Insights into the mechanism of the β-elimination catalyzed by the N-terminal domain of DNA polymerase β

Tetrahedron

Volumn 53, Issue 35, 1997, Pages 12057-12066

  Mullen, Gregory P ^a   Antuch, Walfrido ^a   Maciejewski, Mark W ^a   Prasad, Rajendra ^b   Wilson, Samuel H ^b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE BETA;

CONFERENCE PAPER; ENZYME ACTIVITY; ENZYME STRUCTURE; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; REACTION ANALYSIS;

EID: 0030804836     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(97)00768-0     Document Type: Conference Paper

References (22)

1. Kumar, A.; Widen, S. G.; Williams, K. R.; Kedar, P.; Karpel, R. L.; Wilson, S. H. J. Biol. Chem. 1990, 265, 2124-2131.
2. Casas-Finet, J. R.; Kumar, A.; Morris, G.; Wilson, S. H.; Karpel, R. L. J. Biol. Chem. 1991, 266, 19618-19625.
3. Kumar, A.; Abbotts, J.; Karawya, E. M.; Wilson, S. H. Biochemistry 1990, 29, 7156-7159.
4. Prasad, R.; Beard W. A.; Wilson, S. H. J. Biol. Chem. 1994, 269, 18096-18101.
5. Matsumoto, Y.; Kim, K. 1995, Science 269, 699-702.
6. Liu, D-J.; DeRose, E. F.; Prasad, R.; Wilson, S. H.; Mullen, G. P. Biochemistry 1994, 33, 9537-9545 .
7. Liu, D-J.; DeRose, E. F.; Prasad, R.; Wilson, S. H.; Mullen, G. P. Biochemistry 1996, 35, 6188-6200.
8. Mullen, G. P.; Wilson, S. H. Biochemistry 1997, 4713-4717.
9. Thayer, M. M.; Ahern, H.; Xing, D.; Cunningham, R. P.; Tainer, J. A. EMBO J. 1995, 14, 4108-4120.
10. Labahn, J.; Schärer, O. D.; Long, A.; Ezaz-Nikpay, K.; Verdine, G. L.; Ellenberger, T. E. Cell 1996, 86, 321-329. Yamagata, Y.; Kato, M.; Odawara, K.; Tokuno, Y.; Nakashima, Y.; Matsushima, N.; Yasumura, K.; Tomita, K.; Ihara, K.; Fujii, Y.; Nakabeppu, Y.; Sekiguchi, M.; Fujii, S. Cell 1996, 86, 311-319.
11. Labahn, J.; Schärer, O. D.; Long, A.; Ezaz-Nikpay, K.; Verdine, G. L.; Ellenberger, T. E. Cell 1996, 86, 321-329. Yamagata, Y.; Kato, M.; Odawara, K.; Tokuno, Y.; Nakashima, Y.; Matsushima, N.; Yasumura, K.; Tomita, K.; Ihara, K.; Fujii, Y.; Nakabeppu, Y.; Sekiguchi, M.; Fujii, S. Cell 1996, 86, 311-319.
12. Seeberg, E.; Eide, L.; Bjørås, M. Trends Biochem. Sci. 1995, 20, 391-397.
13. Mullen, G. P.; Wilson, S. H. Repair Activity in DNA Polymerases: A Structurally Conserved Helix-hairpin-helix Motif in Base Excision Repair Enzymes and in DNA Polymerase β, in Base Excision Repair of DNA Damage, Ian D. Hickson, Ed.; Landes Bioscience, Springer-Verlag, 1997; pp. 121-135.
14. Piersen, C. E., Prasad, R., Wilson, S. H., Lloyd, R. S. J. Biol. Chem. 1996, 271, 17811-17815.
15. Hilbert, T. P., Boorstein, R. J., Kung, H. C., Bolton, P. H., Xing, D., Cunningham, R. P., & Teebor, G. W. Biochemistry, 1996, 35, 2505-2511.
16. O'Handley, S.; Scholes, C. P.; Cunningham, R. P. Biochemistry 1995, 34, 2528-2536.
17. Bax, A.; Davis, D. G. J. Magn. Reson. 1985, 65, 355-360.
18. Kay, L. E.; Keifer, P.; Saarinen, T. J. Am. Chem. Soc. 1992, 114, 10663-10665.
19. Bartels, C.; Xia, T.; Billeter, M.; Güntert, P.; Wüthrich, K. J. Biomol. NMR 1995, 6, 1-10.
20. Szyperski, T; Antuch, W.; Schick, M.; Betz, A.; Stone, S. R.; Wüthrich, K. Biochemistry, 1994, 33, 9303-9310.
21. Basu, A.; Kedar, P.; Wilson, S. H.; Modak, M. J. Biochemistry 1989, 28, 6305-6309.
22. Mazumder, A.; Gerlt, J. A.; Absalon, M. J.; Stubbe, J.; Cunningham R. P.; Withka, J.; Bolton, P. H. Biochemistry 1991, 30, 1119-1126.