Brain, breathing and breathlessness

Respiration Physiology

Volumn 109, Issue 3, 1997, Pages 197-204

  Guz, A ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

Brain; Breathing; Breathlessness; Control of breathing; Higher centers; Mammals; Man; Perception; Speech

Indexed keywords

BRAIN REGION; DYSPNEA; HUMAN; MAMMAL; MOTOR CORTEX; NONHUMAN; PERCEPTION; PRIORITY JOURNAL; RESPIRATION CENTER; RESPIRATION CONTROL; REVIEW;

EID: 0030801691     PISSN: 00345687     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5687(97)00050-9     Document Type: Article

References (34)

1. Adams, L., Guz, A. (Eds.), 1996. Respiratory Sensation. Lung Biology in Health and Disease, vol. 90. Marcel Dekker, New York.
2. Aminoff, M.J., Sears, T.A., 1971. Spinal integration of segmental, cortical and breathing inputs to thoracic respiratory motoneurones. J. Physiol. 215, 557-575.
3. CO2 in mechanically ventilated quadriplegics. Resp. Physiol. 76, 53-67.
4. CO2 persists after complete neuromuscular block in humans. Respir. Physiol. 80, 1-18.
5. Chen, Z., Eldridge, F.L., Wagner, P.G., 1992. Respiratory associated thalamic activity is related to level of respiratory drive. Respir. Physiol. 90, 99-113.
6. Colebatch, J.G., Adams, L., Murphy, K., Martin, A.J., Lammertsma, A.A., Tochon-Danguy, H.J., Clark, J.C., Friston, K.J., Guz, A., 1991. Regional cerebral blood flow during volitional breathing in man. J. Physiol. 443, 91-103.
7. Colle, J., Massion, J., 1958. Effet de la stimulation du cortex moteur sur l'activite electrique des nerfs phreniques et medions. Arch. Physiol. Biochem. 66, 496-514.
8. Corfield, D.R., Morrell, M.J., Guz, A., 1995a. The nature of breathing during hypocapnia in awake man. Resp. Physiol. 101, 145-159.
9. 2-stimulated breathing in man. J. Physiol. 488, 77-84.
10. Datta, A.K., Shea, S.A., Horner, R.L., Guz, A., 1991. The influence of induced hypocapnoea and sleep on the endogenous respiratory rhythm in humans. J. Physiol. 440, 17-33.
11. Draper, M.H., Ladefoged, P., Whitteridge, D., 1959. Respiratory muscles in speech. J. Speech Hear Res. 2 (1), 16-27.
12. Fink, B.R., 1961. Influence of cerebral activity in wakefulness on regulation of breathing. J. Appl. Physiol. 16, 15-21.
13. Fink, G., Adams, L., Watson, J.D.G., Innes, J.A., Wuyam, B., Kobayashi, I., Corfield, D., Murphy, K., Jones, T., Frackowiak, R.S.J., Guz, A., 1995. Hyperpnoea during and immediately after exercise in man: evidence of motor cortical involvement. J. Physiol. 489, 663-675.
14. Foerster, O., 1936. Motorische Felder und Bahten. In: Bumke, O., Foerster, O. (Eds.), Handbuch der Neurologie. Springer, Berlin, pp. 50-51.
15. Gandevia, S.C., Rothwell, J.C., 1987. Activation of the human diaphragm from the motor cortex. J. Physiol. 384, 109-118.
16. Heywood, P., Murphy, K., Corfield, D.R., Morrell, M.J., Howard, R.S., Guz, A., 1996. Control of breathing in man; insights from the 'locked-in' syndrome. Resp. Physiol. 106, 13-20.
17. Krogh, A., Lindhard, J., 1913. The regulation of respiration and circulation during the initial stages of muscular work. J. Physiol. 47, 112-136.
18. Lahuerta, J., Buxton, P., Lipton, S., Bowsher, D., 1992. The location and function of respiratory fibres in the second cervical spinal cord segment: respiratory dysfunction syndrome after cervical cordotomy. J. Neurol. Neurosurg. Psychiatry 55, 1142-1145.
19. Maskill, D., Murphy, K., Mier, A., Owen, M., Guz, A., 1991. Motor cortical representation of the diaphragm in man. J. Physiol. 443, 105-121.
20. Munschauer, F.E., Mador, M.J., Ahuja, A., Jacobs, L., 1990. Selective paralysis of voluntary but not limbically influenced automatic respiration. Arch. Neurol. 48, 1190-1192.
21. Murphy, K., Corfield, D.R., Guz, A., Fink, G., Harrison, J., Wise, R.S.J., Adams, L., 1996. Cerebral areas associated with the motor control of speech. J. Appl Physiol. (in press).
22. Orem, J., Nettick, A., 1986. Behavioural control of breathing in the cat. Brain Res. 366, 238-253.
23. Orem, J., 1988. Neural basis of behavioural and state-dependent control of breathing. In: Lydic, R., Biebuy, K.J.F. (Eds.), Clinical Physiology of Sleep, American Physiological Society, Bethesda, MD, pp. 78-96.
24. Penfield, W., Rasmussen, T., 1950. Vocalization and speech arrest. In: The Cerebral Cortex of Man. A Clinical Study of Localization of Function, Chapter V. Macmillan, New York, pp. 88-108.
25. Planche, D., 1972. Effets de la stimulation du cortex cerebral sur l'activite du nerf phrenique. J. Physiol. 64, 51-56.
26. Plum, F., Leigh, R.J., 1981. Abnormalities of central mechanisms. In: Hornbeim, T.F. (Ed.), Regulation of Breathing, Part II, vol. 17. Lung Biology in Health and Disease. Marcel Dekker, New York, pp. 989-1067.
27. Ramsay, S.C., Adams, L., Murphy, K., Corfield, D.R., Grootoonk, S., Bailey, D.L., Frackowiak, R.S.J., Guz, A., 1993. Regional cerebral blood flow during volitional expiration in man. J. Physiol. 461, 85-101.
28. Severinghaus, J.W., Mitchell, R.A., 1962. Ondine's Curse -failure of respiratory centre automaticity while awake. Clin. Res. 10, 122.
29. 2. Resp. Physiol. 93, 203-219.
30. Shea, S.A., Andres, L.P., Shannon, D.C., Banzett, R.B., 1993b. Ventilatory responses to exercise in humans lacking ventilatory chemosensitivity. J. Physiol. 468, 623-640.
31. Simon, P.M., Schwartzstein, R.M., Weiss, J.W., Fencl, V., Teghtsoonian, M., Weinberger, S.E., 1990. Distinguishable types of dyspnoea in patients with shortness of breath. Am. Rev. Resp. Dis. 142, 1009-1014.
32. Somjen, G.G., 1992. The missing error signal-regulation beyond negative feedback. News Physiol. Sci. 7, 184-185.
33. Talbot, J.D., Marrett, S., Evans, A.C., Meyer, E., Bushnell, M.C., Duncan, G.H., 1991. Multiple representations of pain in human cerebral cortex. Science 251, 1355-1358.
34. Ullmann, E., 1970. The two original papers by Hering and Breuer submitted by Hering to the K.K. Akademie der Wissenschaften ZV Wien in 1868. In: Porter, R. (Ed.), Breathing: Hering-Breuer Centenary Symposium CIBA Foundation; Churchill Livingstone, Edinburgh, pp. 357-394.