Trans-rearrangements and the risk of lymphoid malignancy

Annals of Oncology

Volumn 8, Issue SUPPL. 2, 1997, Pages

  Kirsch, I R ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biomarkers; Genetic instability; Lymphomagenesis; Trans rearrangements; V(D)J recombination

Indexed keywords

BIOLOGICAL MARKER; BLEOMYCIN; CYCLOPHOSPHAMIDE; DACARBAZINE; DNA; DOXORUBICIN; ETOPOSIDE; GENE PRODUCT; IMMUNOGLOBULIN; LYMPHOCYTE ANTIGEN RECEPTOR; PESTICIDE; PHOSPHOTRANSFERASE; PREDNISONE; PROTEIN KINASE; T LYMPHOCYTE RECEPTOR; VINBLASTINE; VINCRISTINE;

AGRICULTURAL WORKER; ANIMAL MODEL; ATAXIA TELANGIECTASIA; CHROMOSOME INVERSION; CHROMOSOME TRANSLOCATION; CONFERENCE PAPER; CYTOGENETICS; DNA DAMAGE; EXPOSURE; GENE; GENE REARRANGEMENT; GENETIC PREDISPOSITION; GENETIC STABILITY; HODGKIN DISEASE; HUMAN; KARYOTYPE; LYMPHOMA; MOUSE; NONHUMAN; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK; SOUTHERN BLOTTING;

EID: 0030800094     PISSN: 09237534     EISSN: None     Source Type: Journal    
DOI: 10.1093/annonc/8.suppl_2.S45     Document Type: Conference Paper

References (37)

1. Kirsch IR, Kuehl WM. Gene rearrangements in lymphoid cells. In Stamatoyannopoulos G (ed): The Molecular Basis of Blood Diseases. Philadelphia: W.B. Saunders 1993
2. Baer R, Chen KC, Smith SD et al. Fusion of an immunoglobulin variable gene and a T-cell receptor constant gene in the chromosome 14 inversion associated with T-cell tumors. Cell 1985; 43: 705-13.
3. Denny CT, Yoshikai Y, Mak T et al. A chromosomal inversion in a T cell lymphoma is caused by site-specific recombination between immunoglobulin and T cell receptor loci. Nature 1986; 320: 549-51.
4. Tycko B, Palmer JD, Sklar J. T-cell receptor gene trans-rearrangements: Chimeric γδ genes in normal lymphoid tissues. Science 1989; 245: 1242-6.
5. Stern M-H, Lipkowitz S, Aurias A et al. Inversion of chromosome 7 in ataxia telangiectasia is generated by a rearrangement between T-cell receptor beta and T-cell receptor gamma genes. Blood 1989; 74: 2076-80.
6. Lipkowitz S, Stern MH, Kirsch IR. Hybrid T cell receptor genes formed by interlocus recombination in normal and ataxia-telangiectasia lymphocytes. J Exp Med 1990; 172: 409-18.
7. Kobayashi Y, Tycko B, Soreng AL et al. Transrearrangements between antigen receptor genes in normal human lymphoid tissues and in ataxia telangiectasia. J Immunol 1991; 147: 3201-9.
8. Aurias A, Couturier J, Dutrillaux AM et al. Inversion (14)(q12qter) or (q11.2q32.3): The most frequently acquired rearrangement in lymphocytes. Hum Genet 1985; 71: 19-21.
9. Aurias A. Acquired chromosomal aberrations in normal individuals. In Kirsch IR (ed): The Causes and Consequences of Chromosomal Aberrations. Boca Raton, FL: CRC Press 1993; 125-39.
10. Hecht F, Hecht BK, Kirsch IR. Fragile sites limited to lymphocytes: Molecular recombination and malignancy. Cancer Genet Cytogenet 1987; 26: 95-104.
11. Boder E. Ataxia-telangiectasia: An overview. In Gatti RA, Swift M (eds): Ataxia-telangiectasia: Genetics, Neuropathology, and Immunology of a Degenerative Disease of Childhood. New York: Alan R. Liss 1985; 1-63.
12. Stern M-H. Clonal T-cell proliferations in ataxia telangiectasia. In Kirsch IR (ed): The Causes and Consequences of Chromosomal Aberrations. Boca Raton, FL: CRC Press 1993; 165-76.
13. Hunter T. When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell 1995; 83: 1-4.
14. Weisenburger DD. Epidemiology of non-Hodgkin's lymphoma: Recent findings regarding an emerging epidemic. Ann Oncol 1994; 5 (Suppl 1): S19-24.
15. Lipkowitz S, Garry VF, Kirsch IR. Interlocus V-J recombination measures genomic instability in agriculture workers at risk for lymphoid malignancies. Proc Natl Acad Sci USA 1992; 89: 5301-5.
16. Tucker MA, Coleman CN, Cox RS et al. Risk of second cancers after treatment for Hodgkin's disease. N Engl J Med 1988; 318: 76-81.
17. Van Leeuwen FE, Klokman WJ, Hagenbeek A, et al. Second cancer risk following Hodgkin's disease: A 20-year follow-up study J Clin Oncol 1994; 12: 312-25.
18. Abdallah JM, Lombardi DP, Kirsch IR. Genetic instability in patients with Hodgkin's disease undegoing chemotherapy. J Clin Invest 1995; 96: 2744-7.
19. Fishbein WN, Foellmer JW, Davis JI et al. Detection of very-rarecopy DNA in 0.2-ml dried human blood blots. Biochem Mol Med 1995; 56: 152-7.
20. Kaplan HS, Brown MB. A quantitative dose-response study of lymphoid-tumor development in irradiated C57 black mice. J Natl Cancer Inst 1952; 13: 185-208.
21. Kaplan HS. Natural history of the murine leukemias: Presidential address. Cancer Res 1967; 27: 1325-40.
22. Danska JS, Pflumio F, Williams CJ et al. Rescue of T cell-specific V(D)J recombination in SCID mice by DNA-damaging agents. Science 1994; 266: 450-5.
23. Mallick C, Dudley E, Viney J et al. Rearrangement and diversity of T cell receptor beta chain genes in thymocytes: A critical role for the beta chain in development. Cell 1993; 73: 513-9.
24. Dudley E, Petrie H, Shah L et al. T cell receptor beta chain gene rearrangement and selection during thymocyte development in adult mice. Immunity 1994; 1: 83-93.
25. Blunt T, Finnie NJ, Taccioli GE et al. Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation. Cell 1995; 80 (5): 813-23.
26. Kirchgessner CU, Patil CK, Evans JW et al. DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect. Science 1995; 267 (5201): 1178-83.
27. Tycko B, Coyle H, Sklar J. Chimeric γ-δ signal joints: Implications for the mechanism and regulation of T cell receptor gene rearrangement. J Immunol 1991; 147: 705-13.
28. Yancopoulos GD, Alt FW. Developmentally controlled and tissue-specific expression of unrearranged VH gene segments. Cell 1985; 40: 271-81.
29. Blackwell TK, Moore MW, Yancopoulos GD et al. Recombination between immunoglobulin variable region gene segments is enhanced by transcription. Nature 1986; 324: 585-9.
30. Kirsch IR, Brown JA, Lawrence J et al. Translocations that highlight chromosomal regions of differentiated activity. Cancer Genet Cytogenet 1985; 18: 159-72.
31. Boehm T, Mengle-Gaw L, Kees UR et al. Alternating purine-pyrimidine tracts may promote chomosomal translocation seen in a variety of human lymphoid tumors. EMBO J 1989; 8: 2621-31.
32. Bolognesi C, Parrini M, Reggiardo G et al. Biomonitoring of workers exposed to pesticides. Int Arch Occup Environ Health 1993; 65 (Suppl. 1) S185-7.
33. Caggana M, Liber HL, Mauch PM et al. In vivo somatic mutation in the lymphocytes of Hodgkin's disease patients. Environ Mol Mutagen 1991; 18: 6-13.
34. Caggana M, Liber HL, Coleman CN et al. A prospective study of hprt mutant and mutation frequencies in treated cancer patients. Cancer Epid Biomark Prev 1992; 1: 573-80.
35. Mott MG, Boyse J, Hewitt M et al. Do mutations at the glycophorin A locus in patients treated for childhood Hodgkin's disease predict secondary leukaemia? Lancet 1994; 343: 828-9.
36. Jensen RH, Langlois RG, Bigbee WL et al. Elevated frequency of glycophorin A mutations in erythrocytes from Chernobyl accident victims. Radiat Res 1995; 141 (2): 129-35.
37. Lieber MR. The role of site-directed recombinases in physiologic and pathologic chromosomal rearrangements. In Kirsch IR (ed): The Causes and Consequences of Chromosomal Aberrations. Boca Raton. FL: CRC Press 1993; 239-75.