Synergistic action of vitamin C and amino acids on vitamin E in inhibition of the lipoperoxidation of linoleic acid in disperse systems

International Journal of Pharmaceutics

Volumn 155, Issue 2, 1997, Pages 251-261

  Carlotti, M Eugenia ^a   Gallarate, Marina ^a   Gasco, M Rosa ^a   Morel, Silvia ^a   Serafino, Anna ^a   Ugazio, Elena ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

Amino acids; Emulsions; Linoleic acid; Lipoperoxidation; Micellar solutions; Synergistic effect; Vitamin C; Vitamin E

Indexed keywords

ALANINE; ALPHA TOCOPHEROL; AMINO ACID; ANTIOXIDANT; ASCORBIC ACID; BUTYLAMINE; CYSTEINE; GLUTATHIONE; GLYCINE; LINOLEIC ACID; TRYPTOPHAN;

ANTIOXIDANT ACTIVITY; ARTICLE; DRUG POTENTIATION; EMULSION; LIPID PEROXIDATION; MICELLE; OXYGEN CONSUMPTION; PH; POTENTIOMETRIC TITRATION; PRIORITY JOURNAL;

EID: 0030805942     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(97)00168-3     Document Type: Article

References (22)

1. Allan A., Wood H.L. Copper-catalysed oxidation of linoleic acid in buffered aqueous solutions. I. Effect of ascorbic acid. J. Sci. Food Agric. 21:1970;282-289.
2. Allan J.C., Farag R.S., Crook E.M. The metal-catalyzed oxidation of aqueous emulsions of linoleic acid and trilinolein. J. Appl. Biochem. 1:1979;1-15.
3. Barclay L.C.R., Ingold K.U. Autoxidation of a model membrane. A comparison of the autoxidation of egg lecithin phosphatidylcholine in water and in chlorobenzene. J. Am. Chem. Soc. 93:1989;3103-3106.
4. Barclay L.R.C., Locke S.J., MacNeil J.M. The autoxidation of unsaturated lipids in micelles. Synergism of inhibitors vitamin C and E. Can. J. Chem. 61:1983;1288-1290.
5. Carlotti M.E., Gasco M.R., Trotta M., Morel S. Auto-oxidation of linoleic acid in cosmetic formulations. J. Soc. Cosmet. Chem. 42:1991;285-298.
6. Caselli M., Mangone A. Phase equilibria involving autoaggregate systems: partitioning of amino acids between a water saline solution and an organic phase containing reverse micelles. Ann. Chim. 82:1992;23-36.
7. Cillard J., Cillard P. Behaviour of α, γ and δ-tocopherols with linoleic acid in aqueous media. Journal of American Oil Chemical Society (JAOCS). 57:1980;39-42.
8. Cillard J., Cillard P. Inhibitors of the prooxidant activity of α-tocopherols. JAOCS. 63:1986;1165-1169.
9. El Tayar N., Tsai R-S, Carrupt P-A, Testa B. Octan-1-ol-water partition coefficients of zwitterionic -amino acids. Determination by centrifugal partition chromatography and factorization into steric/hydrophobic and polar components. J. Chem. Soc. Perkin Trans. 2:1992;79-84.
10. Farag R.S., Osman S.A., Hallabo S.A.S., Nasr A.A. Linoleic acid oxidation catalyzed by various amino acids and cupric ions in aqueous media. JAOCS. 55:1978;703-707.
11. Ikeda N., Fukuzumi K. Synergistic antioxidant effect of nucleic acids and tocopherols. JAOCS. 54:1977;360-366.
12. Kahledi M.G., Rodgers A.H. Micellar-mediated shifts of ionization constants of amino acids and peptides. Anal. Chim. Acta. 239:1990;121-128.
13. Kuehl F.A. Jr., Egan R.W. Prostaglandins, arachidonic acid, and inflammation. Science. 210:1980;978-984.
14. Marcuse R. The effect of some amino acids on the oxidation of linoleic acid and its methyl ester. JAOCS. 39:1962;97-103.
15. Niki E., Tadatoshi S., Kawakami A., Kamiya Y. Inhibition of oxidation of methyl linoleate in solution by vitamin E and vitamin C. J. Biol. Chem. 259:1984;4177-4182.
16. Plaa G.L., Witschi H. Chemicals, drugs and lipid peroxidation. Annu. Rev. Pharmacol. Toxicol. 16:1976;125-141.
17. Riisom T., Sims R.J., Fioriti J.A. Effect of amino acids on the autoxidation of safflower oil in emulsions. JAOCS. 57:1980;354-359.
18. Rousseau C., Richard C., Martin R. Synergy effects of glutathione and amino acids on the antioxidant efficiency of vitamins C and E in the induced oxidation of methyl linolenate. J. Chem. Phys. 85:1988;145-146.
19. Rousseau-Richard C., Richard C., Martin R. Effets de synergie de la vitamine C et d'acides amines sur les proprietes antioxydantes de la vitamine E. New J. Chem. 15:1991;283-291.
20. Ruiz J.J., Aldaz A., Dominguez M. Can. J. Chem. 55:1977;2784-2799.
21. Salomon J.A., Smith D.R., Flower R.J., Moncada S., Vane J.R. Biochim. Biophys. Acta. 523:1978;250-262.
22. Siechowski J. Kinetics of antioxidative properties of aminoacids in olive oil. La Rivista Italiana delle Sostanze Grasse. 68:1970;365-369.