Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization

Drug Metabolism and Disposition

Volumn 25, Issue 10, 1997, Pages 1165-1175

  Chien, Jenny Y ^b   Thummel, Kenneth E ^b   Slattery, John T ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; ISONIAZID; LIGAND; PARACETAMOL;

ARTICLE; CLINICAL TRIAL; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG MIXTURE; ENZYME ACTIVE SITE; ENZYME INDUCTION; ENZYME STABILITY; ENZYME SUBSTRATE; HUMAN; LIVER TOXICITY; PRIORITY JOURNAL; PROTEIN SYNTHESIS;

ACETAMINOPHEN; ANIMALS; COMPUTER SIMULATION; CYTOCHROME P-450 CYP2E1; DRUG INTERACTIONS; ENZYME ACTIVATION; ENZYME INDUCTION; HUMANS; ISONIAZID; LIVER; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 0030802792     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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