Inhibition of inducible nitric oxide synthase expression by endothelin in rat glial cells prepared from the neonatal rat brain

Journal of Neurochemistry

Volumn 69, Issue 2, 1997, Pages 669-674

  Oda, Haruko ^a   Murayama, Toshihiko ^a   Nomura, Yasuyuki ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cyclic AMP; Endothelin; Endothelin B receptor; Inducible nitric oxide synthase; Rat glial cells

Indexed keywords

CYCLIC AMP; ENDOTHELIN; ENDOTHELIN B RECEPTOR; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; NITRIC OXIDE SYNTHASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GLIA CELL; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANIMALIA;

EID: 0030799551     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1997.69020669.x     Document Type: Article

References (29)

1. Aramori I. and Nakanishi S. (1992) Coupling of two endothelin receptor subtypes to differing signal transduction in transfected Chinese hamster ovary cells. J. Biol. Chem. 267, 12468-12474.
2. Boje K. M. and Arora P. K. (1992) Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 587, 250-256.
3. Bredt D. S. and Snyder S. H. (1994) Nitric oxide: a physiologic messenger molecule. Annu. Rev. Biochem. 63, 175-195.
4. Chandler L. J., Kopnisky K., Richards E., Crews F. T., and Sumners C. (1995) Angiotensin II decreases inducible nitric oxide synthase expression in rat astroglial cultures. Am. J. Physiol. 268, C700-C707.
5. Chao C. C., Hu S., Molitor T. W., Shaskan E. G., and Peterson P. K. (1992) Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J. Immunol. 149, 2736-2741.
6. Endoh M., Maiese K., and Wagner J. (1994) Expression of the inducible form of nitric oxide synthase by reactive astrocytes after transient global ischemia. Brain Res. 651, 92-100.
7. Feinstein D. L., Galea E., and Reis D. J. (1993) Norepinephrine suppresses inducible nitric oxide synthase activity in rat astroglial cultures. J. Neurochem. 60, 1945-1948.
8. 15N] nitrate in biological fluids. Anal. Biochem. 126, 131-138.
9. B receptor. Biochem. Biophys. Res. Commun. 186, 355-362.
10. Honma M., Satoh T., Takezawa J., and Ui M. (1977) An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue. Biochem. Med. 18, 257-273.
11. Iadecola C., Zhang F., Xu S., Casey R., and Ross E. (1995) Inducible nitric oxide synthase gene expression in brain following cerebral ischemia. J. Cereb. Blood Flow Metab. 15, 378-384.
12. A receptor. Life Sci. 50, 247-255.
13. Ishikawa K., Ihara M., Noguchi K., Mase T., Mino N., Saeki T., Fukuroda T., Fukami T., Ozaki S., Nagase T., Nishikabe M., and Yano M. (1994) Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ788. Proc. Natl. Acad. Sci. USA 91, 4892-4896.
14. 2+-insensitive but calmodulin-coupling nitric oxide synthase in rat glial cells. J. Neurosci. Res. 43, 235-245.
15. Koyama Y., Ishibashi T., Hayata K., and Baba A. (1993) Endothelins modulate dibutyryl cAMP-induced stellation of cultured astrocytes. Brain Res. 600, 81-88.
16. Nakayama I., Kawahara Y., Tsuda T., Okuda M., and Yokoyama M. (1994) Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells. J. Biol. Chem. 269, 11628-11633.
17. Nishiya T., Uehara T., and Nomura Y. (1995) Herbimycin A suppresses NF-κB activation and tyrosine phosphorylation of JAK2 and the subsequent induction of nitric oxide synthase in C6 glioma cells. FEBS Lett. 371, 333-336.
18. Nomura Y. and Kitamura Y. (1993) Inducible nitric oxide synthase in glial cells. Neurosci. Res. 18, 103-107.
19. Palmer R. M. J., Ferrige A. G., and Moncada S. (1987) Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327, 524-526.
20. Patel T. R. (1996) Therapeutic potential of endothelin receptor antagonists in cerebrovascular disease. CNS Drugs 5, 293-310.
21. Sakurai T., Yanagisawa M., and Masaki T. (1992) Molecular characterization of endothelin receptors. Trends Pharmacol. Sci. 13, 103-108.
22. Simmons M. L. and Murphy S. (1992) Induction of nitric oxide synthase in glial cells. J. Neurochem. 59, 897-905.
23. Sokolovsky M. (1995) Endothelin receptor heterogeneity, G-proteins, and signaling via cAMP and cGMP cascades. Cell. Mol. Neurobiol. 15, 561-571.
24. Takagi Y., Ninomiya H., Sakamoto A., Miwa S., and Masaki T. (1995) Structural basis of G protein specificity of human endothelin receptors. J. Biol. Chem. 270, 10072-10078.
25. B receptor. Biochem. Biophys. Res. Commun. 184, 953-959.
26. Takigawa M., Sakurai T., Kasuya Y., Abe Y., Masaki T., and Goto K. (1995) Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors. Eur. J. Biochem. 228, 102-108.
27. Yamashita K., Niwa M., Kataoka Y., Shigematsu K., Himeno A., Tsutsumi K., Nakano-Nakashima M., Sakurai-Yamashita Y., Shibata S., and Taniyama K. (1994) Microglia with an endothelin ETB receptor aggregate in rat hippocampus CA1 subfields following transient forebrain ischemia. J. Neurochem. 63, 1042-1051.
28. Yanagisawa M. and Masaki T. (1989) Molecular biology and biochemistry of the endothelins. Trends Pharmacol Sci. 10, 374-378.
29. Zhang F., Xu S., and Iadecola C. (1995) Time dependence of effect of nitric oxide synthase inhibition on cerebral ischemic damage. J. Cereb. Blood Flow Metab. 15, 595-601.