Quaternary structure-dependent idiotope and antigen binding of a monoclonal antibody specific for conformational epitope on type II collagen

Cellular and Molecular Life Sciences

Volumn 53, Issue 1, 1997, Pages 51-60

  Ito, H O ^a   Ueda, T ^a   Hashimoto, Y ^a   Imoto, T ^a   Koga, T ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Anti idiotypic antibody; Autoimmune arthritis; Higher order structure; Protein protein interaction; Type II collagen

Indexed keywords

COLLAGEN TYPE 3; EPITOPE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; ANTIBODY SPECIFICITY; ANTIBODY STRUCTURE; ANTIGEN BINDING; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; PROTEIN PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; COLLAGEN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MICE, INBRED DBA; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN DENATURATION; RECOMBINANT FUSION PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030799765     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000579     Document Type: Article

References (36)

1. Stuart J. M., Townes A. S. and Kang A. H. (1982) Nature and specificity of the immune response to collagen in type II collagen-induced arthritis in mice. J. Clin. Invest. 69: 673-683
2. Holmdahl R., Jansson L., Gullberg D., Rubin K., Forsberg P. O. and Klareskog L. (1985) Incidence of arthritis and autoreactivity of anti-collagen antibodies after immunization of DBA 1 mice with heterologous and autologous collagen II. Clin. Exp. Immunol. 62: 639-646
3. Terato K., Hasty K. A., Reife R. A., Cremer M. A., Kang A. H. and Stuart J. M. (1992) Induction of arthritis with monoclonal antibodies to collagen. J. Immunol. 148: 2103-2108
4. Iribe H., Kabashima H., Kakimoto K. and Koga T. (1988) Induction of an anti-human type II collagen response by monoclonal anti-idiotypic antibody. J. Immunol. 140: 4151-4156
5. Iribe H., Kabashima H., Ishii Y. and Koga I. (1988) Epitope specificity of antibody response against human type II collagen in the mouse susceptible to collagen-induced arthritis and patients with rheumatoid arthritis. Clin. Exp. Immunol. 73: 443-448
6. Iribe H., Kabashima H. and Koga T. (1989) Antibody response against a possible arthritogenic epitope on human type II collagen induced by anti-idiotypic antibody. J. Immunol. 142: 1487-94
7. Tarutani S. (1993) Collagen-induced arthritis suppressed with monoclonal anti-idiotypic antibody. Microbiol. Immunol. 37: 135-142
8. Köhler H., Muller S. and Bona C. (1985) Internal antigen and immune network. Proc. Soc. Exp. Biol. Med. 178: 189-195
9. Greenspan N. S. and Bona C. A. (1993) Idiotypes: structure and immunogenicity. FASEB. J. 7: 437-444
10. Nisonoff A. (1991) Idiotypes: concepts and applications. J. Immunol. 147: 2429-2438
11. Kakimoto K., Hirofuji T. and Koga T. (1984) Specificity of anti-type II collagen antibody response in rats. Clin. Exp. Immunol. 57: 57-62
12. Maeda Y., Koga H., Yamada H., Ueda T. and Imoto T. (1995) Effective renaturation of reduced lysozyme by gentle removal of urea. Protein Engineering 8: 201-205
13. Hoogenboom H. R., Marks J. D., Griffiths A. D. and Winter G. (1992) Building antibodies from their genes. Immunol. Rev. 130: 41-68
14. Kabat E. A., Wu T. T., Perry M., Gottesman K. S. and Foeller C. (1991) Sequences of Proteins of Immunological Interest. U.S. Dept. of Health and Human Services, Bethesda, MD
15. Blake M. S., Johnston K. H., Russell J. G. and Gotschlich E. C. (1984) A rapid, sensitive method for detection of alkaline phosphatase-conjugated anti-antibody on Western blots. Anal. Biochem. 136: 175-179
16. Umeda M., Diego I., Ball E. D. and Marcus D. M. (1986) Idiotypic determinants of monoclonal antibodies that bind to 3-fucosyllactosamine. J. Immunol. 136: 2562-2567
17. Sugiyama T., Imai K., Ono A., Takayama Y., Tsujisaki M., Taki T. et al. (1991) Conformational structure of a monoclonal anti-idiotypic antibody to the monoclonal anti-adenocarcinoma-associated carbohydrate antibody YH206. J. Immunol. 146: 3097-3101
18. Wang B. S., Zhang R. J., Bona C. A. and Moran T. M. (1994) Promotion of animal growth with a monoclonal anti-idiotype specific to anti-porcine growth hormone antibody. Mol. Immunol. 31: 651-656
19. Hall B. L., Zaghouani H., Daian C. and Bona C. A. (1992) A single amino acid mutation in CDR3 of the 3-14-9 L chain abolished expression of the IDA 10-defined idiotope and antigen binding. J. Immunol. 149: 1605-1612
20. Davis S. J. (1993) in reply to letter from Erlanger, B. F. et al. Nature 361: 212
21. Davis S. J., Schockmel G. A., Somoza C., Buck D. W., Healey D. G., Rieber E. P. et al. (1992) Antibody and HIV-1 gp120 recognition of CD4 undermines the concept of mimicry between antibodies and receptors. Nature 358: 76-79
22. Bruck C., Co M. S., Slaoui M., Gaulton G. N., Smith T., Fields B. N. et al. (1986) Nucleic acid sequence of an internal image-bearing monoclonal anti-idiotype and its comparison to the sequence of the external antigen. Proc. Natl. Acad. Sci. USA 83: 6578-6582
23. Saragovi H. U., Fitzpatrick D., Raktabutr A., Nakanishi H., Kahn M. and Greene M. I. (1991) Design and synthesis of a mimetic from an antibody complementarity-determining region. Science 253: 792-795
24. Williams W. V., Kieber E. T., Weiner D. B., Rubin D. H. and Greene M. I. (1991) Contact residues and predicted structure of the reovirus type 3-receptor interaction. J. Biol. Chem. 266: 9241-9250
25. Kodandapani R., Veerapandian B., Kunicki T. J. and Ely K. R. (1995) Crystal structure of the OPG2 Fab: an antireceptor antibody that mimics an RGD cell adhesion site. J. Biol. Chem. 270: 2268-2273
26. van Cleave V. H., Naeve C. W. and Metzger D. W. (1988) Do antibodies recognize amino acid side chains of protein antigens independently of the carbon backbone? J. Exp. Med. 167: 1841-1848
27. Billetta R., Hollingdale M. R. and Zanetti M. (1991) Immunogenicity of an engineered internal image antibody. Proc. Natl. Acad. Sci. USA 88: 4713-4717
28. Ban N., Escobar C., Garcia R., Hasel K., Day J., Greenwood A. et al. (1994) Crystal structure of an idiotype-anti-idiotype Fab complex. Proc. Natl. Acad. Sci. USA 91: 1604-1608
29. Bentley G. A., Boulot G., Riottot M. M. and Poljak R. J. (1990) Three-dimensional structure of an idiotope-anti-idiotope complex. Nature 348: 254-257
30. Colman P. M., Laver W. G., Varghese J. N., Baker A. T., Tulloch P. A., Air G. M. et al. (1987) Three-dimensional structure of a complex of antibody with influenza virus neuraminidase. Nature 326: 358-363
31. Fields B. A., Goldbaum F. A., Ysern X., Poljak R. J. and Mariuzza R. A. (1995) Molecular basis of antigen mimicry by an anti-idiotope. Nature 374: 739-742
32. Brodeur P. H. and Riblet R. (1984) The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes. Eur. J. Immunol. 14: 922-930
33. Strohal R., Helmberg A., Kroemer G. and Kofler R. (1989) Mouse Vk gene classification by nucleic acid sequence similarity. Immunogenetics 30: 475-493
34. Mo J. A., Bona C. A. and Holmdahl R. (1993) Variable region gene selection of immunoglobulin G-expressing B cells with specificity for a defined epitope on type II collagen. Eur. J. Immunol. 23: 2503-2510
35. Tillman D. M., Jou N. T., Hill R. J. and Marion T. N. (1992) Both IgM and IgG anti-DNA antibodies are the products of clonally selective B cell stimulation in (NZB x NZW)F1 mice. J. Exp. Med. 176: 761-779
36. Vandevyver C., Steukers M., Lambrechts J., Heyligen H. and Raus J. (1993) Development and functional characterization of a murine human chimeric antibody with specificity for the human interleukin-2 receptor. Mol. Immunol. 30: 865-876