Inhibition of harringtonine-induced apoptosis by tetradecanoylphorbol acetate in human leukemia HL-60 cells

Acta Pharmacologica Sinica

Volumn 18, Issue 5, 1997, Pages 459-462

  Meng, Fan Hong ^a   He, Qi Yang ^a   Zhang, Hong Qing ^a   Xue, Shao Bai ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

Author keywords

apoptosis; Camptothecin; Harringtonines; HL 60 cells; Myc genes; Tetradecanoylphorbol acetate

Indexed keywords

CAMPTOTHECIN; HARRINGTONINE; PHORBOL 13 ACETATE 12 MYRISTATE;

APOPTOSIS; ARTICLE; CELL STRAIN HL 60; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOMETRY; DOT HYBRIDIZATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL; ONCOGENE C MYC;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAMPTOTHECIN; CARCINOGENS; GENE EXPRESSION REGULATION; GENES, MYC; HARRINGTONINES; HL-60 CELLS; HUMANS; TETRADECANOYLPHORBOL ACETATE;

EID: 0030798377     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (13)

1. Fang M, Zhang HQ, Xue SB, Pang DB, Chi XS. Induction of apoptosis in HL-60 cells by harringtonine. Chin Sci Bull 1995; 40: 939-44.
2. Bertrand R, Solary E, Jenkins J, Pommier Y. Apoptosis and its modulation in human promyelocytic HL-60 cells treated with DNA topoisomerase I and II inhibitors. Exp Cell Res 1993; 207: 388-97.
3. Ikemoto H, Tani E, Matsumoto T, Nakano A, Furuyama J-I. Apoptosis of human glioma cells in response to calphostin C, a specific protein kinase C inhibitor. J Neurosurg 1995; 83: 1008-16.
4. Motyka B, Griebel PJ, Reynolds JD. Agents that activate protein kinase C rescue sheep ileal Peyer's patch B cells from apoptosis. Eur J Immunol 1993; 23: 1314-21.
5. McConkey DJ, Hartzell P, Jondal M, Orrenius S. Inhibition of DNA fragmentation in thymocytes and isolated thymocyte nuclei by agents that stimulate protein kinase C. J Biol Chem 1989; 264: 13399-402.
6. Zhou WD, Zhang HQ, Fang M, Xue SB. Studies with flow cytometry on the regulation of PKC and reversal effects of VRP, CsA on multidrug resistant cell lines. J Beijing Normal Univ (Natural Sci) 1996; 32: 129-33.
7. Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, et al. Induction of apoptosis in fibroblasts by c-myc protein. Cell 1992; 69: 119-28.
8. Zhou WD, Zhang HQ, Fang M, Xue SB. Correlation between expression of mdr-1 gene and oncogenes in human promyelocytic leukemic HL60 cell line and sublines. Acta Pharmacol Sin 1996; 17: 471-3.
9. He QY, Zhang HQ, Pang DB, Chi XS, Xue SB. Resistance to apoptosis of harringtonine-resistant HL60 cells induced by tetrandrine. Acta Pharmacol Sin 1996; 17: 515-9.
10. Wu GY, Fang FD, Zuo J. Preliminary studies on mechanism of inhibition of protein synthesis by harringtonine. Acta Pharm Sin 1984; 19: 167-72.
11. Hsiang YH, Liu LF. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 1988; 48: 1722-6.
12. 3 protects HL60 cells against apoptosis but down-regulates the expression of the bcl-2 gene. Exp Cell Res 1993; 209: 367-74.
13. McCarthy JV, Fernandes RS, Gotter TG. Increased resistance to apoptosis associated with HL-60 myeloid differentiation status. Anticancer Res 1994; 14: 2063-72.