Peptide nucleic acid (PNA) is capable of enhancing hammerhead ribozyme activity with long but not with short RNA substrates

Nucleic Acids Research

Volumn 25, Issue 14, 1997, Pages 2690-2693

  Jankowsky, Eckhard ^a,c   Strunk, Günther ^b   Schwenzer, Bernd ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^c New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; PEPTIDE NUCLEIC ACID; RIBOZYME; RNA;

ARTICLE; ENZYME ACTIVITY; ENZYME SUBSTRATE; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

HUMANS; OLIGODEOXYRIBONUCLEOTIDES; RNA; RNA, CATALYTIC; SUBSTRATE SPECIFICITY;

EID: 0030804765     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.14.2690     Document Type: Article

References (26)

1. Uhlenbeck, O.C. (1987) Nature 328, 596-600.
2. Symons, R.H. (1992) Annu. Rev. Biochem. 61, 614-671.
3. Haseloff, J. and Gerlach, W. (1988) Nature 334, 585-591.
4. Sarver, N., Cantin, E.M., Chang, P.S., Zaia, J.A., Ladne, P.A., Stephens, D.A. and Rossi, J.J. (1990) Science 247, 1222-1224.
5. Marschall, P., Thomson, J.B. and Eckstein, F. (1994) Cell. Mol. Neurobiol. 14, 523-537.
6. Heidenreich, O. and Eckstein, F. (1992) J. Biol. Chem. 267, 1904-1909.
7. Rossi, J.J. (1993) Methods 5, 1-5.
8. Müller, G., Strack, B., Danull, J., Sproat, B.S., Surovoy, A., Jung, G. and Moelling, K. (1994) J. Mol. Biol. 242, 422-429.
9. Mahieu, M., Hendrix, C., Ooms, J., Herdewijn, P. and Content, J. (1995) Biochem. Biophys. Res. Commun. 214, 36-43.
10. Goodchild, J. (1992) Nucleic Acids Res. 20, 4607-4612.
11. Perkins, T.A., Wolf, D.E. and Goodchild, J. (1996) Biochemistry 35, 16370-16377.
12. Denman, R. (1993) Nucleic Acids Res. 21, 4119-4125.
13. Denman, R. (1996) FEBS Lett. 382, 116-121.
14. Jankowsky, E. and Schwenzer, B. (1996) Biochemistry 35, 15313-15321.
15. Scarabino, D. and Tocchini-Valentini, G.P. (1996) FEBS Lett. 383, 185-190.
16. Nielsen, P.E., Egholm, M., Berg, R.H. and Buchardt, O. (1991) Science 214, 1497-1500.
17. Egholm, M., Buchhardt, O., Christensen, L., Behrens, C., Freier, S.M., Driver, D.A., Berg, R.H., Kim, S.K., Nordén, B. and Nielsen, P.E. (1993) Nature 365, 566-568.
18. Demidov, V.V., Yanilovich, M.V., Belotserkovskii, B.P., Frank-Kamenetskii, M.D. and Nielsen, P.E. (1995) Proc. Natl. Acad. Sci. USA 92, 2637-2641.
19. Wittung, P., Nielsen, P. and Nordén. B. (1996) J. Am. Chem. Soc. 118, 7049-7054.
20. Knudsen, H. and Nielsen, P.E. (1996) Nucleic Acids Res. 24, 494-500.
21. Jankowsky, E. and Schwenzer, B. (1996) Nucleic Acids Res. 24, 423-429.
22. Scarpati, E.M., Duanzhi, W., Broze, G.J., Miletich, J.P., Flandermeyer, R.R., Siegel, N.R. and Sadler, J.E. (1987) Biochemistry 26, 5234-5238.
23. Herschlag, D. (1991) Proc. Natl. Acad. Sci. USA 88, 6921-6925.
24. Bertrand, E., Pictet, R. and Grange, T. (1994) Nucleic Acids Res. 22, 293-300.
25. Woisard, A., Fourrey, J.L. and Favre, A. (1994) J. Mol. Biol. 239, 366-370.
26. Herschlag, D., Khosla, M., Tsuchihashi, Z. and Karpel, R.L. (1994) EMBO J. 13, 2913-2924.