Bound Tris confounds the identification of binding site residues in a paraquat single chain antibody

Journal of Biochemistry

Volumn 122, Issue 1, 1997, Pages 101-108

  Bowles, Mark R ^a   Mulhern, Terrence D ^b,c   Gordon, Ross B ^a   Inglis, Hayley R ^a,d   Sharpe, Iain A ^a   Cogill, Jan L ^a   Pond, Susan M ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b CSIRO   (Australia)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Antibody antigen interactions; Murine antibody; Nuclear magnetic resonance; Paraquat (1,1' dimethyl 4,4' bipyridinium dichloride); pH dependence; Single chain antibody; Site directed mutagenesis

Indexed keywords

ANTIBODY; DRUG ANTIBODY; PARAQUAT; TYROSINE;

ANTIBODY STRUCTURE; ANTIGEN ANTIBODY REACTION; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; IMMUNOTHERAPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARAQUAT POISONING; PH; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

MURINAE;

EID: 0030806346     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a021716     Document Type: Article

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