Association between cellular response (IL-4) to RESA/Pf155 and protection from clinical malaria among Papua New Guinean children living in a malaria endemic area

Parasite Immunology

Volumn 19, Issue 6, 1997, Pages 249-254

  Al Yaman, F ^a,b   Genton, B ^a   Taraika, J ^a   Anders, R ^c   Alpers, M P ^a  

^a PAPUA NEW GUINEA INSTITUTE OF MEDICAL RESEARCH   (Papua New Guinea)

^b AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Cellular immunity; IFN ; IL 4; Malaria; Plasmodium falciparum; Proliferation; RESA

Indexed keywords

ADOLESCENT; ANTIGEN DETECTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR IMMUNITY; CHILD; ENDEMIC DISEASE; FEMALE; GENETIC REGULATION; HUMAN; IMMUNOGENICITY; INFANT; MAJOR CLINICAL STUDY; MALARIA; MALE; MONONUCLEAR CELL; PAPUA NEW GUINEA; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTECTION; SCHIZONT; T LYMPHOCYTE ACTIVATION;

PLASMODIUM FALCIPARUM;

EID: 0030806284     PISSN: 01419838     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3024.1997.d01-204.x     Document Type: Article

References (27)

1. Alpers M.P., Al-Yaman F., Beck H.-P. et al. (1992) The Malaria vaccine epidemiology and evaluation project of Papua New Guinea: rationale and baseline studies. Papua New Guinea Medical Journal 35, 285-297
2. Al-Yaman F., Genton B., Anders R.F. et al. (1994) Relationship between humoral response to Plasmodium falciparum surface antigen 2 and malaria morbidity in a highly endemic area of Papua New Guinea. American Journal of Tropical Medicine and Hygiene 51, 593-602
3. Al-Yaman F., Genton B., Falk M. et al. (1995a) Humoral response to Plasmodium falciparum ring-infected erythrocyte surface antigen in a highly endemic area of Papua New Guinea. American Journal of Tropical Medicine and Hygiene 52, 66-71
4. Al-Yaman F., Genton B., Anders R., Taraika J., Ginny M., Mellor S. & Alpers M.P. (1995b) Assessment of the role of humoral response to Plasmodium falciparum MSP2 compared to RESA and SPf66 in protecting Papua New Guinean children from clinical malaria. Parasite Immunology 17, 493-501
5. Astagneau P., Lepers J.P., Chougnet C., Gandebout C., Andriamangatiana-Rason M.D., Larouzé B. & Deloron P. (1991) Assessment of the protective value of antibodies to the Plasmodium falciparum ring-infected erythrocyte surface antigen (RESA): an epidemiologic study in Madagascar. American Journal of Epidemiology 133, 177-184
6. Beck H-P., Felger I., Genton B., Alexander N., Al-Yaman F., Anders R. & Alpers M.P. (1995) Humoral and cell-mediated immunity to the Plasmodium falciparum ring-infected erythrocyte surface antigen in an adult population exposed to highly endemic malaria. Infection and Immunity 63, 596-600
7. Chang S., Kramer K., Yamaga K., Kato A., Case S. & Siddiqui W. (1988) Plasmodium falciparum: gene structure and hydropathy profile of the major merozoite surface antigen (gp195) of the Uganda Palo Alto isolate. Experimental Parasitology 67, 1-11
8. Chougnet C., Deloron P., Lepers J.P. et al. (1990a) Humoral and cell-mediated immune responses to the Plasmodium falciparum antigens Pf155/RESA and CS protein: seasonal variations in a population recently exposed to endemic malaria. American Journal of Tropical Medicine and Hygiene 43, 234-242
9. Chougnet C., Deloron P., Lepers J.P., Rason M.D., Savel J. & Coulanges P. (1990b) Longitudinal study of the cellular response to Pf155/RESA and CS protein in Madagascar. Immunology Letters 25, 231-236
10. Chumpitazi B.F.F., Deloron, P., Peyron F., Boudin C., Picot S. & Ambroise-Thomas P. (1991) Relationship between clinical protection and antibodies to Plasmodium falciparum RESA (ring-infected erythrocyte surface antigen) peptides. International Journal of Parasitology 21, 271-274
11. Collins W.E., Anders R.F., Pappaioanou M. et al. (1986) Immunization of Aotus monkey with recombinant proteins of an erythrocyte surface antigen of Plasmodium falciparum. Nature 323, 259-262
12. Culvenor J.G., Day K.P. & Anders R.F. (1991) Plasmodium falciparum ring-infected erythrocyte surface antigen is released from merozoite dense granules after erythrocyte invasion. Infection and Immunity 59, 1183-1187
13. Fern J. & Good M.F. (1992) Promiscuous malaria peptide epitope stimulates CD45Ra T cells from perioheral blood of nonexposed donors. Journal of Immunology 148, 907-913
14. Genton B., Al-Yaman F., Beck H-P. et al. (1995a) The epidemiology of malaria in the Wosera Area, East Sepik province of Papua New Guinea, in preparation for vaccine trials. I. Malariometric indices and immunity. Annals of Tropical Medicine and Parasitology 89, 359-376
15. Genton B., Al-Yaman F., Beck H-P. et al. (1995b) The epidemiology of malaria in the Wosera Area, East Sepik province of Papua New Guinea, in preparation for vaccine trials. II. Mortality and morbidity. Annals of Tropical Medicine and Parasitology 89, 377-390
16. Ho M. & Webster H.K. (1990) T cell responses in acute falciparum malaria. Immunology Letters 25, 135-138
17. Kramer K.J., Kan S.C. & Siddiqui W.A. (1982) Concentration of Plasmodium falciparum-infected erythrocytes by density gradient centrifugation in Percoll. Journal of Parasitology 68, 336-337
18. Mvondo J.L. James M.A., Sulzer A.J. & Campbell C.C. (1992) Malaria and pregnancy in Cameroonian women. Naturally acquired antibody responses to asexual blood-stage antigens and the circumsporozoite protein of Plasmodium falciparum. Transactions of the Royal Society of Tropical Medicine and Hygiene 86, 486-490
19. Petersen E., Hogh B., Perlmann H. et al. (1989) An epidemiological study of humoral and cell-mediated immune response to Plasmodium falciparum antigen Pf155/RESA in adult Liberians. American Journal of Tropical Medicine and Hygiene 41, 386-394
20. Riley E.M. & Greenwood B.M. (1988) Measuring cellular responses to malaria antigens in endemic populations: epidemiological, parasitological and physiological factors which influence in vitro assays. Immunology Letters 25, 221-229
21. Riley E.M., Olerup O. & Troye-Blomberg M. (1991) The immune recognition of malaria antigens. Parasitology Today 7, 5-11
22. Riley E.M., Allen S.J., Troye-Blomberg M. et al. (1991) Association between immune recognition of the malaria vaccine candidate antigen PC155/RESA and resistance to clinical disease: a prospective study in a malaria-endemia region of West Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene 85, 436-443
23. Rzepczyk C., Ramasamy R., Ho P.C.L. et al. (1988) Identification of T epitopes within a potential Plasmodium falciparum vaccine antigen, a study of human lymphocyte responses to repeat and non-repeat regions of Pf155/RESA. Journal of Immunology 141, 3197-3202
24. Troye-Blomberg M., Olerup O., Larsson et al. (1991) Failure to detect MHC class II associations of the human immune response induced by repeated malaria infections to Plasmodium falciparum antigen Pf155/RESA. International Immunology 3, 1043-1051
25. Wahlgren M., Bjorkman A., Perlmann H., Berzin K. & Perlmann P. (1986) Anti-Plasmodium falciparum antibodies acquired by residents in a holoendemic area of Liberia during development of clinical immunity. American Journal of Tropical Medicine and Hygiene 35, 22-29
26. r 155,000 Plasmodium falciparum antigen efficiently inhibit merozoite invasion. Proceedings of the National Academy of Science, USA 81, 7912-7916
27. Warsame M., Perlmann H., Ali S., Hagi H., Farah S., Lebbad M & Bjorkman A. (1989) The seroreactivity against Pf155 (RESA) antigen in villagers from a mesoendemic area in Somalia. Tropical Medicine and Parasitology 40, 412-414