The C-terminal part of VIP is important for receptor binding and activation, as evidenced by chimeric constructs of VIP/secretin

FEBS Letters

Volumn 413, Issue 3, 1997, Pages 405-408

  Wulff, Birgitte ^a   Knudsen, Sanne Møller ^b   Adelhorst, Kim ^a   Fahrenkrug, Jan ^b  

^a NOVO NORDISK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Chimera; Receptor binding; Secretin; Vasoactive intestinal polypeptide

Indexed keywords

CHIMERIC PROTEIN; CYCLIC AMP; SECRETIN; SECRETIN DERIVATIVE; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE DERIVATIVE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL LINE; CHO CELL; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GENE CONSTRUCT; GENE EXPRESSION; GENE TRANSFER; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION;

1-METHYL-3-ISOBUTYLXANTHINE; ADENYLATE CYCLASE; AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CHO CELLS; CRICETINAE; CYCLIC AMP; ENZYME ACTIVATION; KINETICS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RATS; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL POLYPEPTIDE, TYPE I; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SECRETIN; TRANSFECTION; VASOACTIVE INTESTINAL PEPTIDE;

ANIMALIA;

EID: 0030801196     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00942-3     Document Type: Article

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