Retinal changes associated with tamoxifen treatment for breast cancer

Eye

Volumn 11, Issue 3, 1997, Pages 295-297

  Tang, Rosa ^a   Shields, Jerry ^b   Schiffman, Jade ^a   Li, Helen ^a   Locher, Diana ^a   Hampton, James ^a   Prager, Thomas ^a   Pardo, Gabriel ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b WILLS EYE HOSPITAL   (United States)

Author keywords

Breast; Cancer; Retina; Tamoxifen

Indexed keywords

TAMOXIFEN; TAMOXIFEN CITRATE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; EYE TOXICITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; OUTCOMES RESEARCH; RETINA; RETINOPATHY; VISUAL IMPAIRMENT;

EID: 0030801476     PISSN: 0950222X     EISSN: None     Source Type: Journal    
DOI: 10.1038/eye.1997.64     Document Type: Article

References (16)

1. Fisher B, Constantino J, Redmond C, et al. A randomised clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. N Engl J Med 1989;320:479-84.
2. Kaiser-Kupfer M, Lippman M. Tamoxifen retinopathy. Cancer Treat Rep 1978;62:315-20.
3. Kaiser-Kupfer M, Kupfer C, Rodrigues M. Tamoxifen retinopathy: a clinicopathologic report. Ophthalmology 1981;88:89-93.
4. McKeown C, Swartz M, Blom J, Maggiano J. Tamoxifen retinopathy. Br J Ophthalmol 1981;65:177-9.
5. Vinding T, Nielsen N. Retinopathy caused by treatment with tamoxifen in low dosage. Acta Ophthalmolol (Copenh) 1983;61:45-50.
6. Pugesgaard T, Von Eyben F. Bilateral optic neuritis evolved during tamoxifen treatment. Cancer 1986;58: 383-6.
7. Griffiths M. Tamoxifen retinopathy at low dosage [letter]. Am J Ophthalmol 1987;104:185-6.
8. Ashford A, Donev I, Tiwari R, Garrett T. Reversible ocular toxicity related to tamoxifen therapy. Cancer 1988;61:33-5.
9. Gerner E. Ocular toxicity of tamoxifen. Ann Ophthalmol 1989;21:420-3.
10. Chern S, Danis R. Retinopathy associated with low-dose tamoxifen [letter]. Am J Ophthalmol 1993;116: 372-5.
11. Pavlidis N, Petris C, Briassoulis E, et al. Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity: a prospective study of 63 patients. Cancer 1992;69:2961-4.
12. Beck M, Mills P. Ocular assessment of patients treated with tamoxifen. Cancer Treat Rep 1979;63:1833-4.
13. Longstaff S, Sigurdsson H, O'Keeffe M, et al. A controlled study of ocular effects of tamoxifen in conventional dosage in the treatment of breast carcinoma. Eur J Cancer Clin Oncol 1989;25:1805-8.
14. Early Breast Cancer Trialists' Collaborative Group. Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. Lancet 1992;339: 71-85,115.
15. Heier J, Dragoo R, Enzenauer R, Waterhouse W. Screening for ocular toxicity in asymptomatic patients treated with tamoxifen. Am J Ophthalmol 1994;117: 772-5.
16. Flach A. Clear evidence that long-term, low-dose tamoxifen treatment can induce ocular toxicity: a prospective study of 63 patients [comment]. Surv Ophthalmol 1994;38:392-3.