Optimal ratios of biliary glycoprotein isoforms required for inhibition of colonic tumor cell growth

Cancer Research

Volumn 57, Issue 13, 1997, Pages 2781-2788

  Turbide, Claire ^a   Kunath, Tilo ^a   Daniels, Eugene ^b   Beauchemin, Nicole ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; GLYCOPROTEIN;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL SURFACE; GROWTH INHIBITION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ANTIGENS, CD; CELL ADHESION MOLECULES; CELL TRANSFORMATION, NEOPLASTIC; COLON; COLONIC NEOPLASMS; FEMALE; GLYCOPROTEINS; INTESTINAL MUCOSA; MICE; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0030797459     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Svenberg, T. Carcinoembryonic antigen-like substances of human bile. Isolation and partial characterization. Int. J. Cancer, 17: 588-596, 1976.
2. Thompson, J. A., Grunert, F., and Zimmermann, W. Carcinoembryonic antigen gene family: molecular biology and clinical perspectives. J. Clin. Lab. Anal., 5: 344-366, 1991.
3. McCuaig, K., Turbide, C., and Beauchemin, N. mmCGM1a: a mouse earcinoembryonic antigen gene family member, generated by alternative splicing, functions as an adhesion molecule. Cell Growth & Differ., 3: 165-174, 1992.
4. Prall, F., Nollau, P., Neumaier, M., Haubeck, H. D., Drzeniek, Z., Helmchen, U., Löning, T., and Wagener, C. CD66a (BGP), an adhesion molecule of the Carcinoembryonic antigen family, is expressed in epithelium, endothelium, and myeloid cells in a wide range of normal human tissues. J. Histochem. Cytochem., 44: 35-41, 1996.
5. Öbrink, B. C-CAM (cell CAM 105): a member of the growing immunoglobulin superfamily of cell adhesion proteins. Bioessays, 13: 227-234, 1991.
6. 2+ -dependent intercellular adhesion molecule. Cell Growth & Differ., 1: 527-533, 1990.
7. Turbide, C., Rojas, M., Stanners, C. P., and Beauchemin, N. A mouse Carcinoembryonic antigen gene family member is a calcium-dependent cell adhesion molecule. J. Biol. Chem., 266: 309-315, 1991.
8. 2+-independent cell adhesion activities of biliary glycoprotein, a member of Carcinoembryonic antigen family, expressed on CHO cell surface. Biochem. Biophys. Res. Commun., 186: 881-887, 1992.
9. Formisano, P., Najjar, S. M., Gross, C. N., Philippe, N., Oriente, F., Kern-Buell, C. L., Accili, D., and Gorden, P. Receptor-mediated internalization of insulin. J. Biol. Chem., 270: 24073-24077, 1995.
10. Lin, S-H., and Guidotti, G. Cloning and expression of a cDNA coding for a rat liver plasma membrane ecto-ATPase. J. Biol. Chem., 264: 14408-14414, 1989.
11. Sippel, C. J., Suchy, F. J., Ananthanarayanan, M., and Perlmutter, D. H. The rat liver ecto-ATPase is also a canalicular bile acid transport protein. J. Biol. Chem., 268: 2083-2091, 1993.
12. Dveksler, G. S., Pensiero, M. N., Cardellichio, C. B., Williams, R. K., Jiang, G. S., Holmes, K. V., and Dieffenbach, C. W. Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J. Virol., 65: 6881-6891, 1991.
13. Dveksler, G. S., Dieffenbach, C. W., Cardellichio, C. B., McCuaig, K., Pensiero, M. N., Jiang, G. S., Beauchemin, N., and Holmes, K. V. Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59. J. Virol., 67: 1-8, 1993.
14. c-src with biliary glycoprotein (CD66a), an adhesion molecule of the carcinoembryonic antigen family downregulated in colorectal carcinomas. Oncogene, 11: 1649-1655, 1995.
15. Skubitz, K. M., Campbell, K. D., Ahmed, K., and Skubitz, A. P. N. CD66 family members are associated with tyrosine kinase activity in human neutrophils. J. Immunol., 151: 5382-5390, 1995.
16. Sippel, C. J., Fallon, R. J., and Perlmutter, D. H. Bile acid efflux mediated by the rat liver canalicular bile acid transport/ecto-ATPase protein requires serine 503 phosphorylation and is regulated by tyrosine 488 phosphorylation. J. Biol. Chem., 269: 19539-19545, 1994.
17. Najjar, S. M., Philippe, N., Suzuki, Y., Ignacio, G. A., Formisano, P., Accili, D., and Taylor, S. I. Insulin-stimulated phosphorylation of recombinant pp120/HA4, an endogenous substrate of the insulin receptor tyrosine kinase. Biochemistry, 34: 9341-9349, 1995.
18. Beauchemin, N., Kunath, T., Robitaille, J., Chow, B., Turbide, C., Daniels, E., and Veillette, A. Association of biliary glycoprotein with protein tyrosine phosphatase SHP-1 in malignant colon epithelial cells. Oncogene, 14: 783-790, 1997.
19. Barnett, T., Kretschmer, A., Austen, D. A., Goebel, S. J., Hart, J. T., Elting, J. J., and Kamarck, M. E. Carcinoembryonic antigens: alternative splicing accounts for the multiple mRNAs that code for novel members of the carcinoembryonic antigen family. J. Cell Biol., 108: 267-276, 1989.
20. Edlund, M., Gaardsvoll, H., Bock, E., and Öbrink, B. Different isoforms and stock-specific variants of the cell adhesion molecule C-CAM (cell-CAM 105) in rat liver. Eur. J. Biochem., 213: 1109-1116, 1993.
21. Najjar, S. M., Accili, D., Philippe, N., Jernberg, J., Margolis, R., and Taylor, S. I. pp120/ecto-ATPase, an endogenous substrate of the insulin receptor tyrosine kinase, is expressed as two variably spliced isoforms. J. Biol. Chem., 268: 1201-1206, 1993.
22. Nédellec, P., Turbide, C., and Beauchemin, N. Characterization and transcriptional activity of the mouse biliary glycoprotein 1 gene, a carcinoembryonic antigen-related gene. Eur. J. Biochem., 231: 104-114, 1995.
23. Kunath, T., Ordoñez-Garcia, C., Turbide, C., and Beauchemin, N. Inhibition of colonic tumor cell growth by biliary glycoprotein. Oncogene, 11: 2375-2382, 1995.
24. Hsieh, J-T., Luo, W., Song, W., Wang, Y., Kleinerman, D. I., Van, N. T., and Lin, S-H. Tumor suppressive role of an androgen-regulated epithelial cell adhesion molecule (C-CAM) in prostate carcinoma cell revealed by sense and antisense approaches. Cancer Res., 55: 190-197, 1995.
25. Neumaier, M., Paululat, S., Chan, A., Matthaes, P., and Wagener, C. Biliary glycoprotein, a potential human cell adhesion molecule, is down-regulated in colorectal carcinomas. Proc. Natl. Acad. Sci. USA, 90: 10744-10748, 1993.
26. Rosenberg, M., Nédellec P., Jothy, S., Fleiszer, D., Turbide, C., and Beauchemin, N. The expression of mouse biliary glycoprotein, a carcinoembryonic antigen-related gene, is down-regulated in malignant mouse tissues. Cancer Res., 53: 4938-4945, 1993.
27. Kleinerman, D. I., Troncoso, P., Lin, S-H., Pisters, L. L., Sherwood, E. R., Brooks, T., von Eschenbach, A. C., and Hsieh, J-T. Consistent expression of an epithelial cell adhesion molecule (C-CAM) during human prostate development and loss of expression in prostate cancer: implication as a tumor suppressor. Cancer Res., 55: 1215-1220, 1995.
28. Kleinerman, D. I., Dinney, C. P. N., Zhang, W. W., Lin, S-H., Van, N. T., and Hsieh, J. T. Suppression of human bladder cancer growth by increased expression of C-CAM1 gene in an orthotopic model. Cancer Res., 56: 3431-3435, 1996.
29. Ilantzis, C., Jothy, S., Alpert, L., Draber, P., and Stanners, C. P. Cell surface levels of human carcinoembryonic antigen are negatively correlated with colonocyte differentiation in colon carcinogenesis. Lab. Invest., in press, 1997.
30. Hixson, D. C., McEntire, K. D., and Öbrink, B. Alterations in the expression of a hepatocyte cell adhesion molecule by transplantable rat hepatocellular carcinomas. Cancer Res., 45: 3742-3749, 1985.
31. Hinoda, Y., Imai, K., Nakagawa, N., Ibayashi, Y., Nakano, T., Paxton, R. J., Shively, J. E., and Yachi, A. Transcription of biliary glycoprotein I gene in malignant and non-malignant human liver tissues. Int. J. Cancer, 45: 875-878, 1990.
32. Ohwada, A., Takahashi, H., Nagaoka, T., and Kira, S. Biliary glycoprotein mRNA expression is increased in primary lung cancer, especially in squamous coll carcinoma. Am. J. Resp. Cell Mol. Biol., 11: 214-220, 1994.
33. Kuprina, N. I., Baranov, V. N., Yazova, A. K., Rudinskaya, T. D., Escribano, M., Cordier, J., Gleiberman, A. S., and Goussev, A. I. The antigen of bile canaliculi of the mouse hepatocyte: identification and ultrastructural localization. Histochemistry, 94: 179-186, 1990.
34. Brattain, M. G., Stobel-Stevens, J., Fine, D., Webb, M., and Sarrif, A. M. Establishment of different mouse colonie carcinoma cell lines with different metastatic properties. Cancer Res., 40: 2142-2146, 1980.
35. McCuaig, K., Rosenberg, M., Nédellec, P., Turbide, C. and Beauchemin. N. Expression of the Bgp gene and characterization of mouse colon biliary glycoprotein isoforms. Gene (Amst.), 127: 173-183, 1993.
36. Morgenstern, J. P., and Land, H. Advanced mammalian gene transfer: high titer retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res., 18: 3587-3596, 1990.
37. Ishii, S., Steele, G., Ford, R., Paliotti, G., Thomas, P., Andrews, C., Hansen, H. J., Goldenberg, D. M., and Jessup, J. M. Normal colonic epithelium adheres to carcinoembryonic antigen and type IV collagen. Gastroenterology, 106: 1242-1250, 1994.
38. Odin, P., Tingström, A., and Öbrink, B. Chemical characterization of cell-CAM 105, a cell-adhesion molecule isolated from rat liver membranes. Biochem J., 236: 559-568, 1986.
39. Hunter, I., Sawa, H., Edlund, M., and Öbrink, B. Evidence for regulated dimerization of C-CAM in epithelial cells. Biochem. J., 320: 847-853, 1996.
40. Kleinerman, D. I., Zhang W-W., Lin, S-H., Van, N. T., von Eschenbach, A. C., and Hsieh, J-T. Application of a tumor suppressor (C-CAM1)-expressing recombinant adenovirus in androgen-independent human prostate cancer therapy: a preclinical study. Cancer Res., 55: 2831-2836, 1995.
41. Frängsmyr, I., Baranov, V., Prall, F., Yeung, M. M-W., Wagener, C., and Hammarström, S. Cell-and region-specific expression of biliary glycoprotein and its messenger RNA in normal human colonic mucosa. Cancer Res., 55: 2963-2967, 1995.
42. Lin, S-H., Luo, W., Earley, K., Cheung, P., and Hixson, D. C. Structure and function of C-CAM1: effects of the cytoplasmic domain on cell aggregation. Biochem. J., 311: 239-245, 1995.
43. Crumpton, M. N., and Dedman, J. R. Protein terminology tangle. Nature (Lond.), 345: 212, 1990.
44. Ocklind, C., Odin, P., and Öbrink, B. Two different cell adhesion molecules, cell-CAM 105 and a calcium-dependent protein, occur on the surface of hepatocytes. Exp. Cell Res., 151: 29-45, 1984.
45. Theobald, J., Smith, P. D., Jacob, S. M., and Moss, S. E. Expression of annexin VI in A431 carcinoma cells suppresses proliferation: a possible role for annexin VI in cell growth regulation. Biochim. Biophys. Acta, 1223: 383-390, 1994.
46. Theobald, J., Hanby, A., Patel, K., and Moss, S. E. Annexin VI has tumour-suppressor activity in A431 squamous epithelial carcinoma cells. Br. J. Cancer, 71: 786-788, 1995.
47. Edlund, M., Blikstad, I., and Öbrink, B. Calmodulin binds to specific sequences in the cytoplasmic domain of C-CAM and down-regulates C-CAM self-association. J. Biol. Chem., 271: 1393-1399, 1996.
48. Odin, P., and Öbrink, B. Dynamic expression of the cell adhesion molecule cell-CAM 105 in fetal and regenerating rat liver. Exp. Cell Res., 164: 103-114, 1986.
49. Thompson, N. L., Lin, S-H., Panzica, M. A., and Hixson, D. C. Cell CAM 105 isoform RNA expression is differentially regulated during rat liver regeneration and carcinogenesis. Pathobiology, 62: 209-220, 1994.
50. Hixson, D. C., and McEntire, K. D. Detection of an altered form of cell-CAM 105 on rat transplantable and primary hepatocellular carcinomas. Cancer Res., 49: 6788-6794, 1989.
51. Nollau, P., Pratt, F., Scheller, H., Wagener, C., and Neumaier, M. CD66a, CGM2 and NCA in colorectal cancer. Cancer Res., in press, 1997.