Adenosine stimulates nitric oxide synthesis in vascular smooth muscle cells

Cardiovascular Research

Volumn 35, Issue 1, 1997, Pages 168-174

  Ikeda, Uichi ^a   Kurosaki, Kenji ^a   Ohya, Ken Ichi ^a   Shimada, Kazuyuki ^a  

^a JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Adenosine; cAMP; Interleukin 1; Nitric oxide; Rat; Vascular smooth muscle cell

Indexed keywords

2 CHLOROADENOSINE; 8 (3,4 DIMETHOXYSTYRYL) 7 METHYL 1,3 DIPROPYLXANTHINE; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; BUCLADESINE; CYCLIC AMP; INTERLEUKIN 1; INTERLEUKIN 1BETA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL CELL; ARTICLE; CELL CULTURE; ENZYME IMMUNOASSAY; GENE EXPRESSION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

2-CHLOROADENOSINE; ADENOSINE; ANIMALS; BUCLADESINE; CELLS, CULTURED; CYCLIC AMP; INTERLEUKIN-1; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; NITRITES; RATS; RATS, SPRAGUE-DAWLEY; STIMULATION, CHEMICAL; VASODILATOR AGENTS;

EID: 0030805216     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0008-6363(97)00068-0     Document Type: Article

References (42)

1. Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:109-140.
2. Nathan C, Xie Q. Regulation of biosynthesis of nitric oxide. J Biol Chem 1994;269:13725-13728.
3. Ikeda U, Maeda Y, Kawahara Y, Yokoyama M, Shimada K. Angiotensin II augments cytokine-stimulated nitric oxide synthesis in rat cardiac myocytes. Circulation 1995;92:2683-2689.
4. Koide M, Kawahara Y, Tsuda T, Yokoyama M. Cytokine-induced expression of an inducible type of nitric oxide synthase gene in cultured vascular smooth muscle cells. FEBS Lett 1993;318:213-217.
5. Dinerman JL, Lowenstein CJ, Snyder SH. Molecular mechanisms of nitric oxide regulation. Circ Res 1993;73:217-222.
6. Hansson GK, Geng Y, Holm J, Hårdhammar P, Wennmalm Å, Jennische E. Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J Exp Med 1994;180:733-738.
7. Bobik A, Campbell JH. Vascular derived growth factors: cell biology, pathophysiology and pharmacology. Pharmacol Rev 1993;45:1-42.
8. Gordon EL, Pearson JD, Dickinson ES, Moreau D, Slakey LL. The hydrolysis of extracellular adenine nucleotides by arterial smooth muscle cells: regulation of adenosine production at the cell surface. J Biol Chem 1989;264:18986-18995.
9. Pearson JD, Gordon JL. Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides. Nature 1979;281:384-386.
10. Headrick JP, Berne RM. Endothelium-dependent and -independent relaxations to adenosine in guinea pig aorta. Am J Physiol 1990;259:H62-H67.
11. Cristalli G, Vittori S, Thompson RD, et al. Inhibition of platelet aggregation by adenosine receptor antagonists. Naunyn-Schmiedebergs Arch Pharmacol 1994;349:644-650.
12. Cronstein BN. Adenosine, an endogenous anti-inflammatory agent. J Appl Physiol 1994;76:5-13.
13. Jackson EK. Adenosine: a physiological brake on renin release. Annu Rev Pharmacol Toxicol 1991;31:1-35.
14. Murray RD, Churchill PC. Effects of adenosine receptor agonists in the isolated perfused rat kidney. Am J Physiol 1984;247:H343-H348.
15. Dubey RK, Gillespie DG, Osaka K, Suzuki F, Jackson EK. Adenosine inhibits growth of rat aortic smooth muscle cells. Hypertension 1996;27:786-793.
16. Dalzierl HH, Westfall DP. Receptors for adenine nucleotides and nucleosides: subclassification, distribution, and molecular characterization. Pharmacol Rev 1994;46:449-466.
17. Fredholm BB, Abbracchio MP, Burnstock G, et al. Nomenclature and classification of purinoceptors. Pharmacol Rev 1994;46:143-156.
18. Van Calker D, Müller M, Hamprecht B. Adenosine regulates, via two different types of receptors, the accumulation of cyclic AMP in cultured brain cells. J Neurochem 1979;33:999-1005.
19. 2 receptors. Trends Pharmacol Sci 1991;12:326-328.
20. 3 adenosine receptor. Proc Natl Acad Sci USA 1992;89:7432-7436.
21. Anand-Srivastava MB, Franks DJ, Cantin M, Genest J. Presence of 'Ra' and 'P' site receptors for adenylate cyclase in cultured vascular smooth muscle cells. Biochem Biophys Res Commun 1982;108:213-219.
22. Jonzon B, Nilsson J, Fredholm BB. Adenosine receptor-mediated changes in cyclic AMP production and DNA synthesis in cultured arterial smooth muscle cells. J Cell Physiol 1985;124:451-456.
23. Silver PJ, Walus K, DiSalvo J. Adenosine-mediated relaxation and activation of cyclic AMP-dependent protein kinase in coronary arterial smooth muscle. J Pharmacol Exp Ther 1984;228:342-347.
24. 2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide. Br J Pharmacol 1993;109:424-429.
25. Steinhorn RH, Morin FC, Van Wylen DG, Gugino SF, Giese E, Russell JA. Endothelium-dependent relaxations to adenosine in juvenile rabbit pulmonary arteries and veins. Am J Physiol 1994;266:H2001-H2006.
26. Ikeda U, Ikeda M, Oohara T, et al. Interleukin 6 stimulates growth of vascular smooth muscle cells in a PDGF-dependent manner. Am J Physiol 1991;260:H1713-H1717.
27. Knowles RG, Noncada S. Nitric oxide synthase in mammals. Biochem J 1994;298:249-258.
28. 15N]nitrate in biological fluids. Anal Biochem 1982;126:131-138.
29. Koide M, Kawahara Y, Nakayama I, Tsuda T, Yokoyama M. Cyclic AMP-elevating agents induce an inducible type of nitric oxide synthase in cultured vascular smooth muscle cells. J Biol Chem 1993;268:24959-24966.
30. Imai T, Hirata Y, Kanno K, Marumo F. Induction of nitric oxide synthase by cyclic AMP in rat vascular smooth muscle cells. J Clin Invest 1994;93:543-549.
31. Hirokawa K, O'Shaughnessy K, Moore K, Ramrakha P, Wilkins MR. Induction of nitric oxide synthase in cultured vascular smooth muscle cells: the role of cyclic AMP. Br J Pharmacol 1994;112:396-402.
32. 2 receptors in rat brain. J Pharmacol Exp Ther 1989;251:888-893.
33. 3-selective adenosine agonists. J Med Chem 1994;37:636-646.
34. 3 receptors. J Clin Invest 1996;98:1773-1779.
35. 2 receptor antagonist, to rat brain membranes. Mol Pharmacol 1994;46:817-822.
36. Gurden MF, Coates J, Ellis F, et al. Functional characterization of three adenosine receptor types. Br J Pharmacol 1993;109:693-698.
37. Oddis CV, Simmons RL, Hattler BG, Finkel MS. cAMP enhances inducible nitric oxide synthase mRNA stability in cardiac myocytes. Am J Physiol 1995;269:H2044-H2050.
38. Joly GA, Schini VB, Vanhoutte PM. Balloon injury and interleukin-1β induce nitric oxide synthase activity in rat carotid arteries. Circ Res 1992;71:331-338.
39. Buttery LD, Springall DR, Chester AH, et al. Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite. Lab Invest 1996;75:77-85.
40. Lloyd-Jones D, Bloch KD. The vascular biology of nitric oxide and its role in atherogenesis. Annu Rev Med 1996;47:365-375.
41. Yan Z, Yokota T, Zhang W, Hansson GK. Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery. Circ Res 1996;79:38-44.
42. Hamon M, Vallet B, Bauters C, et al. Long-term oral administration of L-arginine reduces intimal thickening and enhances neoendothelium-dependent acetylcholine-induced relaxation after arterial injury. Circulation 1994;90:1357-1362.