메뉴 건너뛰기




Volumn 29, Issue 3, 1997, Pages 221-234

Oestrogen receptor variants and mutations in human breast cancer

Author keywords

Breast cancer; Mutations; Oestrogen receptor

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; MESSENGER RNA;

EID: 0030801460     PISSN: 07853890     EISSN: None     Source Type: Journal    
DOI: 10.3109/07853899708999340     Document Type: Review
Times cited : (30)

References (82)
  • 1
    • 0037837001 scopus 로고
    • Baltimore: Urban and Schwarzenberg
    • Vorherr H (ed.). Breast Cancer. Baltimore: Urban and Schwarzenberg, 1980.
    • (1980) Breast Cancer
    • Vorherr, H.1
  • 2
    • 0024410159 scopus 로고
    • Regulation of gene expression by nuclear hormone receptors
    • Ham J, Parker MG. Regulation of gene expression by nuclear hormone receptors. Curr Opin Cell Biol 1989; 1: 503-11.
    • (1989) Curr Opin Cell Biol , vol.1 , pp. 503-511
    • Ham, J.1    Parker, M.G.2
  • 3
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily
    • Tsai M-J, O'Malley BW. Molecular mechanisms of action of steroid/thyroid receptor superfamily. Annu Rev Biochem 1994; 63: 451-86.
    • (1994) Annu Rev Biochem , vol.63 , pp. 451-486
    • Tsai, M.-J.1    O'Malley, B.W.2
  • 5
    • 0024317270 scopus 로고
    • The human estrogen receptor has two independent nonacidic transcriptional activation functions
    • Tora L, White J, Brou C, et al. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 1989; 59: 477-87.
    • (1989) Cell , vol.59 , pp. 477-487
    • Tora, L.1    White, J.2    Brou, C.3
  • 6
    • 84995870933 scopus 로고
    • Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions
    • Tzukerman MT, Esty A, Santiso-Mere D, et al. Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol Endocrinol 1994; 8: 21-30.
    • (1994) Mol Endocrinol , vol.8 , pp. 21-30
    • Tzukerman, M.T.1    Esty, A.2    Santiso-Mere, D.3
  • 7
    • 0029058152 scopus 로고
    • The carboxyterminal F domain of the human estrogen receptor: Role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogens antagonists
    • Montano MM, Muller V, Trobaugh A, Katzenellenbogen BS. The carboxyterminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogens antagonists. Mol Endocrinol 1995; 9: 814-25.
    • (1995) Mol Endocrinol , vol.9 , pp. 814-825
    • Montano, M.M.1    Muller, V.2    Trobaugh, A.3    Katzenellenbogen, B.S.4
  • 8
    • 0028179150 scopus 로고
    • Estrogen receptor expression of benign breast epithelium and its association with breast cancer
    • Khan SA, Rogers M, Obando JA, Tamsen A. Estrogen receptor expression of benign breast epithelium and its association with breast cancer. Cancer Res 1994; 54: 993-7.
    • (1994) Cancer Res , vol.54 , pp. 993-997
    • Khan, S.A.1    Rogers, M.2    Obando, J.A.3    Tamsen, A.4
  • 9
    • 0029603610 scopus 로고
    • Multistep progression from an oestrogen dependent growth towards an autonomous growth in breast carcinogenesis
    • Schmitt FC. Multistep progression from an oestrogen dependent growth towards an autonomous growth in breast carcinogenesis. Eur J Cancer 1995; 12: 2049-52.
    • (1995) Eur J Cancer , vol.12 , pp. 2049-2052
    • Schmitt, F.C.1
  • 10
    • 0010512426 scopus 로고
    • Mechanisms associated with the progression of breast cancer from hormone dependence to independence
    • Murphy. LC. Mechanisms associated with the progression of breast cancer from hormone dependence to independence. Pezcoller Foundation J 1995; 6: 6-16.
    • (1995) Pezcoller Foundation J , vol.6 , pp. 6-16
    • Murphy, L.C.1
  • 11
    • 0025878197 scopus 로고
    • Identification of a dominant negative form of the estrogen receptor
    • Wang Y, Miksicek RJ. Identification of a dominant negative form of the estrogen receptor. Mol Endocrinol 1991; 5: 1707-15.
    • (1991) Mol Endocrinol , vol.5 , pp. 1707-1715
    • Wang, Y.1    Miksicek, R.J.2
  • 12
    • 0027394644 scopus 로고
    • Estrogen receptor variant messenger RNA lacking exon 4 in estrogen responsive human breast cancer cell lines
    • Pfeffer U, Fearotta E, Catagnetta L, Vidali G. Estrogen receptor variant messenger RNA lacking exon 4 in estrogen responsive human breast cancer cell lines. Cancer Res 1993; 53: 741-3.
    • (1993) Cancer Res , vol.53 , pp. 741-743
    • Pfeffer, U.1    Fearotta, E.2    Catagnetta, L.3    Vidali, G.4
  • 13
    • 0025967295 scopus 로고
    • Variant human breast tumor estrogen receptor with constitutive transcriptional activity
    • Fuqua SAW, Fitzgerald SD, Chamness GC, et al. Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res 1991; 51: 105-9.
    • (1991) Cancer Res , vol.51 , pp. 105-109
    • Fuqua, S.A.W.1    Fitzgerald, S.D.2    Chamness, G.C.3
  • 14
    • 0027219770 scopus 로고
    • Exon skipping gives rise to alternatively spliced forms of the estrogen receptor in breast tumor cells
    • Miksicek R, Lei Y, Wang Y. Exon skipping gives rise to alternatively spliced forms of the estrogen receptor in breast tumor cells. Breast Cancer Res Treat 1993; 26: 163-74.
    • (1993) Breast Cancer Res Treat , vol.26 , pp. 163-174
    • Miksicek, R.1    Lei, Y.2    Wang, Y.3
  • 15
    • 0026570643 scopus 로고
    • Inhibition of the estrogen receptor action by a naturally occurring variant in human breast tumors
    • Fuqua SAW, Fitzgerald SD, Allred DC, et al. Inhibition of the estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Res 1992; 52: 483-6.
    • (1992) Cancer Res , vol.52 , pp. 483-486
    • Fuqua, S.A.W.1    Fitzgerald, S.D.2    Allred, D.C.3
  • 16
    • 0029978698 scopus 로고    scopus 로고
    • Estrogen receptor variants in normal human mammary tissue
    • Leygue ER, Watson PH, Murphy LC. Estrogen receptor variants in normal human mammary tissue. J Natl Cancer Inst 1996; 88: 284-90.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 284-290
    • Leygue, E.R.1    Watson, P.H.2    Murphy, L.C.3
  • 17
    • 0029049398 scopus 로고
    • Human estrogen receptor messenger RNA variants in both normal and tumor tissues
    • Gotteland M, Desauty G, Delarue JC, Liu L, May E. Human estrogen receptor messenger RNA variants in both normal and tumor tissues. Mol Cell Endocrinol 1995; 112: 1-13.
    • (1995) Mol Cell Endocrinol , vol.112 , pp. 1-13
    • Gotteland, M.1    Desauty, G.2    Delarue, J.C.3    Liu, L.4    May, E.5
  • 18
    • 0029026592 scopus 로고
    • Coexpression of multiple estrogen receptor variant messenger RNAs in normal and neoplastic breast tissues and in MCF-7 cells
    • Pfeffer U, Fecarotta E, Vidali G. Coexpression of multiple estrogen receptor variant messenger RNAs in normal and neoplastic breast tissues and in MCF-7 cells. Cancer Res 1995; 55: 2158-65.
    • (1995) Cancer Res , vol.55 , pp. 2158-2165
    • Pfeffer, U.1    Fecarotta, E.2    Vidali, G.3
  • 20
    • 0029738763 scopus 로고    scopus 로고
    • Prevalence of estrogen receptor variant messenger RNAs in human breast cancer
    • Leygue E, Huang A, Murphy LC, Watson PH. Prevalence of estrogen receptor variant messenger RNAs in human breast cancer. Cancer Res 1996; 56: 4324-7.
    • (1996) Cancer Res , vol.56 , pp. 4324-4327
    • Leygue, E.1    Huang, A.2    Murphy, L.C.3    Watson, P.H.4
  • 21
    • 0025195407 scopus 로고
    • CO cells, genetically unstable and containing estrogen receptor mutations are a model for the progression of breast cancers to hormone resistance
    • CO cells, genetically unstable and containing estrogen receptor mutations are a model for the progression of breast cancers to hormone resistance. Cancer Res 1990; 50: 6208-17.
    • (1990) Cancer Res , vol.50 , pp. 6208-6217
    • Graham, M.L.1    Krett, N.L.2    Miller, L.A.3
  • 23
    • 0029613870 scopus 로고
    • Tissue-dependent expression of a novel splice variant of the human oestrogen receptor
    • Daffada A, Dowsett M. Tissue-dependent expression of a novel splice variant of the human oestrogen receptor. J Steroid Biochem Mol Biol 1995; 55: 413-21.
    • (1995) J Steroid Biochem Mol Biol , vol.55 , pp. 413-421
    • Daffada, A.1    Dowsett, M.2
  • 24
    • 0024550254 scopus 로고
    • Variant estrogen receptor mRNA species detected in human breast cancer biopsy samples
    • Murphy LC, Dotzlaw H. Variant estrogen receptor mRNA species detected in human breast cancer biopsy samples. Mol Endocrinol 1989; 3: 687-93.
    • (1989) Mol Endocrinol , vol.3 , pp. 687-693
    • Murphy, L.C.1    Dotzlaw, H.2
  • 25
    • 0026780789 scopus 로고
    • Characterization of estrogen receptor variant mRNAs from human breast cancers
    • Dotzlaw H, Alkhalaf M, Murphy LC. Characterization of estrogen receptor variant mRNAs from human breast cancers. Mol Endocrinol 1992; 6: 773-85.
    • (1992) Mol Endocrinol , vol.6 , pp. 773-785
    • Dotzlaw, H.1    Alkhalaf, M.2    Murphy, L.C.3
  • 26
    • 0029935334 scopus 로고    scopus 로고
    • Novel mutations in the estrogen receptor messenger RNA in human breast cancers
    • Murphy LC, Wang M, Courts A, Dotzlaw H. Novel mutations in the estrogen receptor messenger RNA in human breast cancers. J Clin Endocrinol Metab 1996; 81: 1420-7.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 1420-1427
    • Murphy, L.C.1    Wang, M.2    Courts, A.3    Dotzlaw, H.4
  • 27
    • 0029865898 scopus 로고    scopus 로고
    • A novel 80 KDa human estrogen receptor containing a duplication of exons 6 and 7
    • Pink JJ, Wu SQ, Wolf DM, Bilimoria MM, Jordan VC. A novel 80 KDa human estrogen receptor containing a duplication of exons 6 and 7. Nucleic Acids Res 1996; 24: 962-9.
    • (1996) Nucleic Acids Res , vol.24 , pp. 962-969
    • Pink, J.J.1    Wu, S.Q.2    Wolf, D.M.3    Bilimoria, M.M.4    Jordan, V.C.5
  • 28
    • 85036491433 scopus 로고    scopus 로고
    • A point mutation in the human estrogen receptor gene is associated with the expression of an abnormal estrogen receptor mRNA containing a 69 novel nucleotide insertion
    • in press
    • Wang M, Dotzlaw H, Fuqua SAW, Murphy LC. A point mutation in the human estrogen receptor gene is associated with the expression of an abnormal estrogen receptor mRNA containing a 69 novel nucleotide insertion. Breast Cancer Res Treat (in press).
    • Breast Cancer Res Treat
    • Wang, M.1    Dotzlaw, H.2    Fuqua, S.A.W.3    Murphy, L.C.4
  • 29
    • 0028934347 scopus 로고
    • Estrogen receptor gene analysis in estrogen positive and receptor negative primary breast cancer
    • Roodi N, Bailey R, Kao WY, et al. Estrogen receptor gene analysis in estrogen positive and receptor negative primary breast cancer. J Natl Cancer Inst 1995; 87: 446-51.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 446-451
    • Roodi, N.1    Bailey, R.2    Kao, W.Y.3
  • 30
    • 77957219449 scopus 로고
    • Identification of a variant form of the human estrogen receptor with an amino acid replacement
    • Garcia T, Sanchez M, Cox J, Ross J, Schachter B. Identification of a variant form of the human estrogen receptor with an amino acid replacement. Nucleic Acids Res 1989; 17: 8364.
    • (1989) Nucleic Acids Res , vol.17 , pp. 8364
    • Garcia, T.1    Sanchez, M.2    Cox, J.3    Ross, J.4    Schachter, B.5
  • 33
  • 34
    • 0028093565 scopus 로고
    • The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain
    • Wolf DM, Jordan VC. The estrogen receptor from a tamoxifen stimulated MCF-7 tumor variant contains a point mutation in the ligand binding domain. Breast Cancer Res Treat 1994; 31: 129-38.
    • (1994) Breast Cancer Res Treat , vol.31 , pp. 129-138
    • Wolf, D.M.1    Jordan, V.C.2
  • 35
    • 0029154750 scopus 로고
    • A naturally occurring estrogen receptor mutation results in increased estrogenicity of a tamoxifen analog
    • Catherine WH, Wolf DM, Jordan VC. A naturally occurring estrogen receptor mutation results in increased estrogenicity of a tamoxifen analog. Mol Endocrinol 1995; 9: 1053-63.
    • (1995) Mol Endocrinol , vol.9 , pp. 1053-1063
    • Catherine, W.H.1    Wolf, D.M.2    Jordan, V.C.3
  • 36
    • 0028143234 scopus 로고
    • Estrogen resistance caused by a mutation in the estrogen receptor gene in a man
    • Smith EP, Boyd J, Frank G, et al. Estrogen resistance caused by a mutation in the estrogen receptor gene in a man. N Engl J Med 1994; 331: 1056-61.
    • (1994) N Engl J Med , vol.331 , pp. 1056-1061
    • Smith, E.P.1    Boyd, J.2    Frank, G.3
  • 37
    • 0025762451 scopus 로고
    • Possible linkage of the estrogen receptor gene to breast cancer in a family with late-onset disease
    • Zuppan P, Hall JM, Lee MK, Ponglikitmongkol M, King MC. Possible linkage of the estrogen receptor gene to breast cancer in a family with late-onset disease. Am J Hum Genet 1991; 48: 1065-8.
    • (1991) Am J Hum Genet , vol.48 , pp. 1065-1068
    • Zuppan, P.1    Hall, J.M.2    Lee, M.K.3    Ponglikitmongkol, M.4    King, M.C.5
  • 38
    • 0027219768 scopus 로고
    • Investigation of the origin of variant, truncated estrogen receptor-like mRNAs identified in some human breast cancer biopsy samples
    • Murphy LC, Dotzlaw H, Hamerton J, Schwarz J. Investigation of the origin of variant, truncated estrogen receptor-like mRNAs identified in some human breast cancer biopsy samples. Breast Cancer Res Treat 1993; 26: 149-61.
    • (1993) Breast Cancer Res Treat , vol.26 , pp. 149-161
    • Murphy, L.C.1    Dotzlaw, H.2    Hamerton, J.3    Schwarz, J.4
  • 39
    • 0029921874 scopus 로고    scopus 로고
    • Triple primer PCR: A new way to quantify truncated mRNA expression
    • Leygue E, Murphy LC, Kuttenn F, Watson PH. Triple primer PCR: a new way to quantify truncated mRNA expression. Am J Pathol 1996; 148: 1097-103.
    • (1996) Am J Pathol , vol.148 , pp. 1097-1103
    • Leygue, E.1    Murphy, L.C.2    Kuttenn, F.3    Watson, P.H.4
  • 41
    • 0028908142 scopus 로고
    • Relationship of clone 4 estrogen receptor variant mRNA expression to some known prognostic variables in human breast cancer
    • Murphy LC, Hilsenbeck SG, Dotzlaw H, Fuqua SAW. Relationship of clone 4 estrogen receptor variant mRNA expression to some known prognostic variables in human breast cancer. Clin Cancer Res 1995; 1: 115-59.
    • (1995) Clin Cancer Res , vol.1 , pp. 115-159
    • Murphy, L.C.1    Hilsenbeck, S.G.2    Dotzlaw, H.3    Fuqua, S.A.W.4
  • 42
    • 0028795855 scopus 로고
    • Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer
    • Daffada A, Johnston S, Smith I, Detre S, King N, Dowsett M. Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer. Cancer Res 1995; 55: 288-93.
    • (1995) Cancer Res , vol.55 , pp. 288-293
    • Daffada, A.1    Johnston, S.2    Smith, I.3    Detre, S.4    King, N.5    Dowsett, M.6
  • 43
    • 0029923438 scopus 로고    scopus 로고
    • Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells
    • Rea D, Parker MG. Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells. Cancer Res 1996; 56: 1556-63.
    • (1996) Cancer Res , vol.56 , pp. 1556-1563
    • Rea, D.1    Parker, M.G.2
  • 44
    • 0027146672 scopus 로고
    • Expression of a consecutively active estrogen receptor variant in the estrogen receptor negative BT-20 human breast cancer cell line
    • Castles CG, Fuqua SAW, Klotz D, Hill SM. Expression of a consecutively active estrogen receptor variant in the estrogen receptor negative BT-20 human breast cancer cell line. Cancer Res 1993; 53: 5934-9.
    • (1993) Cancer Res , vol.53 , pp. 5934-5939
    • Castles, C.G.1    Fuqua, S.A.W.2    Klotz, D.3    Hill, S.M.4
  • 45
    • 0029041374 scopus 로고
    • An estrogen independent MCF-7 breast cancer cell line which contains a novel 80 kilodalton estrogen receptor related protein
    • Pink JJ, Jiang S, Fritsch M, Jordan VC. An estrogen independent MCF-7 breast cancer cell line which contains a novel 80 kilodalton estrogen receptor related protein. Cancer Res 1995; 55: 2583-90.
    • (1995) Cancer Res , vol.55 , pp. 2583-2590
    • Pink, J.J.1    Jiang, S.2    Fritsch, M.3    Jordan, V.C.4
  • 46
    • 0023802879 scopus 로고
    • Defective estrogen receptor in human mammary cancers: Their significance in defining hormone dependence
    • Raam S, Robert N, Pappas CA, Tamura H. Defective estrogen receptor in human mammary cancers: their significance in defining hormone dependence. J Natl Cancer Inst 1988; 80: 756-61.
    • (1988) J Natl Cancer Inst , vol.80 , pp. 756-761
    • Raam, S.1    Robert, N.2    Pappas, C.A.3    Tamura, H.4
  • 48
    • 0025678887 scopus 로고
    • Discrepancies between antibody (EIA) and saturation analysis of oestrogen receptor content in breast tumour samples
    • Marsigliante S, Puddefoot JR, Barker S, Gledhill J, Vinson GP. Discrepancies between antibody (EIA) and saturation analysis of oestrogen receptor content in breast tumour samples. J Steroid Biochem Molec Biol 1990; 37: 643-8.
    • (1990) J Steroid Biochem Molec Biol , vol.37 , pp. 643-648
    • Marsigliante, S.1    Puddefoot, J.R.2    Barker, S.3    Gledhill, J.4    Vinson, G.P.5
  • 49
    • 0025737917 scopus 로고
    • Truncated forms of DNA-binding estrogen receptors in human breast cancer
    • Scott GK, Kushner P, Vigne JL, Benz CC. Truncated forms of DNA-binding estrogen receptors in human breast cancer. J Clin Invest 1991; 88: 700-6.
    • (1991) J Clin Invest , vol.88 , pp. 700-706
    • Scott, G.K.1    Kushner, P.2    Vigne, J.L.3    Benz, C.C.4
  • 50
    • 0026408533 scopus 로고
    • Comparison of estrogen receptors in hormone dependent a hormone independent Grunder strain mouse mammary tumors
    • Moncharmont B, Ramp G, De Goeij C, Sluyser M. Comparison of estrogen receptors in hormone dependent a hormone independent Grunder strain mouse mammary tumors. Cancer Res 1991; 51: 3843-8.
    • (1991) Cancer Res , vol.51 , pp. 3843-3848
    • Moncharmont, B.1    Ramp, G.2    De Goeij, C.3    Sluyser, M.4
  • 52
    • 0029804489 scopus 로고    scopus 로고
    • Immunohistochemical assay for oestrogen receptors in paraffin wax sections of breast carcinoma using a new monoclonal antibody
    • Huang A, Pettigrew N, Watson PH. Immunohistochemical assay for oestrogen receptors in paraffin wax sections of breast carcinoma using a new monoclonal antibody. J Pathol 1997; 180: 223-7.
    • (1997) J Pathol , vol.180 , pp. 223-227
    • Huang, A.1    Pettigrew, N.2    Watson, P.H.3
  • 53
    • 85036487765 scopus 로고    scopus 로고
    • Expression of estrogen receptor variant mRNAs and determination of estrogen receptor status in human breast cancer
    • in press
    • Huang A, Leygue E, Snell L, Murphy LC, Watson PH. Expression of estrogen receptor variant mRNAs and determination of estrogen receptor status in human breast cancer. Am J Pathol (in press).
    • Am J Pathol
    • Huang, A.1    Leygue, E.2    Snell, L.3    Murphy, L.C.4    Watson, P.H.5
  • 54
    • 0029923438 scopus 로고    scopus 로고
    • Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells
    • Rea D, Parker MG. Effects of an exon 5 variant of the estrogen receptor in MCF-7 breast cancer cells. Cancer Res 1996; 56: 1556-63.
    • (1996) Cancer Res , vol.56 , pp. 1556-1563
    • Rea, D.1    Parker, M.G.2
  • 55
    • 0029061542 scopus 로고
    • Molecular aspects of estrogen receptor variants in breast cancer
    • Fuqua SAW, Wolf DM. Molecular aspects of estrogen receptor variants in breast cancer. Breast Cancer Res Treat 1995; 35: 233-41.
    • (1995) Breast Cancer Res Treat , vol.35 , pp. 233-241
    • Fuqua, S.A.W.1    Wolf, D.M.2
  • 56
    • 0027258030 scopus 로고
    • Peptide growth factors elicit estrogen receptor dependent transcription activation of an estrogen responsive element
    • Ignar-Trowbridge DM, Ten g CT, Ross KA, Parker MG, Korach KS, McLachlan JA. Peptide growth factors elicit estrogen receptor dependent transcription activation of an estrogen responsive element. Mol Endocrinol 1993; 7: 992-8.
    • (1993) Mol Endocrinol , vol.7 , pp. 992-998
    • Ignar-Trowbridge, D.M.1    Teng, C.T.2    Ross, K.A.3    Parker, M.G.4    Korach, K.S.5    McLachlan, J.A.6
  • 57
    • 0028997307 scopus 로고
    • HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells
    • Pietras RJ, Arboleda J, Reese DM, et al. HER-2 tyrosine kinase pathway targets estrogen receptor and promotes hormone-independent growth in human breast cancer cells. Oncogens 1995; 10: 2435-46.
    • (1995) Oncogens , vol.10 , pp. 2435-2446
    • Pietras, R.J.1    Arboleda, J.2    Reese, D.M.3
  • 58
    • 0029000596 scopus 로고
    • Differential expression of wild-type and variant estrogen receptor mRNAs by stocks of MCF-7 breast cancer cells may account for differences in estrogen responsiveness
    • Klotz DM, Castles CG, Fuqua SAW, Spriggs LL, Hill SM. Differential expression of wild-type and variant estrogen receptor mRNAs by stocks of MCF-7 breast cancer cells may account for differences in estrogen responsiveness. Biochem Biophys Res Commun 1995; 210: 609-14.
    • (1995) Biochem Biophys Res Commun , vol.210 , pp. 609-614
    • Klotz, D.M.1    Castles, C.G.2    Fuqua, S.A.W.3    Spriggs, L.L.4    Hill, S.M.5
  • 59
    • 0029974755 scopus 로고    scopus 로고
    • Estrogen receptor mRNA variants. Do they have a physiological role?
    • Pfeffer U. Estrogen receptor mRNA variants. Do they have a physiological role? Ann N Y Acad Sci 1996; 784: 304-13.
    • (1996) Ann N Y Acad Sci , vol.784 , pp. 304-313
    • Pfeffer, U.1
  • 60
    • 0027222739 scopus 로고
    • Wild-type and alternatively spliced estrogen receptor messenger RNA in human meningioma tissue and MCF-7 breast cancer cells
    • Koehorst SG, Jacobs HM, Thijssen JH, Blankenstein MA. Wild-type and alternatively spliced estrogen receptor messenger RNA in human meningioma tissue and MCF-7 breast cancer cells. J Steroid Biochem Mol Biol 1993; 45: 227-33.
    • (1993) J Steroid Biochem Mol Biol , vol.45 , pp. 227-233
    • Koehorst, S.G.1    Jacobs, H.M.2    Thijssen, J.H.3    Blankenstein, M.A.4
  • 61
    • 0029870305 scopus 로고    scopus 로고
    • Identification of a novel isoform of estrogen receptor, a potential inhibitor of estrogen action, in vascular smooth muscle cells
    • Inoue S, Hoshino S-J, Miyoshi M, et al. Identification of a novel isoform of estrogen receptor, a potential inhibitor of estrogen action, in vascular smooth muscle cells. Biochem Biophys Res Commun 1996; 219: 766-72.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 766-772
    • Inoue, S.1    Hoshino, S.-J.2    Miyoshi, M.3
  • 62
    • 0028314538 scopus 로고
    • Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue
    • Koehorst SGA, Cox JJ, Donker GH, et al. Functional analysis of an alternatively spliced estrogen receptor lacking exon 4 isolated from MCF-7 breast cancer cells and meningioma tissue. Mol Cell Endocrinol 1994; 101: 237-45.
    • (1994) Mol Cell Endocrinol , vol.101 , pp. 237-245
    • Koehorst, S.G.A.1    Cox, J.J.2    Donker, G.H.3
  • 63
    • 0027328914 scopus 로고
    • The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain
    • Fuqua SAW, Allred DC, Elledge RM, et al. The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain. Breast Cancer Res Treat 1993; 26: 191-202.
    • (1993) Breast Cancer Res Treat , vol.26 , pp. 191-202
    • Fuqua, S.A.W.1    Allred, D.C.2    Elledge, R.M.3
  • 64
    • 0022653964 scopus 로고
    • Human oestrogen receptor cDNA: Sequence, expression, and homology to v-erb-A
    • Green S, Walter P, Kumar V, et al. Human oestrogen receptor cDNA: sequence, expression, and homology to v-erb-A. Nature 1986; 320: 134-9.
    • (1986) Nature , vol.320 , pp. 134-139
    • Green, S.1    Walter, P.2    Kumar, V.3
  • 65
    • 0023740699 scopus 로고
    • A variant estrogen receptor messenger ribonucleic acid with reduced levels of estrogen binding in human mammary tumors
    • Garcia T, Lehrer S, Bloomer W, Schachter B. A variant estrogen receptor messenger ribonucleic acid with reduced levels of estrogen binding in human mammary tumors. Mol Endocrinol 1988; 2: 785-91.
    • (1988) Mol Endocrinol , vol.2 , pp. 785-791
    • Garcia, T.1    Lehrer, S.2    Bloomer, W.3    Schachter, B.4
  • 66
    • 0027270785 scopus 로고
    • An estrogen receptor genetic polymorphism and a history of spontaneous abortion - Correlation in women with estrogen receptor positive breast cancer but not in women with estrogen receptor negative breast cancer or in women without cancer
    • Lehrer SP, Schmutzler RK, Rabin JM, Schachter BS. An estrogen receptor genetic polymorphism and a history of spontaneous abortion - correlation in women with estrogen receptor positive breast cancer but not in women with estrogen receptor negative breast cancer or in women without cancer. Breast Cancer Res Treat 1993; 26: 175-80.
    • (1993) Breast Cancer Res Treat , vol.26 , pp. 175-180
    • Lehrer, S.P.1    Schmutzler, R.K.2    Rabin, J.M.3    Schachter, B.S.4
  • 67
    • 0028006795 scopus 로고
    • Association of an estrogen receptor variant with increased height in women
    • Lehrer S, Rabin J, Stone J, Berkowitz GS. Association of an estrogen receptor variant with increased height in women. Horm Metab Res 1994; 26: 486-8.
    • (1994) Horm Metab Res , vol.26 , pp. 486-488
    • Lehrer, S.1    Rabin, J.2    Stone, J.3    Berkowitz, G.S.4
  • 68
  • 69
    • 0024440781 scopus 로고
    • The cloned human estrogen receptor contains a mutation which alters its hormone binding properties
    • Tora L, Mullick A, Metzger D, Ponglikitmongkol M, Park I, Chambon P. The cloned human estrogen receptor contains a mutation which alters its hormone binding properties. EMBO J 1989; 8: 1981-6.
    • (1989) EMBO J , vol.8 , pp. 1981-1986
    • Tora, L.1    Mullick, A.2    Metzger, D.3    Ponglikitmongkol, M.4    Park, I.5    Chambon, P.6
  • 70
    • 0027074640 scopus 로고
    • Point mutation of the estrogen receptor (ER) in the ligand binding domain changes the pharmacology of antiestrogen in ER-negative breast cancer cells stably expressing complementary DNAs for ER
    • Jiang S-Y, Langan-Fahey S, Stella A, McCague R, Jordan VC. Point mutation of the estrogen receptor (ER) in the ligand binding domain changes the pharmacology of antiestrogen in ER-negative breast cancer cells stably expressing complementary DNAs for ER. Mol Endocrinol 1992; 6: 2167-74.
    • (1992) Mol Endocrinol , vol.6 , pp. 2167-2174
    • Jiang, S.-Y.1    Langan-Fahey, S.2    Stella, A.3    McCague, R.4    Jordan, V.C.5
  • 71
    • 0026751934 scopus 로고
    • Structural requirements for high affinity ligand binding by estrogen receptors: A comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast and mammalian cells
    • Wooge CH, Nilsson G, Heierson A, McDonnell D, Katzenellenbogen B. Structural requirements for high affinity ligand binding by estrogen receptors: a comparative analysis of truncated and full length estrogen receptors expressed in bacteria, yeast and mammalian cells. Mol Endocrinol 1992; 6: 861-9.
    • (1992) Mol Endocrinol , vol.6 , pp. 861-869
    • Wooge, C.H.1    Nilsson, G.2    Heierson, A.3    McDonnell, D.4    Katzenellenbogen, B.5
  • 72
    • 0026744710 scopus 로고
    • Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination
    • Pakdel F, Katzenellenbogen B. Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination. J Biol Chem 1992; 267: 3429-37.
    • (1992) J Biol Chem , vol.267 , pp. 3429-3437
    • Pakdel, F.1    Katzenellenbogen, B.2
  • 73
    • 0025329841 scopus 로고
    • Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor
    • Fawell SE, Lees JA, White R, Parker MG. Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor. Cell 1990; 60: 953-62.
    • (1990) Cell , vol.60 , pp. 953-962
    • Fawell, S.E.1    Lees, J.A.2    White, R.3    Parker, M.G.4
  • 74
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormone
    • Beato M. Gene regulation by steroid hormone. Cell 1989; 56: 335-44.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 75
    • 0024372113 scopus 로고
    • Mechanisms of nuclear localization of the progesterone receptor: Evidence for interaction of monomers
    • Guichon-Mantel A, Loosfelt H, Lescop P, et al. Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction of monomers. Cell 1989; 57: 1147-54.
    • (1989) Cell , vol.57 , pp. 1147-1154
    • Guichon-Mantel, A.1    Loosfelt, H.2    Lescop, P.3
  • 76
    • 0026552820 scopus 로고
    • Funcational analysis of a mutant estrogen receptor isolated from T47Dco breast cancer cells
    • Leslie KK, Tasset D, Horwitz KB. Funcational analysis of a mutant estrogen receptor isolated from T47Dco breast cancer cells. Am J Obstet Gynecol 1992; 166: 1053-61.
    • (1992) Am J Obstet Gynecol , vol.166 , pp. 1053-1061
    • Leslie, K.K.1    Tasset, D.2    Horwitz, K.B.3
  • 77
    • 0029841146 scopus 로고    scopus 로고
    • Identification of an estrogen response element activated by metabolites of 17b-estradiol and raloxifene
    • Yang NN, Venugopalan M, Hardikar S, Galsebrook A. Identification of an estrogen response element activated by metabolites of 17b-estradiol and raloxifene. Science 1996; 273: 1222-5.
    • (1996) Science , vol.273 , pp. 1222-1225
    • Yang, N.N.1    Venugopalan, M.2    Hardikar, S.3    Galsebrook, A.4
  • 78
    • 0025695290 scopus 로고
    • Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex
    • Gaub MP, Bellard M, Scheure I, Chambon R Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell 1990; 63: 1267-76.
    • (1990) Cell , vol.63 , pp. 1267-1276
    • Gaub, M.P.1    Bellard, M.2    Scheure, I.3    Chambon, R.4
  • 79
    • 0028287546 scopus 로고
    • Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells
    • Krishnan V, Wang X, Safe S. Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells. J Biol Chem 1994; 269: 15912-7.
    • (1994) J Biol Chem , vol.269 , pp. 15912-15917
    • Krishnan, V.1    Wang, X.2    Safe, S.3
  • 80
    • 0027973035 scopus 로고
    • A novel, cell-type-specific mechanism for estrogen receptor-mediated gene activation in the absence of an estrogen-responsive element
    • Sukovich DA, Mukherjee R, Benfield PA. A novel, cell-type-specific mechanism for estrogen receptor-mediated gene activation in the absence of an estrogen-responsive element. Mol Cell Biol 1994; 14: 7134-43.
    • (1994) Mol Cell Biol , vol.14 , pp. 7134-7143
    • Sukovich, D.A.1    Mukherjee, R.2    Benfield, P.A.3
  • 81
    • 0030593681 scopus 로고    scopus 로고
    • ERb: Identification and characterization of a novel human estrogen receptor
    • Mosselman S, Polman J, Dijkema R. ERb: identification and characterization of a novel human estrogen receptor. FEBS Lett 1996; 392: 49-53.
    • (1996) FEBS Lett , vol.392 , pp. 49-53
    • Mosselman, S.1    Polman, J.2    Dijkema, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.