Delayed chronic diarrhea and weight loss possibly due to ticlopidine therapy

Annals of Pharmacotherapy

Volumn 31, Issue 7-8, 1997, Pages 870-872

  Mansoor, George A ^a,b,c   Aziz, Khalid ^a,b  

^a UNIVERSITY OF CONNECTICUT SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Diarrhea; Ticlopidine; Weight loss

Indexed keywords

ATENOLOL; FELODIPINE; FLUINDOSTATIN; HYDROCHLOROTHIAZIDE; ISOSORBIDE DINITRATE; LISINOPRIL; TICLOPIDINE;

ADULT; AGRANULOCYTOSIS; ANOREXIA; ARTICLE; CASE REPORT; CHRONIC DIARRHEA; CLINICAL FEATURE; DYSPEPSIA; HUMAN; MALE; NAUSEA; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RASH; WEIGHT REDUCTION;

EID: 0030800270     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1177/106002809703100713     Document Type: Article

References (15)

1. Hass WK, Easton JD, Adams HP, Pryse-Phillips W, Molony BA, Anderson S, et al. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high risk patients. N Engl J Med 1989;321:501-7.
2. Gent M, Blakely JA, Easton JD, Ellis DJ, Hachinski VC, Harbison JW, et al. The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Lancet 1989;1:1215-20.
3. Ito MK, Smith AR, Lee ML. Ticlopidine: a new platelet aggregation inhibitor. Clin Pharm 1992;11:603-17.
4. Barnett HJM, Eliasziw M, Meldrum HE. Drugs and surgery in the prevention of ischemic stroke. N Engl J Med 1995;332:238-48.
5. Haynes RB, Sandler RS, Larson EB, Pater JL, Yatsu FM. A critical appraisal of ticlopidine, a new antiplatelet agent. Arch Intern Med 1992; 152:1376-80.
6. Ruget O, Burtin P, Cerez H, Cales P, Boyer J. Chronic diarrhea associated with villous atrophy and lymphocytic gastritis caused by ticlopidine. Gastroenterol Clin Biol 1992;16:290.
7. Rota Roca MR, Castellote J, Xiol X, Sanchez Gili M. Severe chronic diarrhea caused by ticlopidine. Med Clin (Barc) 1992;98:397-8.
8. Valdes Oliveras M, Barenys de Lacha M, Abad Lacruz A, Admetlla Falgueras M. Chronic diarrhea caused by ticlopidine. An Med Interna 1993;10:520.
9. Diaz Morant V, Molina Ruano FJ, Manteca Gonzales R, Canamero Peral D, Miramon Lopez J. Chronic diarrhea and ticlopidine. Gastroenterol Hepatol 1995;18:354-5.
10. Hoffman HS, Butensky MS. Severe diarrhea with Ticlid therapy. Conn Med 1994;58:251.
11. Chassany O, Bacq Y, Metman EH, Gillion JM, Dorval ED, Jankowski JM. Severe chronic diarrhea after treatment with ticlopidine. Gastroenterol Clin Biol 1989;13:950.
12. Giardina MG, Matarazzo M, Cacciatore L, De Marco F. Ticlopidine can cause chronic diarrhea. Lancet 1984;1:407.
13. Guedon C, Bruna T, Ducrotte P, Lerebours E, Denis P, Colin R. Severe diarrhea caused by Ticlid associated with disorders of small bowel motility. Gastroenterol Clin Biol 1989;13:934-7.
14. Desager JP. Clinical pharmacokinetics of ticlopidine. Clin Pharmacokinet 1994;26:347-55.
15. Rachmilewitz D. Prostaglandins and diarrhea. Dig Dis Sci 1980;25:897-8.