메뉴 건너뛰기




Volumn 14, Issue 4, 1997, Pages 257-267

Aerosols for administration of systemic drugs;VOIE INHALEE POUR L'ADMINISTRATION DE MEDICAMENTS A VISEE SYSTEMIQUE

Author keywords

Aerosols; Respiratory epithelium; Systemic treatments

Indexed keywords

AMILORIDE; CALCITONIN; CYCLOSPORIN; FUROSEMIDE; GONADORELIN; GROWTH HORMONE; HEPARIN; INSULIN; INTERFERON; MORPHINE; NICOTINE; PROSTACYCLIN; ANTICOAGULANT AGENT; ANTIDIABETIC AGENT; ANTIHYPERTENSIVE AGENT; ANTIVIRUS AGENT; CYCLOSPORIN DERIVATIVE; DIURETIC AGENT; DRUG; IMMUNOSUPPRESSIVE AGENT; NARCOTIC ANALGESIC AGENT; NICOTINIC AGENT;

EID: 0030799025     PISSN: 07618425     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (13)

References (112)
  • 1
    • 0026572056 scopus 로고
    • Pulmonary delivery of peptides and proteins for systemic action
    • PATTON JS, PLATZ RM : Pulmonary delivery of peptides and proteins for systemic action. Adv Drug Del Rev 1992;8: 179-96.
    • (1992) Adv Drug del Rev , vol.8 , pp. 179-196
    • Patton, J.S.1    Platz, R.M.2
  • 2
    • 0025282127 scopus 로고
    • Aerosols for systemic treatment
    • KÖHLER D : Aerosols for systemic treatment. Lung 1990;suppl:677-84.
    • (1990) Lung , vol.SUPPL , pp. 677-684
    • Köhler, D.1
  • 4
    • 0016377265 scopus 로고
    • Aerosol characterization and deposition
    • MORROW PE : Aerosol characterization and deposition. Am Rev Respir Dis 1974;110:88-9.
    • (1974) Am Rev Respir Dis , vol.110 , pp. 88-89
    • Morrow, P.E.1
  • 5
    • 0002277185 scopus 로고
    • Systemic therapy with aerosols. Aerosols in medecine
    • Moren F, Dolovich MB, Newhouse MT, Newman SP, eds. Elsevier Science Publishers BV
    • KÖHLER D : Systemic therapy with aerosols. Aerosols in medecine. In : Principles, diagnosis and therapy. Moren F, Dolovich MB, Newhouse MT, Newman SP, eds. Elsevier Science Publishers BV, 1993:303-16.
    • (1993) Principles, Diagnosis and Therapy , pp. 303-316
    • Köhler, D.1
  • 7
    • 0025638955 scopus 로고
    • Administration médicamenteuse par voie aérienne : Reconsidération de la question
    • CLAUZEL AM, MICHEL FB : Administration médicamenteuse par voie aérienne : reconsidération de la question. Méd Hyg 1990;48:3617-21.
    • (1990) Méd Hyg , vol.48 , pp. 3617-3621
    • Clauzel, A.M.1    Michel, F.B.2
  • 8
    • 8244233326 scopus 로고
    • The effect of furosemide and bumetanide in exercise induced asthma
    • DUGGAN CJ, DIXON CMS, IND PW : The effect of furosemide and bumetanide in exercise induced asthma. Am Rev Respir Dis 1990;141:A474.
    • (1990) Am Rev Respir Dis , vol.141
    • Duggan, C.J.1    Dixon, C.M.S.2    Ind, P.W.3
  • 9
    • 0025761712 scopus 로고
    • Effect of inhaled furosemide and bumetanide on adenosine 5′-monophosphate-and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects
    • O'CONNOR BJ, CHUNG KF, CHEN-WORSDELL YM, FULLER RW, BARNES PJ : Effect of inhaled furosemide and bumetanide on adenosine 5′-monophosphate-and sodium metabisulfite-induced bronchoconstriction in asthmatic subjects. Am Rev Respir Dis 1991;143:1329-33.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1329-1333
    • O'Connor, B.J.1    Chung, K.F.2    Chen-Worsdell, Y.M.3    Fuller, R.W.4    Barnes, P.J.5
  • 10
    • 0024455058 scopus 로고
    • Protective effect of inhaled furosemide on allergen-induced early and late asthmatic reactions
    • BIANCO S, PIERONI MG, REFINI RM, ROTTOLI L, SESTINI P : Protective effect of inhaled furosemide on allergen-induced early and late asthmatic reactions. N Engl J Med 1989;321:1069-73.
    • (1989) N Engl J Med , vol.321 , pp. 1069-1073
    • Bianco, S.1    Pieroni, M.G.2    Refini, R.M.3    Rottoli, L.4    Sestini, P.5
  • 11
    • 0026093368 scopus 로고
    • Inhaled furosemide prevents both the bronchoconstriction and the increase in neutrophil chemotactic activity induced by ultrasonic « fog » of distilled water in asthmaticc
    • MOSCATO G, DELLABIANCA A, FALAGIANI P, MISTRELLO G, ROSSI G,RAMPULA C : Inhaled furosemide prevents both the bronchoconstriction and the increase in neutrophil chemotactic activity induced by ultrasonic « fog » of distilled water in asthmaticc. Am Rev Respir Dis 1991;143:561-6.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 561-566
    • Moscato, G.1    Dellabianca, A.2    Falagiani, P.3    Mistrello, G.4    Rossi, G.5    Rampula, C.6
  • 13
    • 0027427418 scopus 로고
    • Inhaled furosemide prevents ultrasonography nebulized water bronchoconstriction in children with both alopic and nonatopic asthma
    • SHIMUZU T, MOCHIZUKI H, MORIKAWA A, KUROUME T : Inhaled furosemide prevents ultrasonography nebulized water bronchoconstriction in children with both alopic and nonatopic asthma. Chest 1993;104:1723-26.
    • (1993) Chest , vol.104 , pp. 1723-1726
    • Shimuzu, T.1    Mochizuki, H.2    Morikawa, A.3    Kuroume, T.4
  • 14
    • 0026455962 scopus 로고
    • Diurétiques de l'anse et traitement de l'asthme
    • POPIN E, PAULI G: Diurétiques de l'anse et traitement de l'asthme; Rev Mal Respir 1992;9:491-4.
    • (1992) Rev Mal Respir , vol.9 , pp. 491-494
    • Popin, E.1    Pauli, G.2
  • 15
    • 0025166837 scopus 로고
    • Effect of inhaled furosemide on metabisulfite- And methacholine-induced bronchoconstriction and nasal potential difference in asthmatic subjects
    • NICHOL GM, ALTON EWFW, NIX A, GEDDES DM, CHUNC KF, BARNES PJ : Effect of inhaled furosemide on metabisulfite- and methacholine-induced bronchoconstriction and nasal potential difference in asthmatic subjects. Am Rev Respir Dis 1990;142:576-80.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 576-580
    • Nichol, G.M.1    Alton, E.W.F.W.2    Nix, A.3    Geddes, D.M.4    Chunc, K.F.5    Barnes, P.J.6
  • 16
    • 0027976712 scopus 로고
    • Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro
    • VERLEDEN GM, PYPE JL, DEMEDTS MG: Furosemide and bumetanide, but not nedocromil sodium, modulate nonadrenergic relaxation in guinea pig trachea in vitro. Am J Respir Crit Care Med 1994;149:138-44.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 138-144
    • Verleden, G.M.1    Pype, J.L.2    Demedts, M.G.3
  • 17
    • 0025796920 scopus 로고
    • Loop diuretics inhibit cholinergic and noncholinergic nerves in guinea pig airways
    • ELWOOD W, LÖTVALL JO, BARNES PJ, CHUNG KF : Loop diuretics inhibit cholinergic and noncholinergic nerves in guinea pig airways. Am Rev Respir Dis 1991;143:1340-44.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 1340-1344
    • Elwood, W.1    Lötvall, J.O.2    Barnes, P.J.3    Chung, K.F.4
  • 18
    • 0026488590 scopus 로고
    • Acetazolamide and furosemide attenuate asthma induced by hyperventilation of cold, dry air
    • O'DONNELL WJ, ROSENBERG M, NIVEN RW, DRAZEN JM, ISRAEL E : Acetazolamide and furosemide attenuate asthma induced by hyperventilation of cold, dry air. Am Rev Respir Dis 1992;146:1518-23.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 1518-1523
    • O'Donnell, W.J.1    Rosenberg, M.2    Niven, R.W.3    Drazen, J.M.4    Israel, E.5
  • 19
    • 0027481437 scopus 로고
    • Diuretics and asthma
    • BARNES PJ: Diuretics and asthma. Thorax 1993;48:195-6.
    • (1993) Thorax , vol.48 , pp. 195-196
    • Barnes, P.J.1
  • 21
    • 0028358983 scopus 로고
    • Furosemide and loop diuretics in human asthma
    • LOCKHART A, SLUTSKY AS : Furosemide and loop diuretics in human asthma. Chest 1994;106:244-9.
    • (1994) Chest , vol.106 , pp. 244-249
    • Lockhart, A.1    Slutsky, A.S.2
  • 24
    • 0025274624 scopus 로고
    • Acute and long-term amiloride inhalation in cystic fibrosis lung disease, a rational approach to cystic fibrosis therapy
    • APP EM, KING M, HELFESDRIEDER R, KÖHLER D, MATTHYS H : Acute and long-term amiloride inhalation in cystic fibrosis lung disease, a rational approach to cystic fibrosis therapy. Am Rev Respir Dis 1990;141:605-12.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 605-612
    • App, E.M.1    King, M.2    Helfesdrieder, R.3    Köhler, D.4    Matthys, H.5
  • 25
    • 0019809960 scopus 로고
    • Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis
    • KNOWLES M, GATZY J, BOUCHER R : Increased bioelectric potential difference across respiratory epithelia in cystic fibrosis. N Engl J Med 1981;305:1489-95.
    • (1981) N Engl J Med , vol.305 , pp. 1489-1495
    • Knowles, M.1    Gatzy, J.2    Boucher, R.3
  • 27
    • 0025236867 scopus 로고
    • A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis
    • KNOWLES MR, CHURCH NL, WALTNER WE, YANKASKAS JR, GILLIGAN P, KING M et al. : A pilot study of aerosolized amiloride for the treatment of lung disease in cystic fibrosis. N Engl J Med 1990;322:1189-94.
    • (1990) N Engl J Med , vol.322 , pp. 1189-1194
    • Knowles, M.R.1    Church, N.L.2    Waltner, W.E.3    Yankaskas, J.R.4    Gilligan, P.5    King, M.6
  • 29
    • 85008523729 scopus 로고
    • Dispersion and size distribution of amiloride by metered dose and dry powder inhalers
    • BOUNDY MG, LEITH D, KNOWLES MR : Dispersion and size distribution of amiloride by metered dose and dry powder inhalers. J Aerosol Med 1990;3:233-41.
    • (1990) J Aerosol Med , vol.3 , pp. 233-241
    • Boundy, M.G.1    Leith, D.2    Knowles, M.R.3
  • 31
    • 0023937895 scopus 로고
    • The inhibition of sodium influx attenuates airway response to a specific antigen challenge
    • SOUHRADA M, SOUHRADA MH, SOUHRADA JF : The inhibition of sodium influx attenuates airway response to a specific antigen challenge. Br J Pharmacol 1988;93:884-92.
    • (1988) Br J Pharmacol , vol.93 , pp. 884-892
    • Souhrada, M.1    Souhrada, M.H.2    Souhrada, J.F.3
  • 32
    • 0027450964 scopus 로고
    • Effect of inhaled amiloride on the bronchial response to methacholine and cold air hyperventilation challenges
    • NETZEL M, HOPP RJ, BUZZAS R,DOWLING P, PALMEIRO E, BEWTRA AK : Effect of inhaled amiloride on the bronchial response to methacholine and cold air hyperventilation challenges. Chest 1993;103:484-7.
    • (1993) Chest , vol.103 , pp. 484-487
    • Netzel, M.1    Hopp, R.J.2    Buzzas, R.3    Dowling, P.4    Palmeiro, E.5    Bewtra, A.K.6
  • 34
    • 0025103872 scopus 로고
    • Endogenous opioids modulate the increase in ventilatory output and dyspnea during severe acute bronchoconstriction
    • BELLOFIORE S, DI MARIA GU, PRIVITERA S, SAPIENZA S, MILIC-EMILI J et al. : Endogenous opioids modulate the increase in ventilatory output and dyspnea during severe acute bronchoconstriction. Am Rev Respir Dis 1990;142:812-6.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 812-816
    • Bellofiore, S.1    Di Maria, G.U.2    Privitera, S.3    Sapienza, S.4    Milic-Emili, J.5
  • 35
  • 36
    • 0024545402 scopus 로고
    • Effects of oral morphine on breathlessness and exercise tolerance in patients with chronic obstructive pulmonary disease
    • LIGHT RW, MURO JR, SATO RI, STANSBURY DW, FISCHER CE, BROWN SE : Effects of oral morphine on breathlessness and exercise tolerance in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1989;139:126-33.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 126-133
    • Light, R.W.1    Muro, J.R.2    Sato, R.I.3    Stansbury, D.W.4    Fischer, C.E.5    Brown, S.E.6
  • 37
    • 7344247611 scopus 로고
    • Effect of oral diamorphine on dyspnea in chronic obstructive pulmonary disease
    • EISER N, LUCE P, DENMAN W, WEST C : Effect of oral diamorphine on dyspnea in chronic obstructive pulmonary disease. Am Rev Respir Dis 1990;141:A323.
    • (1990) Am Rev Respir Dis , vol.141
    • Eiser, N.1    Luce, P.2    Denman, W.3    West, C.4
  • 38
    • 0025829903 scopus 로고
    • Lack of effect of dextromethorphan on breathlessness and exercise performance in patients with chronic obstructive pulmonary disease
    • GIRON AE, STANSBURY DW, FISCHER CE, LIGHT RW : Lack of effect of dextromethorphan on breathlessness and exercise performance in patients with chronic obstructive pulmonary disease. Eur Respir J 1991;4:532-5.
    • (1991) Eur Respir J , vol.4 , pp. 532-535
    • Giron, A.E.1    Stansbury, D.W.2    Fischer, C.E.3    Light, R.W.4
  • 39
    • 0025942392 scopus 로고
    • Oral diamorphine : Lack of effect on dyspnoea and exercise tolerance in the « pink puffer » syndrome
    • EISER N, DENMAN WT, WEST C, LUCE P : Oral diamorphine : lack of effect on dyspnoea and exercise tolerance in the « pink puffer » syndrome. Eur Respir J 1991;4:926-31.
    • (1991) Eur Respir J , vol.4 , pp. 926-931
    • Eiser, N.1    Denman, W.T.2    West, C.3    Luce, P.4
  • 40
    • 0024385863 scopus 로고
    • Effect of low dose nebulised morphine on exercise endurance in patients with chronic lung disease
    • YOUNG IH, DAVISKAS E, KEENA VA : Effect of low dose nebulised morphine on exercise endurance in patients with chronic lung disease. Thorax 1989;44:387-90.
    • (1989) Thorax , vol.44 , pp. 387-390
    • Young, I.H.1    Daviskas, E.2    Keena, V.A.3
  • 42
    • 0027259040 scopus 로고
    • Effects of nebulized morphine sulfate on the exercise tolerance of the ventilatory limited COPD patient
    • BEAUFORD W, SAYLOR TT, STANSBURY DW, AVALOS K, LIGHT RW : Effects of nebulized morphine sulfate on the exercise tolerance of the ventilatory limited COPD patient. Chest 1993;104:175-8.
    • (1993) Chest , vol.104 , pp. 175-178
    • Beauford, W.1    Saylor, T.T.2    Stansbury, D.W.3    Avalos, K.4    Light, R.W.5
  • 43
    • 0029072672 scopus 로고
    • Lack of effect of inhaled morphine on exercise-induced breathlessness in chronic obstructive pulmonary disease
    • MASOOD AR, REED JW, THOMAS SHL : Lack of effect of inhaled morphine on exercise-induced breathlessness in chronic obstructive pulmonary disease. Thorax 1995; 50:629-34.
    • (1995) Thorax , vol.50 , pp. 629-634
    • Masood, A.R.1    Reed, J.W.2    Thomas, S.H.L.3
  • 46
    • 0025783341 scopus 로고
    • Organ specific cytokine therapy, local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-γ to the human lung
    • JAFFE HA, BUHL R, MASTRANGELI A, HOLROYD KJ, SALTINI C, CZERSKI D et al. : Organ specific cytokine therapy, local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-γ to the human lung. J Clin Invest 1991;88:297-302.
    • (1991) J Clin Invest , vol.88 , pp. 297-302
    • Jaffe, H.A.1    Buhl, R.2    Mastrangeli, A.3    Holroyd, K.J.4    Saltini, C.5    Czerski, D.6
  • 47
    • 0024407508 scopus 로고
    • Pharmacokinetics and toxicity of inhaled human interferon-α in patients with lung cancer
    • KINNULA V, MATTSON K, CANTELL K : Pharmacokinetics and toxicity of inhaled human interferon-α in patients with lung cancer. J Interferon Res 1989;9:419-23.
    • (1989) J Interferon Res , vol.9 , pp. 419-423
    • Kinnula, V.1    Mattson, K.2    Cantell, K.3
  • 48
    • 0028820963 scopus 로고
    • Inhaled recombinant interferon gamma in patients with lung cancer : Pharmacokinetics and effects on chemiluminescence response of alveolar macrophages and peripheral blood neutrophils and monocytes
    • HALME M, MAASILTA P, REPO H, RISTOLA M, TASKINEN E, MATTSON K et al. : Inhaled recombinant interferon gamma in patients with lung cancer : pharmacokinetics and effects on chemiluminescence response of alveolar macrophages and peripheral blood neutrophils and monocytes. Int J Radiation Oncology Biol Phys 1995;31:93-101.
    • (1995) Int J Radiation Oncology Biol Phys , vol.31 , pp. 93-101
    • Halme, M.1    Maasilta, P.2    Repo, H.3    Ristola, M.4    Taskinen, E.5    Mattson, K.6
  • 49
    • 0023936158 scopus 로고
    • Lung-specific delivery of cytokines induces sustained pulmonary and systemic immunomodulation in rats
    • DEBS RJ, FUCHS HJ, PHILIP R, MONTGOMERY AB, BRUNETTE EN, LIGGITT D et al. : Lung-specific delivery of cytokines induces sustained pulmonary and systemic immunomodulation in rats. J Immunol 1988;140:3482-8.
    • (1988) J Immunol , vol.140 , pp. 3482-3488
    • Debs, R.J.1    Fuchs, H.J.2    Philip, R.3    Montgomery, A.B.4    Brunette, E.N.5    Liggitt, D.6
  • 51
    • 0002996405 scopus 로고
    • Combined betaseron (recombinant human interferon beta) and radiation for inoperable non-small cell lung cancer
    • MCDONNALD S, RUBIN P, CHANG A, WALLENBERG J, KIM IS, SOBEL S et al. : Combined betaseron (recombinant human interferon beta) and radiation for inoperable non-small cell lung cancer. Int J Radiat Oncol Biol Phys 1992;suppl24:192.
    • (1992) Int J Radiat Oncol Biol Phys , vol.24 SUPPL , pp. 192
    • Mcdonnald, S.1    Rubin, P.2    Chang, A.3    Wallenberg, J.4    Kim, I.S.5    Sobel, S.6
  • 52
    • 0028178096 scopus 로고
    • Intratracheal interferon-γ augments pulmonary defenses in experimental legionellosis
    • SKERRETT SJ, MARTIN TR: Intratracheal interferon-γ augments pulmonary defenses in experimental legionellosis. Am J Respir Crit Care Med 1994;149:50-8.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 50-58
    • Skerrett, S.J.1    Martin, T.R.2
  • 55
  • 56
    • 0027445457 scopus 로고
    • Characterization and administration of cyclosporine liposomes as a small-particle aerosol
    • GILBERT BE, WILSON SZ, GARCON NM, WYDE PR, KNIGHT V : Characterization and administration of cyclosporine liposomes as a small-particle aerosol. Transplantation 1993;56:974-7.
    • (1993) Transplantation , vol.56 , pp. 974-977
    • Gilbert, B.E.1    Wilson, S.Z.2    Garcon, N.M.3    Wyde, P.R.4    Knight, V.5
  • 59
    • 0026569474 scopus 로고
    • Improved immunosuppression with aerosolized cyclosporine in experimental pulmonary transplantation
    • KEENAN RJ, DUNCAN AJ, YOUSEM SA, ZENATI M, SCHAPER M, DOWLING RD et al. : Improved immunosuppression with aerosolized cyclosporine in experimental pulmonary transplantation. Transplantation 1992;53:20-5.
    • (1992) Transplantation , vol.53 , pp. 20-25
    • Keenan, R.J.1    Duncan, A.J.2    Yousem, S.A.3    Zenati, M.4    Schaper, M.5    Dowling, R.D.6
  • 61
    • 0029165887 scopus 로고
    • Efficacy of inhaled cyclosporine in lung transplant recipients with refractory rejection : Correlation of intragraft cytokine gene expression with pulmonary function and histologic characteristics
    • KEENAN RJ, ZEEVI A, IACONO AT, SPICHTY KJ, CAI Z-JJ, YOUSSEM SA : Efficacy of inhaled cyclosporine in lung transplant recipients with refractory rejection : correlation of intragraft cytokine gene expression with pulmonary function and histologic characteristics. Surgery 1995;118:385-91.
    • (1995) Surgery , vol.118 , pp. 385-391
    • Keenan, R.J.1    Zeevi, A.2    Iacono, A.T.3    Spichty, K.J.4    Cai, Z.-J.J.5    Youssem, S.A.6
  • 62
    • 0023470788 scopus 로고
    • The place of prostacyclin in the clinical management of primary hypertension
    • HIGENBOTTAM T: The place of prostacyclin in the clinical management of primary hypertension. Am Rev Respir Dis 1987;136:782-5.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 782-785
    • Higenbottam, T.1
  • 63
    • 0023264362 scopus 로고
    • The effects of vasodilatation with prostacyclin on oxygen delivery and uptake in critically ill patients
    • BIHARI D, SMITHIES M, GIMSON A, TINKER J : The effects of vasodilatation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med 1987;317: 397-403.
    • (1987) N Engl J Med , vol.317 , pp. 397-403
    • Bihari, D.1    Smithies, M.2    Gimson, A.3    Tinker, J.4
  • 64
    • 0024476896 scopus 로고
    • 1 in adult respiratory distress syndrome. Benefit for pulmonary hypertension and cost for pulmonary gas exchange
    • 1 in adult respiratory distress syndrome. Benefit for pulmonary hypertension and cost for pulmonary gas exchange. Am Rev Respir Dis 1989;139:106-10.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 106-110
    • Mélot, C.1    Lejeune, P.2    Leeman, M.3    Moraine, J.J.4    Naeije, R.5
  • 65
    • 0025356811 scopus 로고
    • Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial
    • RUBIN LJ, MENDOZA J, HOOD M, MCGOON M, BARST R, WILLIAMS WB et al. : Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol). Results of a randomized trial. Ann Internj Med 1990;112:485-91.
    • (1990) Ann Internj Med , vol.112 , pp. 485-491
    • Rubin, L.J.1    Mendoza, J.2    Hood, M.3    Mcgoon, M.4    Barst, R.5    Williams, W.B.6
  • 66
    • 0028597038 scopus 로고
    • Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin
    • BARST RJ, RUBIN LJ, MCGOON M, CALDWELL EJ, LONG WA, LEVEY PS : Survival in primary pulmonary hypertension with long-term continuous intravenous prostacyclin. Ann Intern Med 1994;121:409-15.
    • (1994) Ann Intern Med , vol.121 , pp. 409-415
    • Barst, R.J.1    Rubin, L.J.2    Mcgoon, M.3    Caldwell, E.J.4    Long, W.A.5    Levey, P.S.6
  • 67
    • 0030031888 scopus 로고    scopus 로고
    • A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension
    • BARST RJ, RUBIN LJ, LONG WA et al. : A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. N Engl J Med 1996;334:296-301.
    • (1996) N Engl J Med , vol.334 , pp. 296-301
    • Barst, R.J.1    Rubin, L.J.2    Long, W.A.3
  • 68
  • 71
    • 0026756945 scopus 로고
    • Systèmes d'administration d'insuline, possibilités et difficultés
    • SELAM JL, SLAMA G : Systèmes d'administration d'insuline, possibilités et difficultés. Presse Méd 1992;21:1575-80.
    • (1992) Presse Méd , vol.21 , pp. 1575-1580
    • Selam, J.L.1    Slama, G.2
  • 72
    • 0020050679 scopus 로고
    • Insulin given intranasally induces hypoglycaemia in normal and diabetic subjects
    • HANKISS J : Insulin given intranasally induces hypoglycaemia in normal and diabetic subjects. Br Med J 1982;284:1707-8.
    • (1982) Br Med J , vol.284 , pp. 1707-1708
    • Hankiss, J.1
  • 73
    • 0020051102 scopus 로고
    • Insulin given intranasally induces hypoglycaemia in normal and diabetic subjects
    • PONTIROLI AE, ALBERETTO M, SECCHI A, DOSSI G, BOSI I, POZZA G : Insulin given intranasally induces hypoglycaemia in normal and diabetic subjects. Br Med J 1982;284:303-6.
    • (1982) Br Med J , vol.284 , pp. 303-306
    • Pontiroli, A.E.1    Alberetto, M.2    Secchi, A.3    Dossi, G.4    Bosi, I.5    Pozza, G.6
  • 74
    • 0021034494 scopus 로고
    • Insulin administered intranasally as an insulin-bile salt aerosol : Effectiveness and reproducibility in normal and diabetic subjects
    • MOSES AC, GORDON GS, CAREY MC, FLIER JS : Insulin administered intranasally as an insulin-bile salt aerosol : effectiveness and reproducibility in normal and diabetic subjects. Diabetes 1983;32:1040-7.
    • (1983) Diabetes , vol.32 , pp. 1040-1047
    • Moses, A.C.1    Gordon, G.S.2    Carey, M.C.3    Flier, J.S.4
  • 75
    • 0021918027 scopus 로고
    • Intranasal aerosolized insulin, mixed-meal studies and long-term use in type I diabetes
    • SALZMAN R, MANSON JE, GRIFFING GT, KIMMERLE R, RUDERMAN N, MCCALL A et al. : Intranasal aerosolized insulin, mixed-meal studies and long-term use in type I diabetes. N Engl J Med 1985;312:1078-84.
    • (1985) N Engl J Med , vol.312 , pp. 1078-1084
    • Salzman, R.1    Manson, J.E.2    Griffing, G.T.3    Kimmerle, R.4    Ruderman, N.5    Mccall, A.6
  • 77
    • 0023616681 scopus 로고
    • Preprandial intranasal insulin as adjuvant in the type II diabetics
    • EL-ETR M, SLAMA G, DESPLANQUE N : Preprandial intranasal insulin as adjuvant in the type II diabetics. Lancet 1987;ii:1085-6.
    • (1987) Lancet , vol.2 , pp. 1085-1086
    • El-Etr, M.1    Slama, G.2    Desplanque, N.3
  • 78
    • 0017250017 scopus 로고
    • Development of an aerosol form containing insulin
    • LEE SW, SCIARRA JJ : Development of an aerosol form containing insulin. J Pharm Sci 1976;65:567-72.
    • (1976) J Pharm Sci , vol.65 , pp. 567-572
    • Lee, S.W.1    Sciarra, J.J.2
  • 79
    • 0000859938 scopus 로고
    • Pulmonary administration of human insulin in volunteers and type I-diabetics
    • SCHLÜTER KJ, KÖHLER D, ENZMAN F, KERP L : Pulmonary administration of human insulin in volunteers and type I-diabetics. Diabetes 1984;suppl:75A.
    • (1984) Diabetes , vol.SUPPL
    • Schlüter, K.J.1    Köhler, D.2    Enzman, F.3    Kerp, L.4
  • 81
    • 0027506440 scopus 로고
    • Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients
    • LAUBE BL, GEORGOPOULOS A, ADAMS GK : Preliminary study of the efficacy of insulin aerosol delivered by oral inhalation in diabetic patients. JAMA 1993;269:2106-9.
    • (1993) JAMA , vol.269 , pp. 2106-2109
    • Laube, B.L.1    Georgopoulos, A.2    Adams, G.K.3
  • 82
    • 0023705847 scopus 로고
    • Absorption of recombinant methionyl-human growth hormone (Met-hGH) from rat nasal mucosa
    • DAUGHERTY AL, LIGGITT HD, MCCABE JG, MOORE JA, PATTON JS : Absorption of recombinant methionyl-human growth hormone (Met-hGH) from rat nasal mucosa. Int J Pharm 1988;45:197-206.
    • (1988) Int J Pharm , vol.45 , pp. 197-206
    • Daugherty, A.L.1    Liggitt, H.D.2    Mccabe, J.G.3    Moore, J.A.4    Patton, J.S.5
  • 84
    • 0028931388 scopus 로고
    • The influence of regional deposition on the pharmacokinetics of pulmonary-delivered human growth hormone in rabbits
    • COLTHORPE P, FARR SJ, SMITH IJ, WYATT D, TAYLOR G : The influence of regional deposition on the pharmacokinetics of pulmonary-delivered human growth hormone in rabbits. Pharm Res 1995;12:356-9.
    • (1995) Pharm Res , vol.12 , pp. 356-359
    • Colthorpe, P.1    Farr, S.J.2    Smith, I.J.3    Wyatt, D.4    Taylor, G.5
  • 85
    • 0026543325 scopus 로고
    • Bioavailability of leuprolide acetate following nasal and inhalation delivery to rats and healthy humans
    • ADJEI A, SUNDBERG D, MILLER J, CHUN A : Bioavailability of leuprolide acetate following nasal and inhalation delivery to rats and healthy humans. Pharm Res 1992;9:244-9.
    • (1992) Pharm Res , vol.9 , pp. 244-249
    • Adjei, A.1    Sundberg, D.2    Miller, J.3    Chun, A.4
  • 86
    • 0025100418 scopus 로고
    • Pulmonary delivery of peptide drugs : Effect of particle size on bioavailability of leuprolide acetate in healthy male volunteers
    • ADJEI A, GARREN J : Pulmonary delivery of peptide drugs : effect of particle size on bioavailability of leuprolide acetate in healthy male volunteers. Pharma Res 1990;7:565-9.
    • (1990) Pharma Res , vol.7 , pp. 565-569
    • Adjei, A.1    Garren, J.2
  • 87
    • 0027965843 scopus 로고
    • Study on pulmonary delivery of salmon calcitonin in rats : Effects of protease inhibitors and absorption enhancers
    • KOBAYASHI S, KONDO S, JUNI K : Study on pulmonary delivery of salmon calcitonin in rats : effects of protease inhibitors and absorption enhancers. Pharm Res 1994;11: 1239-43.
    • (1994) Pharm Res , vol.11 , pp. 1239-1243
    • Kobayashi, S.1    Kondo, S.2    Juni, K.3
  • 88
    • 0028135638 scopus 로고
    • Prevention of further bone mass loss by nasal calcitonin in patients on long term glucocorticoid therapyp for asthma : A two year follow up study
    • LUENGO M, PONS F, DE OSABA MJM, PICADO C : Prevention of further bone mass loss by nasal calcitonin in patients on long term glucocorticoid therapyp for asthma : a two year follow up study. Thorax 1994;49:1099-102.
    • (1994) Thorax , vol.49 , pp. 1099-1102
    • Luengo, M.1    Pons, F.2    De Osaba, M.J.M.3    Picado, C.4
  • 89
    • 0027159807 scopus 로고
    • Prevention of corticosteroid osteoporosis. a comparison of calcium, calcitriol, and calcitonin
    • SAMBROOK P, BIRMINGHAM J, KELLY P, KEMPLER S, NGUYEN T, POCOCK N et al. : Prevention of corticosteroid osteoporosis. a comparison of calcium, calcitriol, and calcitonin. N Engl J Med 1993;328:1747-52.
    • (1993) N Engl J Med , vol.328 , pp. 1747-1752
    • Sambrook, P.1    Birmingham, J.2    Kelly, P.3    Kempler, S.4    Nguyen, T.5    Pocock, N.6
  • 91
    • 0026671983 scopus 로고
    • Effect of salcatonin given intranasally on bone mass and fracture rates in established osteoporosis : A dose-response study
    • OVERGAARD K, HANSEN MA, JENSEN SB, CHRISTIANSEN C : Effect of salcatonin given intranasally on bone mass and fracture rates in established osteoporosis : a dose-response study. Br Med J 1992;305:556-61.
    • (1992) Br Med J , vol.305 , pp. 556-561
    • Overgaard, K.1    Hansen, M.A.2    Jensen, S.B.3    Christiansen, C.4
  • 92
    • 0025855877 scopus 로고
    • Calcitonin nasal spray in patients with chronic asthma : A double-blind crossover study vs placebo
    • NEGRO RD, TURCO P, POMARY C, TREVISAN F: Calcitonin nasal spray in patients with chronic asthma : a double-blind crossover study vs placebo. Int J Clin Pharmacol Ther Toxicol 1991;29:144-6.
    • (1991) Int J Clin Pharmacol Ther Toxicol , vol.29 , pp. 144-146
    • Negro, R.D.1    Turco, P.2    Pomary, C.3    Trevisan, F.4
  • 94
    • 0024345992 scopus 로고
    • Pharmacological approach to smoking cessation
    • PRIGNOT J : Pharmacological approach to smoking cessation. Eur Respirf J 1989;2:550-60.
    • (1989) Eur Respirf J , vol.2 , pp. 550-560
    • Prignot, J.1
  • 97
    • 9844234347 scopus 로고
    • Effect of aerosol particle size on nicotine absorption and side effects produced by nicotine aerosol
    • BURCH SG, GANN LP, OLSEN KM, ERBLAND ML, HILLER FC : Effect of aerosol particle size on nicotine absorption and side effects produced by nicotine aerosol. Am Rev Respir Dis 1989;139:A339.
    • (1989) Am Rev Respir Dis , vol.139
    • Burch, S.G.1    Gann, L.P.2    Olsen, K.M.3    Erbland, M.L.4    Hiller, F.C.5
  • 99
    • 0018566713 scopus 로고
    • Anticoagulant activity and operative blood loss after intrapulmonary heparin
    • WRIGHT CJ, MAHADOO J, JACQUES LB : Anticoagulant activity and operative blood loss after intrapulmonary heparin. Br J Surg 1979;66:844-7.
    • (1979) Br J Surg , vol.66 , pp. 844-847
    • Wright, C.J.1    Mahadoo, J.2    Jacques, L.B.3
  • 100
    • 0017120034 scopus 로고
    • Intrapulmonary heparin, a new procedure for anticoagulant therapy
    • JACQUES LB, MAHADOO J, KAVANAGH LW : Intrapulmonary heparin, a new procedure for anticoagulant therapy. Lancet 1976;27:1157-61.
    • (1976) Lancet , vol.27 , pp. 1157-1161
    • Jacques, L.B.1    Mahadoo, J.2    Kavanagh, L.W.3
  • 101
    • 0022254953 scopus 로고
    • Clinical use of intrapulmonary heparin
    • BICK RL, Ross ES : Clinical use of intrapulmonary heparin. Semin Thromb Hemost 1985;11:213-7.
    • (1985) Semin Thromb Hemost , vol.11 , pp. 213-217
    • Bick, R.L.1    Ross, E.S.2
  • 102
    • 0019274454 scopus 로고
    • Endothelial sequestration of heparin administered by the intrapulmonary route
    • MAHADOO J, HIEBERT LM, JACQUES LB, WRIGHT CJ : Endothelial sequestration of heparin administered by the intrapulmonary route. Artery 1980;7(5):438-47.
    • (1980) Artery , vol.7 , Issue.5 , pp. 438-447
    • Mahadoo, J.1    Hiebert, L.M.2    Jacques, L.B.3    Wright, C.J.4
  • 104
    • 0028672457 scopus 로고
    • Aerosolized heparin
    • KÖHLER D : Aerosolized heparin. J Aerosol Med 1994;7:307-14.
    • (1994) J Aerosol Med , vol.7 , pp. 307-314
    • Köhler, D.1
  • 105
    • 0023754431 scopus 로고
    • Heparin for prevention of atherosclerosis
    • SHULMAN AG : Heparin for prevention of atherosclerosis. N Eng J Med 1988;319:1154-5.
    • (1988) N Eng J Med , vol.319 , pp. 1154-1155
    • Shulman, A.G.1
  • 106
    • 0027215483 scopus 로고
    • Non-anticoagulant uses of heparin
    • LANE DA, ADAMS L : Non-anticoagulant uses of heparin. N Engl J Med 1993;329:129-30.
    • (1993) N Engl J Med , vol.329 , pp. 129-130
    • Lane, D.A.1    Adams, L.2
  • 107
    • 0026596865 scopus 로고
    • Effects of inhaled heparin on immunologic and nonimmunologic bronchoconstrictor responses in sheep
    • AHMED T, ABRAHAM WM, D'BROT J : Effects of inhaled heparin on immunologic and nonimmunologic bronchoconstrictor responses in sheep. Am Rev Respir Dis 1992;145:566-10.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 566-610
    • Ahmed, T.1    Abraham, W.M.2    D'Brot, J.3
  • 109
    • 9844254577 scopus 로고
    • Eosinophil cationic protein in sputum from asthmatic patients with sputum eosinophilia
    • VIRCHOW JR JC, VENGE P, VIRCHOW SEN C: Eosinophil cationic protein in sputum from asthmatic patients with sputum eosinophilia. Am Rev Respir Dis 1991;143:A41.
    • (1991) Am Rev Respir Dis , vol.143
    • Virchow Jr., J.C.1    Venge, P.2    Virchow Sen, C.3
  • 110
    • 9844234346 scopus 로고
    • Beneficial effects of heparin after smoke inhalation injury not due to decreased oxygen free radical activity
    • COX CS, ZWISCHENBERGER JB, TRABER DL, TRABER LD, HERNDON DN : Beneficial effects of heparin after smoke inhalation injury not due to decreased oxygen free radical activity. Am Rev Respir Dis 1992;145:A80.
    • (1992) Am Rev Respir Dis , vol.145
    • Cox, C.S.1    Zwischenberger, J.B.2    Traber, D.L.3    Traber, L.D.4    Herndon, D.N.5
  • 111
    • 0027159470 scopus 로고
    • Preventing bronchoconstriction in exercise-induced asthma with inhaled heparin
    • AHMED T, GARRIGO J, DANTA I : Preventing bronchoconstriction in exercise-induced asthma with inhaled heparin. N Engl J Med 1993;329:90-5.
    • (1993) N Engl J Med , vol.329 , pp. 90-95
    • Ahmed, T.1    Garrigo, J.2    Danta, I.3
  • 112
    • 0028911135 scopus 로고
    • Effect of inhaled heparin on methacholine-induced bronchial hyperreactivity
    • CEYHAN B, CELIKEL T : Effect of inhaled heparin on methacholine-induced bronchial hyperreactivity. Chest 1995; 107:1009-12.
    • (1995) Chest , vol.107 , pp. 1009-1012
    • Ceyhan, B.1    Celikel, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.