the aorta wall monitored in situ by porphyrinic microsensors. Biochem. Biophys. Res. Commun. 193: 1076-1082, 1993.
17. Marshall, B. E., C. Marshall, F. Frasch, and C. W. Hanson. Role of hypoxic pulmonary vasoconstriction in pulmonary gas exchange and blood flow distribution. I. Physiologic concepts. Intensive Care Med. 20: 291-297, 1994.
18. Marshall, C., and B. Marshall. Site and sensitivity for stimulation of hypoxic pulmonary vasoconstriction. J. Appl. Physiol. 55: 711-716, 1983.
19. McQuillan, L. P., G. K. Leung, P. A. Marsden, S. K. Kostyk, and S. Kourembanas. Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H1921-H1927, 1994.
20. Millington, D. S., D. H. Chace, S. L. Hillman, N. Kodo, and N. Terada. Diagnosis of metabolic disease. In: Biological Mass Spectrometry: Present and Future, edited by T. Matsuo, R. M. Caprioli, M. L. Gross, and Y. Seyama. New York: Wiley, 1994, p. 559-579.
21. Rengasamy, A., and R. A. Johns. Characterization of endothelium-derived relaxing factor/nitric oxide synthase from bovine cerebellum and mechanism of modulation by high and low oxygen tensions. J. Pharmacol. Exp. Ther. 259: 310-316, 1991.
22. m for oxygen of nitric oxide synthase isoforms. J. Pharmacol. Exp. Ther. 276: 30-33, 1996.
23. Schoedon, G., N. Blau, M. Schneemann, G. Flury, and A. Schaffner. Nitric oxide production depends on preceding tetrahydrobiopterin synthesis by endothelial cells: selective suppression of induced nitric oxide production by sepiapterin reductase inhibitors. Biochem. Biophys. Res. Commun. 199: 504-510, 1994.
24. Shaul, P. W., and L. B. Wells. Oxygen modulates nitric oxide production selectively in fetal pulmonary endothelial cells. Am. J. Respir. Cell Mol. Biol. 11: 432-438, 1994.
25. Singh, R. J., N. Hogg, J. Joseph, and B. Kalyanaraman. Mechanism of nitric oxide release from S-nitrosothiols. J. Biol. Chem. 271: 18596-18603, 1996.
26. Stamler, J. S., D. J. Singel, and J. Loscalzo. Biochemistry of nitric oxide and its redox-activated forms. Science 258: 1896-1902, 1992.
27. c,i in lung and skeletal muscle. J. Appl. Physiol. 61: 127-132, 1986.
28. Von Euler, U. S., and G. Liljestrand. Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol. Scand. 21: 301-320, 1946.
29. Weir, E. K., and S. L. Archer. The mechanism of acute hypoxic pulmonary vasoconstriction: the tale of two channels. FASEB J. 9: 183-189, 1995.
30. Weissmann, N., F. Grimminger, D. Walmrath, and W. Seeger. Hypoxic vasoconstriction in buffer-perfused rabbit lungs. Respir. Physiol. 100: 159-169, 1995.
31. Whorton, A. R., D. B. Simonds, and C. A. Piantadosi. Regulation of nitric oxide synthesis by oxygen in vascular endothelial cells. Am. J. Physiol. 272 (Lung Cell. Mol. Physiol. 16): L1155-L1160, 1997.
32. Youngson, C., C. Nurse, H. Yeger, and E. Cutz. Oxygen sensing in airway chemoreceptors. Nature 365: 153-155, 1993.