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Volumn 7, Issue 5, 1997, Pages 350-356

Heterocyclic amines, cytochrome P4501A2, and N-acetyltransferase: Issues involved in incorporating putative genetic susceptibility markers into epidemiological studies

Author keywords

Cytochrome P4501A2; Genotype; Heterocyclic Amines; Inducible Enzymes; N acetyltransferase MelQx; Phenotype

Indexed keywords

ACYLTRANSFERASE; CYTOCHROME P450; HETEROCYCLIC AMINE;

EID: 0030805080     PISSN: 10472797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1047-2797(97)00027-6     Document Type: Article
Times cited : (11)

References (30)
  • 1
    • 0024405095 scopus 로고
    • Hepatocarcinogenic heterocyclic aromatic amines that induce cytochrome P-448 isozymes, mainly cytochrome P-448H (P-4501A2), responsible for mutagenic activation of the carcinogenesis in rat liver
    • Degawa M, Tanimura S, Agatsuma T, Hashimoto Y. Hepatocarcinogenic heterocyclic aromatic amines that induce cytochrome P-448 isozymes, mainly cytochrome P-448H (P-4501A2), responsible for mutagenic activation of the carcinogenesis in rat liver. Carcinogenesis. 1989;10:1119-1122.
    • (1989) Carcinogenesis , vol.10 , pp. 1119-1122
    • Degawa, M.1    Tanimura, S.2    Agatsuma, T.3    Hashimoto, Y.4
  • 2
    • 0026040316 scopus 로고
    • Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon
    • Turesky RJ, Lang NP, Butler MA, Teitel CH, Kadlubar FF. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon. Carcinogenesis. 1991;12:1839-1845.
    • (1991) Carcinogenesis , vol.12 , pp. 1839-1845
    • Turesky, R.J.1    Lang, N.P.2    Butler, M.A.3    Teitel, C.H.4    Kadlubar, F.F.5
  • 4
    • 0001360416 scopus 로고    scopus 로고
    • Genetic polymorphisms and the risk of cancer. A review of the literature
    • D'Errico A, Taioli E, Chenx X, Vineis P. Genetic polymorphisms and the risk of cancer. A review of the literature. Biomarkers. 1996;1:149-173.
    • (1996) Biomarkers , vol.1 , pp. 149-173
    • D'Errico, A.1    Taioli, E.2    Chenx, X.3    Vineis, P.4
  • 5
    • 0027999623 scopus 로고
    • Rapid metabolic phenotypes for acetyl-transferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increases the risk for colorectal cancer or polyps
    • Lang NP, Butler MA, Massengill J, Lawson M, Stotts RC, Hauser-Jensen M, and Kadlubar FF. Rapid metabolic phenotypes for acetyl-transferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increases the risk for colorectal cancer or polyps. Cancer Epidemiol Biomarkers Prev. 1994;3:675-682.
    • (1994) Cancer Epidemiol Biomarkers Prev , vol.3 , pp. 675-682
    • Lang, N.P.1    Butler, M.A.2    Massengill, J.3    Lawson, M.4    Stotts, R.C.5    Hauser-Jensen, M.6    Kadlubar, F.F.7
  • 7
    • 0026240006 scopus 로고
    • Relevance of metabolic polymorphisms to human carcinogenesis: Evaluation of epidemiologic evidence
    • Caporaso N, Landi MT, Vineis P. Relevance of metabolic polymorphisms to human carcinogenesis: Evaluation of epidemiologic evidence. Pharmacogenetics. 1991;1:4-19.
    • (1991) Pharmacogenetics , vol.1 , pp. 4-19
    • Caporaso, N.1    Landi, M.T.2    Vineis, P.3
  • 8
    • 0001680211 scopus 로고
    • Cytochrome P450 enzymes
    • Guengerich FP. Cytochrome P450 enzymes. American Scientist. 1993;81:440-447.
    • (1993) American Scientist , vol.81 , pp. 440-447
    • Guengerich, F.P.1
  • 9
    • 0026507870 scopus 로고
    • Human cytochrome P-450 enzymes
    • Guengerich FP. Human cytochrome P-450 enzymes. Life Sci. 1992; 50:1471-1478.
    • (1992) Life Sci , vol.50 , pp. 1471-1478
    • Guengerich, F.P.1
  • 10
    • 0026651273 scopus 로고
    • Human cytochromes P450: Problems and prospects
    • Gonzalez FJ. Human cytochromes P450: Problems and prospects. Trends Pharmacol Sci. 1992;13:346-351.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 346-351
    • Gonzalez, F.J.1
  • 11
    • 0027960793 scopus 로고
    • Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans
    • Sinha R, Rothman N, Brown E, Mark S, Hoover R, Caporaso N, Levander O, Knize M, Lang N, Kadlubar F. Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans. Cancer Res. 1994;54:6154-6159.
    • (1994) Cancer Res , vol.54 , pp. 6154-6159
    • Sinha, R.1    Rothman, N.2    Brown, E.3    Mark, S.4    Hoover, R.5    Caporaso, N.6    Levander, O.7    Knize, M.8    Lang, N.9    Kadlubar, F.10
  • 12
    • 0027751126 scopus 로고
    • Specific induction of hepatic cytochrome P4501a-2 in C57BL/6 and DBA/2 mice treated with 2-amino-3-methylimidazo[4, 5-f]quinolin (IQ)
    • Nerurkar PV, Anderson LM, Snyderwine EG, Park SS, Thorgeirsson SS, Rice JM. Specific induction of hepatic cytochrome P4501a-2 in C57BL/6 and DBA/2 mice treated with 2-amino-3-methylimidazo[4, 5-f]quinolin (IQ). J Biochem Toxicol. 1993;8:175-186.
    • (1993) J Biochem Toxicol , vol.8 , pp. 175-186
    • Nerurkar, P.V.1    Anderson, L.M.2    Snyderwine, E.G.3    Park, S.S.4    Thorgeirsson, S.S.5    Rice, J.M.6
  • 13
    • 0028336794 scopus 로고
    • Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: Absence of mutation prescribing the phenotype in the CYP1A2 gene
    • Nakajima MT, Yokoi M, Mizutami SS, Kadlubar FF, Kamataki T. Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: Absence of mutation prescribing the phenotype in the CYP1A2 gene. Cancer Epidemiol Biomarkers Prev. 1994;3: 413-421.
    • (1994) Cancer Epidemiol Biomarkers Prev , vol.3 , pp. 413-421
    • Nakajima, M.T.1    Yokoi, M.2    Mizutami, S.S.3    Kadlubar, F.F.4    Kamataki, T.5
  • 15
    • 0021813284 scopus 로고
    • N-acetylation pharmacogenetics
    • Weber WW, Hein DW. N-acetylation pharmacogenetics. Physiol Rev. 1985;37:25-79.
    • (1985) Physiol Rev , vol.37 , pp. 25-79
    • Weber, W.W.1    Hein, D.W.2
  • 16
    • 0026447831 scopus 로고
    • Intra-and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef
    • Lynch AM, Knize MG, Boobis AR, Gooderham NJ, Davies DS, Murray S. Intra-and interindividual variability in systemic exposure in humans to 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, carcinogens present in cooked beef. Cancer Nurs. 1992;52:6216-6223.
    • (1992) Cancer Nurs , vol.52 , pp. 6216-6223
    • Lynch, A.M.1    Knize, M.G.2    Boobis, A.R.3    Gooderham, N.J.4    Davies, D.S.5    Murray, S.6
  • 17
    • 0028069430 scopus 로고
    • CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans
    • Boobis AR, Lynch AM, Murray S, et al. CYP1A2-catalyzed conversion of dietary heterocyclic amines to their proximate carcinogens is their major route of metabolism in humans. Cancer Res. 1994;54:89-94.
    • (1994) Cancer Res , vol.54 , pp. 89-94
    • Boobis, A.R.1    Lynch, A.M.2    Murray, S.3
  • 18
    • 0028850262 scopus 로고
    • High concentrations of carcinogen PhIP occurs in chicken but are dependent on the cooking method
    • Sinha R, Rothman N, Brown ED, et al. High concentrations of carcinogen PhIP occurs in chicken but are dependent on the cooking method. Cancer Res. 1995;55:4516-4519.
    • (1995) Cancer Res , vol.55 , pp. 4516-4519
    • Sinha, R.1    Rothman, N.2    Brown, E.D.3
  • 20
    • 0020431144 scopus 로고
    • Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G.H.A. Clowes Memorial Lecture
    • Conney AH. Induction of microsomal enzymes by foreign chemicals and carcinogenesis by polycyclic aromatic hydrocarbons: G.H.A. Clowes Memorial Lecture. Cancer Res. 1982;42:4875-4917.
    • (1982) Cancer Res , vol.42 , pp. 4875-4917
    • Conney, A.H.1
  • 22
    • 0028304678 scopus 로고
    • Assessment of cytochrome P4502E1 induction in alcoholic patients by choroxazone pharmacokinetics
    • Girre C, Lucas D, Hispard E, Menez C, Dally S, Menez JF. Assessment of cytochrome P4502E1 induction in alcoholic patients by choroxazone pharmacokinetics. Biochem Pharmacol. 1994;47:1503-1508.
    • (1994) Biochem Pharmacol , vol.47 , pp. 1503-1508
    • Girre, C.1    Lucas, D.2    Hispard, E.3    Menez, C.4    Dally, S.5    Menez, J.F.6
  • 23
    • 0029999726 scopus 로고    scopus 로고
    • Predictors of N-acetyl-transferase activity: Should caffeine phenotyping and NAT2 genotyping be used interchangeably in epidemiological studies?
    • Le Marchand L, Sivaraman L, Franke AA, et al. Predictors of N-acetyl-transferase activity: Should caffeine phenotyping and NAT2 genotyping be used interchangeably in epidemiological studies? Cancer Epidemiol Biomarkers Prev. 1996;5:449-455.
    • (1996) Cancer Epidemiol Biomarkers Prev , vol.5 , pp. 449-455
    • Le Marchand, L.1    Sivaraman, L.2    Franke, A.A.3
  • 24
    • 0027136288 scopus 로고
    • Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
    • Johansson I, Lundqvist E, Bertilsson L, Dahl ML, Sjoqvist F, Ingelman-Sundberg M. Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine [see comments]. Proc Natl Acad Sci USA. 1993; 15;90:11825-11829.
    • (1993) Proc Natl Acad Sci USA , vol.15 , Issue.90 , pp. 11825-11829
    • Johansson, I.1    Lundqvist, E.2    Bertilsson, L.3    Dahl, M.L.4    Sjoqvist, F.5    Ingelman-Sundberg, M.6
  • 26
    • 0028336745 scopus 로고
    • Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva
    • Fuhr U, Rost KL. Simple and reliable CYP1A2 phenotyping by the paraxanthine/caffeine ratio in plasma and in saliva. Pharmacogenetics. 1994;4:109-116.
    • (1994) Pharmacogenetics , vol.4 , pp. 109-116
    • Fuhr, U.1    Rost, K.L.2
  • 27
    • 0024350591 scopus 로고
    • Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism - Hypothesis testing
    • Jackson PR, Tucker GT, Woods HF. Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism - hypothesis testing. Br J Clin Pharmacol. 1989;28:655-662.
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 655-662
    • Jackson, P.R.1    Tucker, G.T.2    Woods, H.F.3
  • 28
    • 0018900001 scopus 로고
    • A family and population study of genetics polymorphism of debrisoquin hydroxylase in a white British population
    • Evans DAP, Mahgoub A, Sloan TP, Idle JR, Smith RL. A family and population study of genetics polymorphism of debrisoquin hydroxylase in a white British population. J Med Genet. 1980;17:102-105.
    • (1980) J Med Genet , vol.17 , pp. 102-105
    • Evans, D.A.P.1    Mahgoub, A.2    Sloan, T.P.3    Idle, J.R.4    Smith, R.L.5
  • 29
    • 0024352671 scopus 로고
    • Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism - Histograms and probit plots
    • Jackson PR, Tucker GT, Woods HF. Testing for bimodality in frequency distributions of data suggesting polymorphisms of drug metabolism - histograms and probit plots. Br J Clin Pharmacol. 1989;28: 647-663.
    • (1989) Br J Clin Pharmacol , vol.28 , pp. 647-663
    • Jackson, P.R.1    Tucker, G.T.2    Woods, H.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.